A knife assembly for use with a surgical instrument includes a knife having proximal and distal ends, the proximal end including an aperture defined therein having a series of spaced apart fins extending thereacross. A knife drive rod is included and is configured to operably engage the fins to secure the knife drive rod to the knife. A retention mechanism is operably disposed at a distal end of the knife drive rod and is configured to secure the knife drive rod in engagement between the fins.

A method for treatment of a tumor includes obtaining 3D imaging of the tumor; processing the 3D imaging of the tumor to obtain tumor morphology; determining a number of treatment sites, the locations of such sites, and the treatment dosage using a model of intratumoral treatment dynamics between vascular, intracellular, and extracellular space in order for the tumor to receive a therapeutic dosage at every location of the tumor; and treating the tumor at each of the determined treatment sites and with the determined treatment dosage. In some embodiments, the method further includes generating the model to include a plurality of interconnected volumes wherein each volume has one or more adjacent volumes with a shared boundary. One or more simulations of treatment over time may be conducted using the model, each simulation having a set of one or more initial parameters.

An ablation probe tip 100 having a shaft 102 with an insertion end 104 and an annular aperture 120 near the insertion end 104. A center of ablation 124 is located within the shaft 102 and surrounded by the annular aperture shaft 102. The ablation probe tip 100 may be part of an ablation probe system 50 that includes an ablation source 60 that provides ablation means 62 to the ablation probe tip 100. The center of ablation 124 is a focal region from which the ablation means 62 radiates through the annular aperture 120 to form an ablation zone 150, 160, 170. The system 50 has at least one intra-operative control selected from the group of: ablation zone positioning control, ablation zone shaping control, ablation center control, ablation zone temperature control, guided ablation volume/diameter control, and power loading control.

A flexible microwave ablation antenna and a microwave ablation needle including the same are disclosed. The flexible microwave ablation antenna including: a radiator for transmitting microwave for ablation; a coaxial cable for propagating the microwave for ablation generated by a microwave generator to the radiator; wherein the flexible microwave ablation antenna is bendable. Preferably, an annular composite structure is disposed around a periphery of the coaxial cable to suppress the electromagnetic wave from propagating along the coaxial cable in a reverse direction. The annular composite structure includes an annular non-metallic layer and an annular metallic layer surrounding the annular non-metallic layer. The annular metallic layer is electrically insulated from the coaxial cable.

A surgical probe includes a connection hub, an antenna assembly, and an outer jacket. The antenna assembly is coupled to the connection hub, extends distally from the connection hub, and includes a radiating portion coupled thereto at the distal end thereof. The radiating portion is configured to deliver energy to tissue to treat tissue. The outer jacket is coupled to the connection hub, extends distally therefrom, and is disposed about the radiating portion. The outer jacket includes a distal end member configured to be spaced-apart from the radiating portion a target axial distance. One or more of the couplings between the antenna assembly and the connection hub, the radiating portion and the antenna assembly, and the outer jacket and the connection hub defines a flexible configuration permitting axial movement therebetween to maintain the target axial distance between the radiating portion and the distal end member.

The present invention relates to comprehensive systems, devices and methods for delivering energy to tissue for a wide variety of applications, including medical procedures (e.g., tissue ablation, resection, cautery, vascular thrombosis, treatment of cardiac arrhythmias and dysrhythmias, electrosurgery, tissue harvest, etc.). In certain embodiments, systems, devices, and methods are provided for delivering energy to difficult to access tissue regions (e.g. peripheral lung tissues), and/or reducing the amount of undesired heat given off during energy delivery.

Transducer-based systems and methods may be configured to display a graphical representation of a transducer-based device, the graphical representation including graphical elements corresponding to transducers of the transducer-based device, and also including between graphical elements respectively associated with a set of the transducers and respectively associated with a region of space between the transducers of the transducer-based device. Selection of graphical elements and/or between graphical elements can cause activation of the set of transducers associated with the selected elements. Transducer activation characteristics, such as initiation time, activation duration, activation sequence, and energy delivery characteristics, can vary based on numerous factors. Visual characteristics of graphical elements and between graphical elements can change based on an activation-status of the corresponding transducers. Activation requests for a set of transducers can be denied if it is determined that a transducer in the set of transducers is unacceptable for activation.

A knife assembly for use with a surgical instrument includes a knife having proximal and distal ends, the proximal end including an aperture defined therein having a series of spaced apart fins extending thereacross. A knife drive rod is included and is configured to operably engage the fins to secure the knife drive rod to the knife. A retention mechanism is operably disposed at a distal end of the knife drive rod and is configured to secure the knife drive rod in engagement between the fins.

An electrosurgical apparatus for treating fluid-filled biological growths by replacing the fluid within the growth with a substance that assists in delivering treatment energy.

The treatment energy may be microwave energy or may be thermal energy derived from microwave energy. The apparatus comprises an instrument having a radiating tip portion, and a fluid delivery mechanism for transporting fluid to and from a treatment zone located around the radiating tip portion. The fluid delivery mechanism comprises a rigid insertion element arranged to extend into the treatment zone, whereby fluid can be aspirated from the treatment zone, and a substance injected into the treatment zone to replace the aspirated fluid. The injected substance has dielectric properties selected to facilitate uniform delivery of treatment energy to biological tissue in the treatment zone.

In general, devices, systems, and methods for multi-source imaging are provided.