A system for assisting guiding an endovascular instrument in vascular structures of an anatomical region of interest of a patient. This system includes an imaging device for capturing three-dimensional images of parts of the body of a patient, a programmable device and a viewing unit. The imaging device captures partially superposed fluoroscopic images of the region, and the programmable device forms a first augmented image, representative of a complete panorama of bones of the region, and cooperates with the imaging device to obtain a second augmented image including a representation of the vascular structures of the region. The imaging device captures a current fluoroscopic image of a part of the region, and the programmable device registers the current fluoroscopic image with respect to the first augmented image and locates and displays, on the viewing unit, an image region corresponding to the current fluoroscopic image in the second augmented image.

A method and system for facilitating identification and marking of a target in a displayed Fluoroscopic Three-Dimensional Reconstruction (F3DR) of a body region of a patient. The system includes a display and a storage device storing instructions for receiving an initial selection of the target in the F3DR, fining the F3DR based on the initial selection of the target, displaying the fined F3DR on the display, and receiving a final selection of the target in the fined F3DR via a user selection. The system further includes at least one hardware processor configured to execute said instructions. The method and instructions may also include receiving a selection of a medical device in two two-dimensional fluoroscopic images, where the medical device is located in an area of the target, and initially fining the F3DR based on the selection of the medical device.

Systems and methods for visualizing navigation of a medical device with respect to a target using a live fluoroscopic view. The methods include displaying, in a screen, a three-dimensional (3D) view of a 3D model of a target from the perspective of a medical device tip. The methods also include displaying, in the screen, a live two-dimensional (2D) fluoroscopic view showing a medical device, and displaying a target mark, which corresponds to the 3D model of the target, overlaid on the live 2D fluoroscopic view. The methods may include determining whether the medical device tip is aligned with the target, displaying the target mark in a first color if the medical device tip is aligned with the target, and displaying the target mark in second color different from the first color if the medical device tip is not aligned with the target.

A system is suggested comprising an optical sensing means and a processing unit. The optical sensing means may include an optical guide with a distal end, wherein the optical guide may be configured to be arranged in a device to be inserted into tissue in a region of interest. The processing unit may be configured to receive information of a region of interest including different tissue types as well as of a path through the tissues, to determine a sequence of tissue types along the path, to determine a tissue type at the distal end of the optical guide based on information received from the optical sensing means, to compare the determined tissue type with the tissue types on the path, to determine possible positions of the distal end of the optical guide on the path based on the comparison of tissue types, and to generate a signal indicative for the possible positions.

A spinal disorder diagnosis and treatment planning system is provided. The diagnosis and treatment planning system includes a mixed reality holographic display including at least one processor, at least one camera, at least one sensor, and being configured to acquire data points corresponding to a surface of a body adjacent to vertebral tissue. A computer database is configured to transmit imaging of the body including the vertebral tissue to the mixed reality holographic display. The mixed reality holographic display is configured to display a first holographic image of the vertebral tissue superimposed with a body image including the surface. Methods are also disclosed.

Logic may determine how to reduce bone segments. Logic may communicate one or more images to display with at least two bone segments. Logic may identify a first reduction point and a third point on a first bone segment and identify a second reduction point and a fourth point on the second bone segment. Logic may identify a fifth point on the first bone segment and a sixth point on the second bone segment. Logic may also divide the one or more images along a line or plane between the bone segments, bring the second reduction point and the associated image segment to the first reduction point, align the line or plane of the second bone segment with a line or plane of the first bone segment. Furthermore, logic may adjust alignment and record the movement of the image segments or compare original and final positions, to determine deformity parameters.

A robotic catheter procedure system includes a bedside system and a workstation. The bedside system includes an actuating mechanism configured to engage and to impart movement to a percutaneous device. The workstation includes a user interface and a control system configured to be operatively coupled to the user interface, the bedside system, and a medical imaging system. The control system is responsive to a first input and to a second input, and the user interface receives the second input from a user. The control system is configured to generate a first control signal to the medical imaging system based on the first input, and the medical imaging system captures at least one image in response to the first control signal. The control system is configured to generate a second control signal to the actuating mechanism based on the second input, and the actuating mechanism causes movement of the percutaneous device in response to the second control signal. The first input is indicative of upcoming percutaneous device movement.

A device for sealing an opening through a biologic tissue membrane against leakage. The device includes an implantable fluid sealing plug including a structural hydrogel. The fluid sealing plug is configured to be positioned at least partially within the opening through a biologic tissue such as a membrane. The fluid sealing plug is configured to increase in diameter upon absorbing a fluid, and the increase in diameter of the fluid sealing plug upon absorbing the fluid seals the opening through a biologic tissue membrane.

Various aspects of the present disclosure are directed toward apparatuses, systems, and methods for electroporation ablation. The electroporation catheter may include an electrode assembly comprising one or more ablation electrodes configured to generate electric fields proximate to target tissue in response to a plurality of electrical pulse sequences delivered in a plurality of therapy sections, and one or more mapping electrodes configured to measure cardiac electrical signals. In some embodiments, the measured electrical signals are used to create an electro-anatomical map.

The invention relates to a method and a system for determining a pose of at least one object in an operating theatre, in a reference coordinate system of a pose detection device of a surgical microscope, involving the determination of the pose of the object by way of a movably arranged microscope-external pose detection device in a first coordinate system, the first coordinate system being a coordinate system that is arranged to be stationary relative to the operating theatre, the determination of the pose of the reference coordinate system by the non-stationary microscope-external pose detection device in the first coordinate system, and the transformation of the pose of the object from the first coordinate system into the reference coordinate system of the pose detection device of the surgical microscope.