The present disclosure provides systems and methods for processing laser speckle signals. The method may comprise obtaining a laser speckle signal from a laser speckle pattern generated using at least one laser light source that is directed towards a tissue region of a subject and a reference signal corresponding to a movement of a biological material of or within the subject's body. The method may comprise computing one or more measurements using a first function corresponding to at least the laser speckle signal and a second function corresponding to the reference signal. The method may comprise generating an output signal in part based on the one or more measurements for the function space and using the output signal to aid a surgical procedure on or near the tissue region of the subject.

A surgical navigation system includes: a 3D display system with a see-through visor; a tracking system comprising means for real-time tracking of: a surgeon's head, the see-through visor, a patient anatomy and a surgical instrument to provide current position and orientation data; a source of an operative plan, a patient anatomy data and a virtual surgical instrument model; a surgical navigation image generator configured to generate a surgical navigation image with a three-dimensional image representing simultaneously a virtual image of the surgical instrument corresponding to the current position and orientation of the surgical instrument and a virtual image of the surgical instrument indicating the suggested positions and orientation of the surgical instrument according to the operative plan data based on the current relative position and orientation of the surgeon's head, the see-through visor, the patient anatomy and the surgical instrument; wherein the 3D display system is configured to show the surgical navigation image at the see-through visor, such that an augmented reality image collocated with the patient anatomy in the surgical field underneath the see-through visor is visible to a viewer looking from above the see-through visor towards the surgical field.

The invention relates to a catadioptric medical imaging system (1), in particular a surgical microscope (2). During surgery, it may be necessary to gain more information about a surgical cavity (6), in particular the type of tissue (29) at the inside walls (4) of the surgical cavity (6). To solve this problem, the catadioptric medical imaging system (1) according to the invention comprises a camera device (8) and a convex catoptric mirror (20) adapted to be inserted into the surgical cavity (6). The catoptric mirror (20) is mounted on an arm (22) and spaced apart from the camera device (8).

A three-dimensional endoscope system includes: an imaging unit configured to capture a first image and a second image having parallax with respect to each other; and an image generation unit configured to generate a display image for stereoscopic viewing by performing image processing on the first image and the second image captured by the imaging unit, wherein the image generation unit generates the display image based on the first image and a third image obtained by replacing a part of the second image with a part of the first image at a corresponding position.

An optical imaging system for imaging a target during a medical procedure, the optical imaging system involving a first camera for capturing a first image of the target, a second wide-field camera for capturing a second image of the target, at least one optional path folding mirror disposed in an optical path between the target and a lens of the second camera, and a processor for receiving the first image and the second image, the processor configured to apply an image transform to one of the first image and the second wide-field image and combine the transformed image with the other one of the images to produce a stereoscopic image of the target.

A projection system includes a light source device, an imaging unit, and a projector. The light source device includes a projection surface including a reference area, and emits light including non-visible light and visible light from the reference area. The imaging unit receives non-visible light and captures an image of the projection surface. The projector projects a projection image of visible light on the projection surface based on the captured image captured by the imaging unit.

An imaging system includes an image generating device and two reflecting mirrors. The image generating device projects a light toward a gravity direction. The two reflecting mirrors are disposed with respect to each other and one of the two reflecting mirrors is disposed with respect to the image generating device. The light projected by the image generating device forms a virtual image through the two reflecting mirrors in sequence.

Assisting robotic arm setup in a surgical robotic system using augmented reality can include capturing a live video of a user setting up a robotic arm in a surgical robotic system. A visual guide representing a target pose of the robotic arm can be rendered onto the live video, resulting in an augmented live video for guiding the arm setup. The augmented live video can be displayed to the user while the user is following the visual guide to set up the robotic arm. The captured live video can be continuously processed to determine whether the robotic arm has reached the target pose.

An imaging device includes a hollow flexible shaft having a central longitudinal axis and an imaging window therein. An optical fiber extends within the hollow flexible shaft substantially along the central axis. A distal tip of the optical fiber is attached to the hollow flexible shaft and aligned with the imaging window so as to transfer an optical coherence tomography signal through the imaging window. A handle is attached to the hollow flexible shaft configured rotate the hollow flexible shaft at speeds of greater than 1,000 rpm.

An apparatus for measuring lesion volume, for example, in laboratory animals, provides a mirror box allowing a camera to simultaneously acquire profiles of the lesion along at least two crossing axes from which accurate volume may be approximated at low cost.