An electrosurgical apparatus and method for performing thermal treatment in the gastrointestinal tract, e.g. to ablate duodenal mucosal tissue. The apparatus comprises an instrument having a flexible cable and an applicator suitable for use with a gastroscope, which can be deployed within a patient to delivery energy in a targeted or otherwise controllable manner. The applicator can deliver microwave energy by radiation. The direct and depth-limited nature of microwave energy can be make it more effective than treatments that rely on thermal conduction. The applicator may include a radially extendable portion arranged to move an microwave energy delivery structure into contact with duodenal mucosal tissue at the treatment region. The applicator may comprise any of a balloon, bipolar radiator, movable paddle, and rotatable roller element.

An electrosurgical apparatus and method for performing thermal treatment in the gastrointestinal tract, e.g. to ablate duodenal mucosal tissue. The apparatus comprises an instrument having a flexible cable and an applicator suitable for use with a gastroscope, which can be deployed within a patient to delivery energy in a targeted or otherwise controllable manner. The applicator can deliver microwave energy by radiation. The direct and depth-limited nature of microwave energy can be make it more effective than treatments that rely on thermal conduction. The applicator may include a radially extendable portion arranged to move an microwave energy delivery structure into contact with duodenal mucosal tissue at the treatment region. The applicator may comprise any of a balloon, bipolar radiator, movable paddle, and rotatable roller element.

A locator assembly (100) for determining a location of an arrhythmogenic foci (632) in or near a heart (101). The locator assembly (100) includes a device body (112) and a plurality of electrodes (102). The plurality of electrodes (102) receive electrical signals from the heart (101) to determine the location of the arrhythmogenic foci (632). The plurality of electrodes (102) can be coupled to the device body (112). At least two of the plurality of electrodes (102) can positioned circumferentially about the device body (112). The plurality of electrodes (102) can be positionable so that the plurality of electrodes (102) are in electrical communication with the heart (101).

A method for determining a location of an arrhythmogenic foci (632) in or near a heart (101) includes the steps of positioning a locator assembly (100) within the heart (101), the locator assembly (100) including a plurality of electrodes (102) that receive electrical signals from the heart (101), generating a first signal array (733) from the electrical signals received by the plurality of electrodes (102) to determine an actual location of the arrhythmogenic foci (632), artificially stimulating the heart (101) based on the actual location determined by the first signal array (733) to generate a second signal array (733), and confirming the actual location of the arrhythmogenic foci (632) by comparing the first signal array (733) with the second signal array (735). In some embodiments, the locator assembly (100) includes a plurality of bipolar electrodes (102).

A system for neuromodulation includes a split-ring resonator (SRR) comprising a resonance circuit, the SRR being implantable in a cranial target site and a source of microwave signals, wherein the microwave signals are deliverable wirelessly to couple with the SRR to produce a localized electrical field, wherein the localized electrical field inhibits one or more neurons at the cranial target site with submillimeter spatial precision.

A variable-length microwave ablation probe is provided. The probe is configured to have a range of resonant frequencies. The probe includes a microwave antenna, an outer conductor, and a cap. The probe further includes a radiation window that is at least partially transparent to microwave energy. The distal boundary of the outer conductor or the proximal boundary of the cap varies in distance from the probe distal end. The probe can have a choke length, an arm length, a radiating portion length, and a cap length. The lengths can each affect the resonant frequency of the antenna. Some examples provide a variable choke length, a variable arm length, a variable radiating portion length, and/or a variable cap length.

The present invention relates to systems and devices for delivering energy to tissue for a wide variety of applications, including medical procedures (e.g., tissue ablation, resection, cautery, vascular thrombosis, treatment of cardiac arrhythmias and dysrhythmias, electrosurgery, tissue harvest, etc.). In particular, the present invention relates to systems and devices for the delivery of energy with a linear array of antenna components having optimized energy delivery characteristics. In certain embodiments, methods are provided for treating a tissue region (e.g., a tumor) through application of energy with the systems and devices of the present invention.

An electrosurgical vessel sealing device that can seal biological vessels using a confined microwave field that yields a well-defined seal location with low thermal margin. The device comprises a pair of jaws that are movable relative to each other to grip biological tissue. A blade for cutting the gripped tissue is slidable between the jaws. A coplanar microstrip antenna is mounted on the inner surface of one or both of the pair of jaws to emit microwave energy into the gap therebetween. The device may comprise a separate dissector element to enable fine tissue cutting and dissection to be performed.

A variable-length microwave ablation probe is provided. The probe is configured to have a range of resonant frequencies. The probe includes a microwave antenna, an outer conductor, and a cap. The probe further includes a radiation window that is at least partially transparent to microwave energy. The distal boundary of the outer conductor or the proximal boundary of the cap varies in distance from the probe distal end. The probe can have a choke length, an arm length, a radiating portion length, and a cap length. The lengths can each affect the resonant frequency of the antenna. Some examples provide a variable choke length, a variable arm length, a variable radiating portion length, and/or a variable cap length.

Examples of a probe for microwave ablation are disclosed. The probe comprises a feed coaxial cable and an antenna that has a cylindrical outer housing with a predetermined diameter and a predetermined length defining a cavity therein and a radiating conductor positioned within the cavity with a matching stepped portion. The antenna further comprises a dielectric material placed in the cavity between the radiating conductor and the outer housing of the antenna to increase the mechanical strength of the probe as well as to improve the power coupling to the tissue to be ablated. The design of the coaxial cavity of the antenna with radiating conductor with a stepped portion fitted into dielectric materials increases antenna's mechanical strength to withstand higher temperatures and reduces an energy reflected back to the feed coaxial cable due to a good impedance match between the antenna and the feed cable such that antennas with smaller length can be used to fit curved paths.