A laminated laser window having an inner layer transparent to light having wavelengths between 3.5 micrometers and 12 micrometers and having as an outer surface a nanometric-thick outer layer of SiO2. The window allows the passage of light within this wavelength range, for example from a CO2 laser. In The SiO2 outer layer maintains biocompatibility when used in laser devices for insertion into externally accessible bodily cavities.

In one aspect, methods of treating human papillomavirus (HPV)-associated growths are provided in which nano-pulse stimulation is applied at the site of a cancer. In another aspect, devices and computer systems for delivering nano-pulse stimulation for the treatment of HPV-associated growths are provided.

The present invention discloses medical systems and methods adapted for the delivery of various medical components such as microwave antennas within or on a body for performing one or more medical procedures. Several embodiments herein disclose medical systems comprising a combination of one or more medical components and one or more elongate steerable or non-steerable arms that are adapted to mechanically manipulate the one or more medical components. Several embodiments of microwave antennas are disclosed that comprise an additional diagnostic or therapeutic modality located on or in the vicinity of the microwave antennas.

A system includes a device associated with an endoscopy guided procedure including a housing defining a housing channel with at least a portion of the housing configured for deployment within a cavity. The device further includes a plurality of bodies defining respective channels defined within the housing. The housing defines a longitudinal axis, and the plurality of channels extends throughout the housing around the longitudinal axis. Each of the plurality of channels accommodates selective activation of radiation emittance from a predetermined different position along the housing via one or more radiation elements such that the plurality of channels collectively provides a predetermined spatial distribution of a radiation treatment to a target area along the cavity.

A system for controlling operation of a radiofrequency treatment device to apply radiofrequency energy to tissue to treat tissue to create lesions without ablating the tissue. The system includes a first treatment device having a plurality of electrodes. The electrodes are maintained in axial alignment and fixed radial spacing in retracted and extended positions. The device includes a basket having a plurality of arms. The arms are maintained in a fixed radial spacing in the collapsed position of the basket.

A device and method for treating female urinary incontinence and also for treating fecal incontinence are presented. A fractional RF grid array is used to heat target tissue to a temperature of about 40-45? C. for a specified period of time, thus stimulating fibroblasts to produce type 1 collagen preferably without producing significant amounts of type 3 collagen. The device includes a temperature sensor and a control circuit to maintain the desired temperature of the target tissue and avoid overheating. Target tissue includes tissue in and around the urethra, and in and around the anus including the perineum. The wand to which the RF grid array is mounted has visible gradations on it so that the user can treat one area at a time, then reliably move the grid array to the next adjacent area even though the grid array is hidden from view inside a portion of the body. The device can also be used for vaginoplasty.

A system for controlling operation of a radiofrequency treatment device to apply radiofrequency energy to tissue to treat tissue to create lesions without ablating the tissue. The system includes a device having flexible outer tube, an expandable basket having a plurality of arms movable from a collapsed position to an expanded position, a plurality of electrodes movable from a retracted position to an extended position to extend through the openings in the arms, and an advancer slidably disposed within the outer tube to move the electrodes. An elongated spacer is positioned within the outer tube, the spacer having a central lumen to receive the advancer and to maintain a central position of the advancer.

Ablation catheters and systems include multiple inline chambers for containing and heating an ablative agent. The heating chamber includes one or more channels to increase the contact surface area of the ablative agent with the walls of the heating chamber to provide more efficient heating. Induction heating is used to heat a chamber and vaporize a fluid within by wrapping a coil about a ferromagnetic chamber and providing an alternating current to the coil. A magnetic field is created in the area surrounding the chamber which induces electric current flow in the chamber, heating the chamber and vaporizing the fluid inside. Positioning elements help maintain the device in the proper position with respect to the target tissue and also prevent the passage of ablative agent to normal tissues.

An ablation device may generally comprise a first electrode, a plurality of second electrodes, and a grounding pad. Each of the plurality of second electrodes may comprise a first conductive section, a second conductive section, and a non-conductive section between the first conductive section and the second conductive section. The first electrode and each of the plurality of second electrodes may be coupled to an energy source delivering a series of electrical pulses to tissue to induce cell necrosis by irreversible electroporation.

An add-on cap for electroporation of tissue including: at least one closed sidewall, such as a cylindrical sidewall; a proximal open end; a distal open end; the at least one closed sidewall and the proximal and distal open ends defining a hollow body having an internal volume; two electrodes on opposite sides of the internal volume, the electrodes configured to apply an electric field for electroporation of tissue inside the internal volume, wherein the proximal open end is sealingly engaged to a tip of an instrument, such as an endoscope. A system for electroporation of tissue including the add-on cap and an endoscope.