Wearable heat transfer devices and associated systems and methods are disclosed herein. In some embodiments, a representative heat transfer device can comprise (i) a thermoelectric component (TEC) including a first side configured to be operated at a desired temperature and a second side opposite the first side, (ii) a thermally conductive contact member thermally coupled to the TEC, and (iii) a heat transfer system configured to distribute heat from the TEC. The heat transfer system includes a heat transfer structure thermally coupled to the TEC, and a heat exchanger thermally coupled to the heat transfer structure.

A fat-reducing treatment device and a freezing fat-reducing instrument are disclosed. The fat-reducing treatment device includes at least two concave cups (100), each concave cup (100) having a trough-shaped body (110) and a connecting end (120). The at least two concave cups (100) are coupled together at the connecting ends (120) such as to rotatable about a first axis (A). The trough-shaped bodies (110) of the at least two concave cups (100) are brought into communication with each other at the connecting ends (120). The first axis (A) is oriented in a first direction, and the trough-shaped bodies (110) extend in a second direction (B) and are open in a third direction. With this arrangement, the trough-shaped bodies (110) can accommodate the placement of a larger abdomen or waist portion of a human body. In this way, the trough-shaped bodies (110) can adapt to waist and abdomen portions with different contours and curvatures and provide a large fat reduction treatment area, resulting in a simpler treatment procedure, a shorter treatment time, higher fat reduction efficiency, improved fat reduction outcomes and enhanced user experiences and satisfaction.

An ablation probe having a separable outer sleeve and a freezing function, comprising: an inner probe (101, 201, 301, 401), an outer sleeve (102, 202, 302, 402), and a handle (105, 205, 305, 405). The inner probe (101, 201, 301, 401) is slidably connected to the outer sleeve (102, 202, 302, 402); one end of the inner probe (101, 201, 301, 401) is fixed to one end of the handle (105, 205, 305, 405); said ablation probe further comprises a separating assembly; the separating assembly comprises a first separable member (103) and a second separable member (104); the first separable member (103) and the second separable member (104) are detachably connected; the first separable member (103) is fixed to the outer sleeve (102, 202, 302, 402); the second separable member (104) is fixed to the handle (105, 205, 305, 405); the outer sleeve (102, 202, 302, 402) is a heat-insulating tube. The slide of the outer sleeve (102, 202, 302, 402) on the surface of the inner probe (101, 201, 301, 401) can change the size and distribution of the ablation area of the inner probe (101, 201, 301, 401); the separable structure can form a channel between the outside of the body and the target area of treatment by means of the outer sleeve (102, 202, 302, 402) for biopsy, drug delivery, and hemostasis; the separable structure can be designed into a non-reusable structure for one-time use only to improve the safe usage of the ablation probe.

Present disclosure provides a cooling device with safety features and methods for controlling temperature of the cooling device for safe cooling of target surface.

A method for treating skin, including: delivering one or more pulses of non-converging ultrasonic energy through a surface area size in a range of 3 mm.sup.2-7 mm.sup.2, wherein each pulse having an intensity in a range of 5 W/cm.sup.2-60 W/cm.sup.2 and a time duration in which the ultrasonic energy is actively transmitted in a range of 1-10 seconds per pulse, wherein the non-converging ultrasonic energy is delivered from a fixed position to one or more skin regions having a maximal surface area size in a range of 5 cm.sup.2-100 cm.sup.2.

Systems and techniques for a medical apparatus, specifically a handheld electrosurgical device, are described herein. In an example, the device includes an electrosurgical end effector, a temperature sensor to measure a temperature of the end effector, a cooler to cool the end effector based on the measured temperature, and a heater to heat the end effector based on the measured temperature. The end effector may be kept within a temperature range or band such as by allowing the end effector to be heated or cooled as desired during a surgical procedure.

Cryocatheter including an elongated flexible catheter member having a short rigid catheter tip for introduction into a therapy site and a heat exchange arrangement for freezing the catheter tip to a cryo-temperature from between about −15° C. to about −30° C. for freezing human tissue at the therapy site. Cerebral medical procedures include inter alia employing a local ice ball for sealing a bleeding rupture in an arterial wall in the case of a stroke hemorrhage, employing a local ice ball for mapping electrical disorder foci in a brain, for example, epileptic foci, and the like.

A method in accordance with a particular embodiment of the present invention includes increasing a concentration of a modified or unmodified saccharide within a subject's skin, applying an applicator to the subject's skin, and cooling the subject's skin via a heat-transfer surface of the applicator. The saccharide within the subject's skin can enhance a resistance of at least some cells within the subject's skin to damage associated with the cooling. A corresponding system includes the applicator, the saccharide, and an energy-delivery device. The energy-delivery device can be configured to apply ultrasound, optical, thermal, or another type of energy to the subject's skin to drive the saccharide into the subject's skin. The system can also include a penetration enhancer configured to enhance penetration of the saccharide into the subject's skin. The penetration enhancer can be applied with the saccharide or separately.

An electrosurgical apparatus and method for performing thermal treatment in the gastrointestinal tract, e.g. to ablate duodenal mucosal tissue. The apparatus comprises an instrument having a flexible cable and an applicator suitable for use with a gastroscope, which can be deployed within a patient to delivery energy in a targeted or otherwise controllable manner. The applicator can deliver microwave energy by radiation. The direct and depth-limited nature of microwave energy can be make it more effective than treatments that rely on thermal conduction. The applicator may include a radially extendable portion arranged to move an microwave energy delivery structure into contact with duodenal mucosal tissue at the treatment region. The applicator may comprise any of a balloon, bipolar radiator, movable paddle, and rotatable roller element.

An electrosurgical apparatus and method for performing thermal treatment in the gastrointestinal tract, e.g. to ablate duodenal mucosal tissue. The apparatus comprises an instrument having a flexible cable and an applicator suitable for use with a gastroscope, which can be deployed within a patient to delivery energy in a targeted or otherwise controllable manner. The applicator can deliver microwave energy by radiation. The direct and depth-limited nature of microwave energy can be make it more effective than treatments that rely on thermal conduction. The applicator may include a radially extendable portion arranged to move an microwave energy delivery structure into contact with duodenal mucosal tissue at the treatment region. The applicator may comprise any of a balloon, bipolar radiator, movable paddle, and rotatable roller element.