A Catheter for the transfer of human embryos including an outer catheter characterized by an integrated element of transverse folds in the shape of an “accordion” at a specific distance from its tip. When being compact, the element of transverse folds is 1 cm long while the distance of its center from the tip of the catheter is 5.5 cm but can vary +/−1 cm. The element of transverse folds has the ability to bend, expand, compress and generally be configured in the desired shape and angle by the operating clinician in order to facilitate its passage through the cervical channel. The shape and angle are capable of being re-configured by the operating clinician if deemed necessary. The element of transverse folds is also capable of automatically adjusting in shape and angle during its passage through the cervix, following the anatomy of the cervical channel.

A device for collecting uterine fluid is described which can be used in vivo in both animals and humans, without said use causing dilution of fluid components or damage to the endometrium.

A device for collecting uterine fluid is described which can be used in vivo in both animals and humans, without said use causing dilution of fluid components or damage to the endometrium.

Methods for non-invasive retrieval of viable (i.e., able to be fertilized) oocytes from the uterus via a combination of unique ovarian stimulation and uterine lavage technology. These methods may eliminate the need for an invasive surgical procedure. Embodiments include the use of a novel hormonal protocol, including the use of injectable gonadotropins, to induce the release of immature oocytes from the ovaries of a patient. The immature oocytes mature as they transit the fallopian tubes such that mature, viable oocytes may be collected from the uterus via a uterine lavage procedure. Further embodiments include the use of a novel hormonal protocol, including the administration of Prostaglandins, Estradiol, and/or Progesterone Blockers, to accelerate transport of oocytes through the fallopian tubes. Further embodiments include kits for uterine lavage, compositions suitable for triggering and inducing superovulation, and compositions suitable for accelerating tubal transport of mature oocytes in a female patient.

Methods for non-invasive retrieval of viable (i.e., able to be fertilized) oocytes from the uterus via a combination of unique ovarian stimulation and uterine lavage technology. These methods may eliminate the need for an invasive surgical procedure. Embodiments include the use of a novel hormonal protocol, including the use of injectable gonadotropins, to induce the release of immature oocytes from the ovaries of a patient. The immature oocytes mature as they transit the fallopian tubes such that mature, viable oocytes may be collected from the uterus via a uterine lavage procedure. Further embodiments include the use of a novel hormonal protocol, including the administration of Prostaglandins, Estradiol, and/or Progesterone Blockers, to accelerate transport of oocytes through the fallopian tubes. Further embodiments include kits for uterine lavage, compositions suitable for triggering and inducing superovulation, and compositions suitable for accelerating tubal transport of mature oocytes in a female patient.

A needle for extraction of biological material from a fluid filled intracorporeal sac, the needle comprising: a shaft comprising a first flow channel comprising an inlet for aspirating biological material from the intracorporeal sac and a second flow channel comprising an outlet for supplying a flushing fluid to the intracorporeal sac; and wherein the outlet is configured to direct the flushing fluid in a direction substantially transverse to the first flow channel; and methods using the needle.

A needle for extraction of biological material from a fluid filled intracorporeal sac, the needle comprising: a shaft comprising a first flow channel comprising an inlet for aspirating biological material from the intracorporeal sac and a second flow channel comprising an outlet for supplying a flushing fluid to the intracorporeal sac; and wherein the outlet is configured to direct the flushing fluid in a direction substantially transverse to the first flow channel; and methods using the needle.

Described herein are devices, systems, and methods to aid in the manipulation of cells. The devices, methods, and systems disclosed herein can be applied towards, for example, automation of the in vitro fertilization process.

Described herein are devices, systems, and methods to aid in the manipulation of cells. The devices, methods, and systems disclosed herein can be applied towards, for example, automation of the in vitro fertilization process.

The present invention relates to a catheter for treating ectopic pregnancy, of which one end is inserted into the fallopian tube through the vaginal cavity, and the other end is exposed to the outside of the body, wherein the catheter comprises: at least one passage portion forming a liquid passage entering through the one end or the other end; a penetrative portion connected to the one end, and including a foremost end for penetrating the gestational sac; and a connecting portion connected to the other end, and capable of being coupled to at least one syringe tool for injecting or suctioning the liquid. Accordingly, side effects from open surgery can be prevented, and excellent treatment effects can be obtained by more safely and quickly treating ectopic pregnancy.