Disclosed herein are methods and systems for treatment, such as skin rejuvenation treatment, use non-uniform laser radiation. A high-intensity portion of the laser radiation causes collagen destruction and shrinkage within select portions of the treatment area, while a lower-intensity portion of the radiation causes fibroblast stimulation leading to collagen production across other portions of the treatment area. An output beam from a laser source, such as an Nd:YAG laser, is coupled into an optical system that modifies the beam to provide a large-diameter beam having a nonuniform energy profile, comprised of a plurality of high-intensity zones surrounded by lower-intensity zones within the treatment beam. The higher-intensity zones heat select portions of the target tissue to temperatures sufficient for a first treatment (e.g. collagen shrinkage), while the lower-intensity zones provide sufficient energy for a second treatment (e.g. stimulated collagen production).

A system for the surface and subsurface delivery of therapeutic and cosmetic agents. The system includes a disposable attachable tip that can be pre-filled with medications or cosmetics and attached to hand pieces including electromagnetic and mechanical energy hand piece devices.

A multiwavelength laser-based intense light source is described having applications in incision, excision and ablation of soft tissues with minimal collateral tissue damage. The light source combines the output of a plurality of relatively low power laser sources, emitting radiation in the region of the electromagnetic spectrum bounded by approximately 350 nm to 450 nm, where the combined output may be coupled into a single fiber optic energy delivery device: a standard surgical probe. Spectral and spatial beam combining are used to produce an incoherent light source with relatively low average power at any given wavelength, but with high total power and superior M2 beam quality, targeting multiple chromophores in target tissue and tissue breakdown product chromophores for consistently high and target absorption without indiscriminant char interference throughout a surgical procedure.

The present disclosure relates to a multi-core optical fiber cable (MCF). In some embodiments, an MCF comprises a plurality of cores surrounded by a cladding and a coating surrounding the cladding, wherein a refractive index of one or more of the plurality of cores is greater than a refractive index of the cladding. The MCF further comprises a probe comprising a probe tip coupled with a distal end of the MCF and a lens located at a distal end of the probe tip. In some embodiments, the lens is configured to translate laser light from the distal end of the MCF to create a multi-spot pattern of laser beams on a target surface and a distal end of the MCF terminates at an interface with the lens.

Provided is a surgical handpiece for providing an electromagnetic cutting blade. The handpiece, comprises a body portion having an input end and an output end, a plurality of optical fibers for receiving laser energy having a wavelength within a predetermined wavelength range, wherein the optical fibers are received in the body portion at the input end and extend to the output end, and an optical fiber transition region within the body portion for arranging the plurality of optical fibers into a predetermine cutting shape at the output end, wherein laser energy transmitted from the arranged optical fibers at the output end interact with water molecules near the surgical target to generate micro-explosions that result in a cutting effect.

Certain aspects of the present disclosure provide a thermally robust laser probe assembly comprising a cannula, wherein one or more optical fibers extend at least partially through the cannula for transmitting laser light from a laser source to a target location. The probe assembly further comprises a lens housed in the cannula and a protective component press-fitted to the distal end of the cannula, wherein the lens is positioned between the one or more optical fibers and the protective component.

The present disclosure relates to a multi-core optical fiber cable (MCF). In some embodiments, an MCF comprises a plurality of cores surrounded by a cladding and a coating surrounding the cladding, wherein a refractive index of one or more of the plurality of cores is greater than a refractive index of the cladding. The MCF further comprises a probe comprising a probe tip coupled with a distal end of the MCF and a lens located at a distal end of the probe tip. In some embodiments, the lens is configured to translate laser light from the distal end of the MCF to create a multi-spot pattern of laser beams on a target surface and a distal end of the MCF terminates at an interface with the lens.

The present disclosure relates to a multi-core optical fiber cable (MCF). In some embodiments, an MCF comprises a plurality of cores, a cladding surrounding the plurality of cores, wherein a refractive index of one or more of the plurality of cores is greater than a refractive index of the cladding, and a coating surrounding the cladding, a distal end free of the coating and having a reduced diameter. The MCF also comprise an annular gap formed between the distal end of the MCF and the inner surface of the cannula, wherein the concentricity of the distal end of the MCF with the inner passage of the cannula is maintained.

Systems and methods for creating multi-spot laser light beams, multiplexing an illumination light and the multi-spot laser light beams, delivering the multiplexed light to a surgical handpiece via a multi-core optical fiber cable, and delivering the multiplexed light onto patient anatomy.

Certain embodiments of the present disclosure provide a thermally robust laser probe assembly. The probe assembly comprises a cannula through which one or more optical fibers extend at least partially for transmitting laser light from a laser source to a target location. The probe assembly also comprises a lens housed in the cannula and a protective component at a distal end of the cannula, wherein the lens is positioned between the one or more optical fibers and the protective component, and wherein the distal end of the cannula is sealed at a sealing location of the probe assembly.