Exemplary embodiments of system, methods and computer-accessible medium can be provided for performing feedback-controlled electromagnetic radiation (EMR)-based treatment. Some exemplary embodiments include an image acquisition system configured to detect information regarding at least one portion of a tissue, and an EMR source configured to generate an EMR beam. A controller can be provided that can be configured to (i) recognize one or more targets within the portion(s) of the tissue based upon the feedback data, (ii) locate one or more coordinates within the portion(s) associated with the target(s), and (iii) control the optical arrangement to direct the EMR beam to impact the coordinate(s).

A medical instrument includes two jaw members, at least one of which creates conditions of frustrated total internal reflection at a tissue-contacting surface when tissue is grasped between the two jaw members. The first jaw member may include an optical element having a tissue-contacting surface. The medical instrument also includes a light source that provides a light beam for sealing tissue. The light source is positioned so that the light beam is totally internally reflected from an interface between the tissue-contacting surface and air when tissue is not grasped by the jaw members. When tissue is grasped by the jaw members, at least a portion of the light beam is transmitted through that portion of the tissue-contacting surface that is in contact with the tissue. The light source may be movably coupled to a jaw member to scan the light beam and/or to change the incident angle based on optical properties of the tissue.

Certain aspects of the present disclosure provide a thermally robust laser probe assembly comprising a cannula, wherein one or more optical fibers extend at least partially through the cannula for transmitting laser light from a laser source to a target location. The probe assembly further comprises a lens housed in the cannula and a protective component press-fitted to the distal end of the cannula, wherein the lens is positioned between the one or more optical fibers and the protective component.

A laser lipolysis apparatus according to an embodiment of the present invention comprises: a first light irradiation unit for emitting a laser of a first wavelength reaching an upper region of a subcutaneous fat layer; and a second light irradiation unit for emitting a laser of a second wavelength reaching a lower region of the subcutaneous fat layer.

Provided herein is a multifunctional aesthetic system including a housing, an electromagnetic array situated in the housing and having a plurality of electromagnetic radiation (EMR) sources, each EMR source configured to generate an EMR beam having a wavelength different than that of an EMR beam generated by another of the EMR sources, a controller in electronic communication with the array to operate two or more of the EMR sources to direct the EMR beam to a treatment area, and a sensor in electronic communication with the controller for providing feedback to the controller based on defined parameters to allow the controller to adjust at least one operating condition of the multifunctional system in response to the feedback.

An apparatus and method for directing light radiation onto an intended treatment area to create an optimum power density in order to promote photobiostimulation to aid in the healing of damaged tissue in the intended treatment area. The apparatus includes a light emitting element capable of simultaneously emitting multiple beams of light radiation have multiple wavelengths onto a target surface area. A hand guide protects the hand of a user from being irradiated and a distance control element ensures a optimum distance between the light emitting element and the target surface area. The apparatus includes multiple layers of safety features to prevent thermal damage of the target surface area and to prevent leakage of the non-focussed light radiation into the atmosphere. The method includes steps for using the apparatus of the present invention.

Supercontinuum (SC) (400 nm to 2500 nm) and a microscope produce enhanced microscopic images on sub-micron to cm scale of linear (.sub.1) and nonlinear (.sub.2, .sub.3, .sub.4 . . . ) processes via resonance including linear absorption, SHG, THG, SRG, SRL, SRS, 2PEF, 3PEF, 4PEF, and inverse Raman in a microscope for 2D and 3D imaging. Images and processes in 2D and 3D arise from electronic and vibrational resonances transitions in biological and medical tissues, cells, condensed matter applications. Resonant Stimulated Raman Scattering (RSRS) is proposed to improve vibrational imaging of biomaterials by using part of SC. Quantum mechanical processes from SC for 2 and 4 photons to improve resolution and imaging using entangled photons are described. The addition of time measuring instrument like a Streak camera and the scattering coefficient .sub.s can be mapped to create images of tissue and biomaterial in 5D: Space (3D), Time, and Wavelength.

Optical energy-based methods and apparatus for sealing vascular tissue involves deforming vascular tissue to bring different layers of the vascular tissue into contact each other and illuminating the vascular tissue with a light beam having at least one portion of its spectrum overlapping with the absorption spectrum of the vascular tissue. The apparatus may include two deforming members configured to deform the vascular tissue placed between the deforming members. The apparatus may also include an optical system that has a light source configured to generate light, a light distribution element configured to distribute the light across the vascular tissue, and a light guide configured to guide the light from the light source to the light distribution element. The apparatus may further include a cutting member configured to cut the vascular tissue and to illuminate the vascular tissue with light to seal at least one cut surface of the vascular tissue.

An aesthetic treatment device uses multiple light sources, lasers or LEDs focused on the treatment area from different directions. The multiple light sources for treatment purposes could have the same wavelength or different wavelengths each optimized for a different application. Target selection is performed by a dual wavelength smart illumination system combined with an imaging system, a smart processor for target recognition and a scanning system that directs the focused light from laser sources to an automatically selected treatment area. A motorized optical system performs a dual role of: focusing the laser sources and also steering the focused light to specific locations as designated by the imaging and processing systems.

Systems, devices, and methods for identifying a target in a body using a spectroscopic feedback from the target are disclosed. An exemplary surgical feedback control system comprises a feedback analyzer configured to receive a reflected signal from a target in response to electromagnetic radiation directed at a target, and a controller in operative communication with the feedback analyzer. The controller can generate a control signal to a surgical system to perform a predetermined operation based upon the received reflected signal, including determining a composition of the target, or programming a laser setting to direct laser energy to the target.