A system and a method are disclosed for forming an anastomosis between a first layer of tissue and a second layer of tissue of a patient's body. The system includes a first anastomosis device component and a second anastomosis device component configured to interact with the first anastomosis device component. The first anastomosis device component is configured to be delivered to a first lumen inside the patient's body. The second anastomosis device component is configured to be delivered to a second lumen inside the patient's body. The second anastomosis device includes one or more sensors configured to capture sensor data for determining an alignment of the second anastomosis device component relative to the first anastomosis device component, or for characterizing the position or orientation of the second anastomosis device component in three-dimensional space.

A system to treat a patient comprises a user interface that allows a physician to view an image of tissue to be treated in order to develop a treatment plan to resect tissue with a predefined removal profile. The image may comprise a plurality of images, and the planned treatment is shown on the images. The treatment probe may comprise an anchor, and the image shown on the screen may have a reference image marker shown on the screen corresponding to the anchor. The planned tissue removal profile can be displayed and scaled to the image of the target tissue of an organ such as the prostate, and the physician can adjust the treatment profile based on the scaled images to provide a treatment profile in three dimensions. The images shown on the display may comprise segmented images of the patient with treatment plan overlaid on the images.

In general, devices, systems, and methods for fiducial identification and tracking are provided.

A catheter system for cryoablation of the stomach, comprising: a catheter and at least one inflatable cryoballoon which is fastened to the catheter and exhibits a contact curve along which the cryoballoon can be brought into contact with the fundus, wherein the contact curve is a closed curve on the surface of the cryoballoon, and the cryoballoon contains a first cooling arrangement which extends along less than three quarters of the length of the contact curve.

Described here are devices, systems, and methods for applying pulsed or modulated electric fields to tissue. In some variations, a method of treating may comprise advancing a pulsed electric field device into a body cavity of a patient. The pulsed electric field device may comprise an elongate body and an expandable member coupled to the elongate body. The expandable member may comprise an electrode array. A pulsed waveform may be delivered to the electrode array to generate a pulsed or modulated electric field thereby treating tissue.

A computer-assisted medical device is configured and used to endoluminally navigate to a location in the gastrointestinal system and there treat certain body lumen wall areas while avoiding other body lumen wall areas. Embodiments ablate the inner mucosal layer and sub-mucosal nerve plexus of the stomach, duodenum and jejunum to effect treatment of insulin resistance and metabolic disorders, such as Type II diabetes (T2D), polycystic ovarian syndrome (PCOS), non-alcoholic steatohepatitis (NASH), non-alcoholic fatty liver disease (NAFLD), congestive heart failure (CHF) and obstructive sleep apnea (OSA). Various sensors are used to assist a clinical operator to navigate from the mouth through the pyloric sphincter and into and through the duodenum and/or jejunum. Various sensors are used to map and identify portions of the duodenum and/or jejunum. Various lumen wall ablation devices and methods are described. Various post-treatment assessments are described.

A smooth muscle stimulation device is intended for use with any one of a variety of electrosurgical units (ESU's) of the type used in tissue resection and other procedures that risk damage to non-target tissues. The smooth muscle stimulation devices typically include an enclosure with stimulation circuitry configured to generate a stimulatory electrical signal which when delivered to a target anatomy induces an observable response in the target anatomy during a medical procedure. An input connector on the enclosure detachably couples to a power output of the ESU, and an output connector on the enclosure detachably couples to an electrosurgical tool. Switching circuitry within the enclosure selectively connects either the power output of the ESU or the stimulatory electrical signal of the stimulation circuitry to the output connector in response to user input.

In general, devices, systems, and methods for control of one visualization with another are provided.

A dual amplifier apparatus is disclosed. The apparatus includes an energy module having a controller and a first and second power amplifier circuit coupled to the controller. The first and second power amplifier circuits are configured to receive and amplify an input signal to generate a first output signal into a load coupled to the output of the first and second power amplifier circuit. A power rating of the first amplifier circuit is different from a power rating of the second amplifier circuit. The controller is configured to select the first or the second power amplifier circuit.

Systems and methods for the treatment or prevention of dysbiosis in the gastrointestinal tract of an individual and includes implantable devices adapted to release therapeutic or restorative microbiota to an individual's GI tract as well as ablation systems that can ablate residing microbiota before administering the restorative microbiota.