A system for inflating a cryogenic ablation catheter balloon, the system comprising a fluid source containing a fluid in a liquid state, a first supply line fluidly coupled to the fluid source and configured to be fluidly coupled to an internal space within the cryogenic ablation catheter balloon, the first supply line including an inline multi-stage pressure regulating system. The multi-stage pressure regulating system includes a first stage configured to cause the fluid to transition from the liquid state to a gas state, and a second stage downstream of the first stage configured to maintain the fluid downstream of the second stage at a pressure corresponding to an inflation pressure of cryogenic ablation catheter balloon.

Provided are a method for adjusting an in-tank pressure of a working medium storage tank and an apparatus for the same. The method includes: acquiring a backflow temperature collected by each of first thermocouples; counting the number of target backflow paths whose backflow temperature reaches a preset temperature; and adjusting an in-tank pressure of the working medium storage tank to a target in-tank pressure corresponding to the number of the target backflow paths according to the number of the target backflow paths and a corresponding relationship between a preset number of backflow paths and the in-tank pressure. The control box determines the target in-tank pressure corresponding to the number of the target backflow paths to realize automatic adjustment of the in-tank pressure of the working medium storage tank.

Disclosed is an electrical control system for minimally invasive tumor therapies. The electrical control system for minimally invasive tumor therapies includes a control module, a perfusion module and a power box. The perfusion module includes a working medium storage tank, a tank liquid level meter, a tank pressure sensor, a tank deflation valve, a liquid charging valve and an external working medium container. The power box is configured to supply power to the control module and the perfusion module. The control module is configured to receive working medium parameters sent by the tank liquid level meter and the tank pressure sensor, and to control, when the work medium parameters meet a perfusion condition, the tank deflation valve and the liquid charging valve to open or close respectively so as to input working medium from the external working medium container into the working medium storage tank.

Devices and systems for the selective positioning of an intravascular neuromodulation device are disclosed herein. Such systems can include, for example, an elongated shaft and a therapeutic assembly carried by a distal portion of the elongated shaft. The therapeutic assembly is configured for delivery within a blood vessel. The therapeutic assembly can include a pre-formed shape and can be transformable between a substantially straight delivery configuration; and a treatment configuration having the pre-formed helical shape to position the therapeutic assembly in stable contact with a wall of the body vessel. The therapeutic assembly can also include a mechanical decoupler operably connected to the therapeutic assembly that is configured to absorb at least a portion of a force exerted on the therapeutic assembly by the shaft so that the therapeutic assembly maintains a generally stationary position relative to the target site.

Disclosed herein are devices, systems, and method for multi-stage, reusable coupling. Such a coupler can have a formable flow path and can include a first sealing engagement and a second sealing engagement. The first sealing engagement can be configured to provide a first seal of the coupler at a first temperature condition. The second sealing engagement can be configured to provide a second seal of the coupler at a second temperature condition that is different from the first temperature condition.

A tethered system for cryogenic treatment is disclosed in which a hand piece having an elongate probe with a distal tip and a flexible length, at least one infusion lumen positioned through or along the elongate probe, and a liner may be tethered to a base station having a reservoir of a cryoablative fluid via a connection having an elongate flexible body. The connection defines at least one fluid lumen for delivery of the cryoablative fluid from the reservoir and to the infusion lumen within the hand piece.

Methods and devices for treating nasal airways are provided. Such devices and methods may improve airflow through an internal and/or external nasal valve, and comprise the use of mechanical re-shaping, energy application and other treatments to modify the shape, structure, and/or air flow characteristics of an internal nasal valve, an external nasal valve or other nasal airways.

The present invention provides a double-layer cryogenic inflatable balloon including an inflatable balloon assembly and a cryogenic balloon assembly. The inflatable balloon assembly includes an inflatable balloon, an outer catheter and a liquid-filling cavity provided with a liquid-filling chamber, the inflatable balloon, the outer catheter and the liquid-filling cavity being communicated with each other. The cryogenic balloon assembly includes a cryogenic balloon, an inner catheter and a fluid-diverting cavity provided with a gas return chamber as well as a gas inlet pipe and an inflation assembly, the cryogenic balloon, the inner catheter and the fluid-diverting cavity being communicated with each other, wherein the cryogenic balloon is located in the inflatable balloon, and the inner catheter is located in the outer catheter. The fluid-diverting cavity is further provided with a gas return channel, a liquid-filling channel, and a cork chamber, wherein the gas return channel has one end communicated with the gas return chamber and the other end communicated with the cork chamber. The liquid-filling channel has one end communicated with the cork chamber and the other end communicated with the liquid-filling chamber. The cork chamber is communicated with a gas return joint, and is internally provided with an adjustment structure. The fluid-diverting cavity is provided with a gas inlet chamber, and the gas inlet pipe penetrates through the cryogenic balloon, the inner catheter and the fluid-diverting cavity, the gas inlet pipe having one end located in the cryogenic balloon and the other end communicated with the gas inlet chamber. The gas inlet chamber is communicated with the inflation assembly, and the inflation assembly is used to input a refrigerant gas into the cryogenic balloon through a pipe.

A magnetic resonance imaging (MRI) guided surgical system is provided that includes one or more surgical tools having components configured to develop reactive effects when exposed to MR signals generated by the MRI system. The system includes a control system that can determine whether the MR system is generating MR signals, and if the control system determines that the MR system is generating MR signals, mitigates the reactive effects of MR signals on components of the surgical tools. The system can include a cryoablation system with a cryoprobe having a probe shaft being made of a metallic material. If the control system determines that the MR system is generating MR signals, the control system can electrically disconnect the cryoprobe and/or ignore electrical signals generated by the electric heater in response to exposure to MR signals, and/or initiate a cooling operation of the probe shaft, whereby the cooling operation.

An apparatus for performing cryosurgery, especially suited for the sacroiliac joint. The apparatus includes a first expansion tube having a first length; a second expansion tube having a second length, wherein the second length is longer than the first length; a first supply tube supplying a cooling agent to the first expansion tube; a second supply tube supplying another cooling agent to the second expansion tube; and a drain tube for removing cooling agents from an enclosed working part, wherein the first expansion tube supplies the cooling agent to a first portion of the working part, the second expansion tube supplies the another cooling agent to a second portion of the working part, the working part further including a tip; wherein the first expansion tube and the second expansion tube are positioned inside a casing.