A tissue cutting device has an outer sleeve with a distal window and an inner cutting sleeve which moves past the window to cut tissue. The inner cutting sleeve has a lumen which may have a larger proximal diameter than distal diameter. A perimeter of the window may comprise a dielectric material. A distal edge of the inner sleeve may be displaced inwardly.

A medical device includes an elongated sleeve having a longitudinal axis, a proximal end and a distal end. A ceramic cutting member includes both a cutting window having sharp edges and one or more flutes with cutting burrs circumferentially spaced-apart from the cutting window. An electrode may be placed between a pair of flutes and opposite to the cutting window. A motor drive is coupled to the proximal end of the elongated sleeve to rotate the ceramic cutting member cut bone with the flute(s) and soft tissue with the cutting window. The electrode provides cautery or radiofrequency ablation of tissue when the sleeve and ceramic cutting member are not being rotated.

A surgical instrument includes a hollow member having a sidewall provided with a window and a closure member movably connected to the hollow member for alternately covering and uncovering the window. The hollow member has a first clamping surface along an edge of the window, while the closure member has a second clamping surface opposing the first clamping surface and disposable substantially adjacent thereto in a clamping or closure configuration of the instrument. The instrument additionally comprises a tissue occlusion component mounted to at least one of the hollow member and the closure member for acting on tissues gripped between the first clamping surface and the second clamping surface, to couple the tissues to each other.

Prosthetic valve systems for treating a native valve exhibiting regurgitation can include a support structure in which a separate prosthetic heart valve can be placed. A method for implant a prosthetic valve system can include advancing a first catheter delivery sheath through an introducer sheath and into a left ventricle of a patient's heart, deploying at least a portion of a support structure from the first catheter delivery sheath and positioning the support structure around native leaflets of the patient's native mitral valve, positioning a prosthetic heart valve in a radially collapsed configuration within the patient's native mitral valve, and expanding the prosthetic heart valve from the radially collapsed configuration to a radially expanded configuration, wherein the prosthetic heart valve contacts the native leaflets from within the patient's native mitral valve and is separated from the support structure by the native leaflets.

A biopsy device for acquiring a tissue sample is disclosed. The biopsy device comprises a partoff mechanism which can have at least a tab and an actuator. The actuator can be used to control the angle of the tab and thus partoff a tissue sample. The tab may be on a cutter tube, which may have a sharp distal end which may core the samples from the mass of tissue. Multiple tissue samples may be collected.

A medical device includes an elongated sleeve having a longitudinal axis, a proximal end and a distal end. A ceramic cutting member includes both a cutting window having sharp edges and one or more flutes with cutting burrs circumferentially spaced-apart from the cutting window. An electrode may be placed between a pair of flutes and opposite to the cutting window. A motor drive is coupled to the proximal end of the elongated sleeve to rotate the ceramic cutting member cut bone with the flute(s) and soft tissue with the cutting window. The electrode provides cautery or radiofrequency ablation of tissue when the sleeve and ceramic cutting member are not being rotated.

A debrider that includes an outer tubular member, and an inner tubular member located inside the outer tubular member. The inner tubular member includes an aspiration channel. The outer tubular member includes a declogging feature. The declogging feature extends from an inside distal wall of the outer tubular member in a proximal direction towards a distal wall of the inner member. The declogging feature is at least partially received into the aspiration channel through a distal opening defined in the distal end of the inner member, and is configured to push any matter located inside the aspiration channel in a proximal direction.

A tissue resecting instrument includes an end effector assembly having a proximal hub housing, outer and inner shafts extending therefrom, and an inner core drive assembly to rotate and reciprocate the inner shaft relative to the outer shaft. The inner core drive assembly includes a proximal receiver that receives a rotational input and rotates in response and includes a seal member disposed thereon. The rotation of the proximal receiver effects rotation of a connector and reciprocation of the connector between a proximal position and a distal position. The connector is operably coupled to the inner shaft such that the rotation and reciprocation of the connector effects the rotation and reciprocation of the inner shaft. In the proximal position, the connector and the seal member establish a seal that blocks outflow. In the distal position, the connector is displaced from the seal member to permit outflow.

A tissue specimen retrieval device includes a first shaft and a second shaft telescopically movable relative to the first shaft. The second shaft supports an end effector assembly at a distal end portion thereof and is movable relative to the first shaft between a retracted position, wherein the end effector assembly is disposed within the first shaft, and a deployed position, wherein the end effector assembly extends distally from the first shaft. The end effector assembly includes a tissue specimen bag supported by a first arm and a second arm. The first and second arms are configured to open the tissue specimen bag when the second shaft is deployed. A cut-off slider is operably associated with the distal end portion of the second shaft and is configured to sever the tissue specimen bag upon retraction of the second shaft.

An extraction device can include a delivery shaft having a lumen and a distal end, a first wire forming a first arc and being positionable distal to the distal end of the delivery shaft while ends of the first arc are at a distalmost end of the delivery shaft, and a second wire forming a second arc and being positionable distal to the distal end of the delivery shaft while ends of the second arc are at the distalmost end of the delivery shaft. A distalmost extent of the first wire is distal to a distalmost extent of the second wire. The first wire and the second wire are separately retractable relative to the delivery shaft.