The invention generally relates to systems and methods for therapeutically modulating nerves in or associated with a nasal region of a patient for the treatment of a rhinosinusitis condition.

An esophageal ablation system including a positioner, an elongated, flexible shaft extending from the positioner, and a microwave emitter assembly disposed near the distal end of the shaft. The emitter assembly includes one or more microwave antennas and a balloon for spacing the antennas relative to target tissue. The device may have an inner balloon for deploying the antenna. The systems, devices and methods disclosed are useful for treating Barrett's Esophagus, Esophageal Adenocarcinoma, and Squamous Cell Carcinoma.

An isolating circuit for electrosurgical generator arranged to produce radiofrequency (RF) energy and microwave energy for treating biological tissue. The generator has an RF channel and a microwave channel which are combined at signal combiner to enable the RF energy and microwave energy to be delivered into tissue along a common feed path. The isolating circuit comprises a tunable waveguide isolator at a junction between the microwave channel and signal combiner, and can include a capacitive structure between a ground conductor of the signal combiner and a conductive input section of the waveguide isolator to inhibit coupling of the RF energy and leakage of the microwave energy. The isolating circuit can combine into a single tunable unit all the necessary components to isolate the microwave and RF channels from one another whilst providing a high withstanding voltage.

An electrosurgical generator capable of supplying energy in a waveform that causes electroporation in biological tissue. The electrosurgical generator may comprise an electroporation waveform supply unit that is integrated with an electromagnetic signal supply unit for generating microwave electromagnetic signals and radiofrequency electromagnetic signals for treatment. The electrosurgical generator may be configured to deliver different types of energy along a common feed cable. The electroporation waveform supply unit comprises a DC power supply and a DC pulse generator. The DC power supply may include a DC-DC converter for up-converting a voltage output by an adjustable voltage supply. Each DC pulse may have a duration in the range 1 ns to 10 ms and a maximum amplitude in the range 10 V to 10 kV.

The invention relates to a modular electrosurgical system for using electromagnetic (EM) radiation, such as radio frequency (RF) or microwave EM radiation, to treat biological tissue. In one example, control of the modules is centralised in a remote computing device which can communicate wirelessly with the modules of the system. In one example, different optional modules may be combined together with core modules to provide the system with different electrosurgical capabilities.

A microstrip impedance transformer that permits efficient (i.e. low loss) coupling of a microwave feed line (e.g. a conventional 50Ω coaxial cable) to an instrument cable, where the instrument cable has a lower impedance (e.g. in the range 12 to 14Ω) and includes an internal passageway. The microstrip impedance transformer is configured to perform impedance matching between the microwave feed line and the instrument cable in a manner that does not adversely affect a separate feed, e.g. for delivering fluid, into the internal passageway.

A microwave ablation system includes: a microwave generator (110) configured to generate a microwave power signal; a microwave antenna (120) coupled to the microwave field to heat at least a portion of the target tissue; a light source (312) for supplying an optical signal to multiple fiber sensors (320) disposed on the microwave antenna (120); a photodetector (316) for detecting an optical signal reflected from the fiber sensors (320) and producing an electrical detection signal; a demodulation device for demodulating the electrical detection signal; and a processor for processing the demodulated signal to obtain temperature measurements at different locations in the ablation zone, which may be displayed to a user to facilitate the performance of an ablation procedure. The multiple fiber sensors (320) may include multiple fiber Bragg gratings etched in an optical fiber (315), which are immune to electromagnetic interference.

A microwave generator includes a microwave signal generator configured to deliver a microwave signal to a microwave instrument coupled to the microwave generator and a generator controller storing a plurality of resistance value indicators. A device ID reader is configured to measure a resistance of the coupled microwave instrument. The generator controller is configured to compare the measured resistance of the coupled microwave instrument with the plurality of resistance value indicators to identify a type of the coupled microwave instrument. An instrument monitoring controller is configured to communicate a data request to the coupled microwave instrument based on the identified type of the coupled microwave instrument. The generator controller is configured to set at least one operating threshold of the microwave generator based on one of an operating configuration corresponding to one of the plurality of resistance value indicators or data communicated from the coupled microwave instrument.

The electrosurgical systems and corresponding methods of the present disclosure involve an electrosurgical generator, sensing circuitry, and a controller. The electrosurgical generator includes a radio frequency (RF) output stage that supplies power to tissue. The sensing circuitry measures impedance of tissue. The controller controls the power supplied from the RF output stage to track a nonlinear power curve until the power supplied from the RF output stage has reached a predetermined peak power of the nonlinear power curve. The controller further determines whether a tissue reaction has occurred based on impedance measured by the sensing circuitry and controls the power supplied from the RF output stage during a cooling phase if the controller determines that a tissue reaction has occurred. The controller may further control the power supplied from the RF output stage to track a linear power curve.

The present disclosure relates to systems, devices and methods for providing visual guidance for navigating inside a patient's chest. An exemplary method includes presenting a three-dimensional (3D) model of a luminal network, generating, by an electromagnetic (EM) field generator, an EM field about the patient's chest, detecting a location of an EM sensor within the EM field, determining a position of a tool within the patient's chest based on the detected location of the EM sensor, displaying an indication of the position of the tool on the 3D model, receiving cone beam computed tomography (CBCT) image data of the patient's chest, detecting the location of the tool within the patient's chest based on the CBCT image data, and updating the indication of the position of the tool on the 3D model based on the detected location.