A method of using a polyarticulated system associated with a vision system for automatically picking up an article situated in a zone suitable for receiving at least one article, the polyarticulated system including at least one pick-up member suitable for taking hold of an article via at least one specific zone of the article. In accordance with the invention, the method includes at least the steps of: taking an image of the article-receiving zone; processing the information resulting from the 3D image and identifying all of the specific zones that are present on the articles to be taken hold of, and that are compatible with the pick-up member(s); locating the identified compatible specific zone(s); choosing one of the located compatible specific zones and automatically defining a pick path; and taking hold of the corresponding article along the defined path.

A method for operating a transport robot includes receiving image data representative of a group of objects. One or more target objects are identified in the group based on the received image data. Addressable vacuum regions are selected based on the identified one or more target objects. The transport robot is command to cause the selected addressable vacuum regions to hold and transport the identified one or more target objects. The transport robot includes a multi-gripper assembly having an array of addressable vacuum regions each configured to independently provide a vacuum. A vision sensor device can capture the image data, which is representative of the target objects adjacent to or held by the multi-gripper assembly.