In various embodiments, a tissue thickness compensator can comprise one or more capsules and/or pockets comprising at least one medicament therein. In at least one embodiment, staples can be fired through the tissue thickness compensator to rupture the capsules. In certain embodiments, a firing member, or knife, can be advanced through the tissue thickness compensator to rupture the capsules.

A surgical system comprising an electric motor and a surgical instrument is disclosed. The surgical instrument comprises a housing, a shaft extending from the housing, a fastener cartridge, an anvil, a translatable drive member, and a rotatable actuator knob. The housing comprises an input shaft operably coupled to the electric motor. The input shaft is rotatable in a first mode by the electric motor. The fastener cartridge comprises a plurality of fasteners removably stored therein. The anvil is configured to deform the fasteners. The translatable drive member is configured to move the anvil toward and away from the fastener cartridge. The translatable drive member is movable by the electric motor in the first mode. The rotatable actuator knob is configured to be rotated multiple full rotations in a second mode to manually cause the input shaft to move the anvil.

A surgical stapling apparatus includes a loading unit having first and second jaw members, a drive beam, and a firing lockout assembly. The drive beam is axially movable within the loading unit during a firing sequence. The firing sequence includes an advancement stroke which moves the first and second jaw members to an approximated position and a retraction stroke which moves the first and second jaw members to an unapproximated position. The firing lockout assembly includes an iterating plate, a capture gear, and a lockout pin. The iterating plate is disposed adjacent to the drive beam and is incrementally movable proximally within the loading unit during the firing sequence. The capture gear is rotatable between first and second positions during the firing sequence and is configured to move the iterating plate. The lockout pin is configured to lock the drive beam after a pre-determined number of firing sequences.

A surgical tool for use with a robotic system that includes a tool drive assembly that is operatively coupled to a control unit of the robotic system that is operable by inputs from an operator and is configured to robotically-generate output motions. A drive system is configured to interface with a corresponding portion of the tool drive assembly for receiving the robotically-generated output motions and applying the output motions to a drive shaft assembly which is configured to apply control motions to a surgical end effector operably coupled thereto. A manually-actuatable control system operably interfaces with the drive shaft assembly to facilitate the selective application of manually-generated control motions to the drive shaft assembly.

A forceps includes an end effector assembly having first and second jaw members movable between a spaced-apart position and an approximated position for grasping tissue therebetween. A knife assembly having a cutting blade disposed at a distal end thereof is also provided. The knife assembly is translatable relative to the end effector assembly between a retracted position and an extended position, wherein the cutting blade extends between the jaw members to cut tissue grasped therebetween. The knife assembly includes a proximal component and a first distal component that includes the cutting blade. The proximal and first distal components are removably coupled to one another to facilitate replacement of the first distal component. Methods of preparing such forceps for reuse are also provided.

A surgical instrument is disclosed comprising an end effector including a first jaw and a second jaw, wherein the first jaw is rotatable relative to the second jaw, and a closure system configured to close the first jaw during a closure stroke. The surgical instrument further comprises an articulation joint rotatably connecting the end effector to the shaft, an articulation system configured to articulate the end effector relative to the shaft, and a firing system operably engaged with the electric motor, wherein the firing member is configured to move through the end effector during a firing stroke. The surgical instrument further comprises a first rotatable member configured to selectively synchronize the motion of the firing system with the motion of the articulation system and a second rotatable member operably engageable with the articulation system, wherein the closure system is configured to stop the rotation of the second rotatable member.

Surgical stapling instruments are disclosed comprising a staple cartridge, a firing member, and a cartridge lockout configured to prevent the firing member from being advanced through the staple cartridge if the staple cartridge has been already spent. The stapling instruments further comprise a lockout in the shaft that responds to the cartridge lockout blocking the firing member.

A powered handle assembly includes a motor assembly, a rack, a spur gear, and a manual retract mechanism. The spur gear is movable from a position engaged with the motor assembly and the rack to a positioned disengaged from the motor assembly and engaged with the rack to facilitate manual retraction of the rack.

A method is disclosed. The method can comprise obtaining a first staple cartridge and obtaining a second staple cartridge, wherein the first staple cartridge and the second staple cartridge comprise the same length and the same width. The method can further comprise inserting the first staple cartridge into a channel comprising a keyed profile, wherein complete insertion of the first staple cartridge into the channel is prevented by the keyed profile. Additionally, the method can comprise inserting the second staple cartridge into the channel, wherein complete insertion of the second staple cartridge into the channel is permitted by the keyed profile.

In various embodiments, a layer of material can comprise a body, a proximal end portion, and a distal end portion. The proximal end portion can be releasably secured to a staple cartridge of a surgical end effector, and the distal end portion can be releasably secured to an anvil of the surgical end effector. The layer of material can comprise a tissue thickness compensator.