A system for constructing fluoroscopic-based three-dimensional volumetric data of a target area within a patient from two-dimensional fluoroscopic images including a structure of markers, a fluoroscopic imaging device configured to acquire a sequence of images of the target area and of the structure of markers, and a computing device. The computing device is configured to estimate a pose of the fluoroscopic imaging device for at least a plurality of images of the sequence of images based on detection of a possible and most probable projection of the structure of markers as a whole on each image of the plurality of images. The computing device is further configured to construct fluoroscopic-based three-dimensional volumetric data of the target area based on the estimated poses of the fluoroscopic imaging device.

Provided herein are systems, devices, assemblies, and methods for generating exciter signals, for example, to activate a remotely located tag. The systems, devices, assemblies, and methods find use in a variety of application including medical applications for the locating of a tag in a subject.

A computer-assisted medical device is configured and used to endoluminally navigate to a location in the gastrointestinal system and there treat certain body lumen wall areas while avoiding other body lumen wall areas. Embodiments ablate the inner mucosal layer and sub-mucosal nerve plexus of the stomach, duodenum and jejunum to effect treatment of insulin resistance and metabolic disorders, such as Type II diabetes (T2D), polycystic ovarian syndrome (PCOS), non-alcoholic steatohepatitis (NASH), non-alcoholic fatty liver disease (NAFLD), congestive heart failure (CHF) and obstructive sleep apnea (OSA). Various sensors are used to assist a clinical operator to navigate from the mouth through the pyloric sphincter and into and through the duodenum and/or jejunum. Various sensors are used to map and identify portions of the duodenum and/or jejunum. Various lumen wall ablation devices and methods are described. Various post-treatment assessments are described.

The present invention is directed to a surgical marking guide. The surgical marking guide can be configured for use in the harvest of a nipple areolar complex graft, the implant of a nipple areolar complex graft, or both the harvest and implant of a nipple areolar complex. Methods of use of the surgical marking guide are also disclosed herein.

A method and apparatus for marking a target with a radiopaque marker is disclosed. The method may include providing a radiopaque filament and inserting at least portion of the radiopaque filament into tissue. The filament may extend continuously and at last partially around a perimeter of the target so that the filament is disposed in a plurality of surgical planes to demarcate the target with the radiopaque maker.

A method and apparatus for marking a target with a radiopaque marker is disclosed. The method may include providing a radiopaque filament and inserting at least portion of the radiopaque filament into tissue. The filament may extend continuously and at last partially around a perimeter of the target so that the filament is disposed in a plurality of surgical planes to demarcate the target with the radiopaque maker.

A computer-assisted medical device is configured and used to endoluminally navigate to a location in the gastrointestinal system and there treat certain body lumen wall areas while avoiding other body lumen wall areas. Embodiments ablate the inner mucosal layer and sub-mucosal nerve plexus of the stomach, duodenum and jejunum to effect treatment of insulin resistance and metabolic disorders, such as Type II diabetes (T2D), polycystic ovarian syndrome (PCOS), non-alcoholic steatohepatitis (NASH), non-alcoholic fatty liver disease (NAFLD), congestive heart failure (CHF) and obstructive sleep apnea (OSA). Various sensors are used to assist a clinical operator to navigate from the mouth through the pyloric sphincter and into and through the duodenum and/or jejunum. Various sensors are used to map and identify portions of the duodenum and/or jejunum. Various lumen wall ablation devices and methods are described. Various post-treatment assessments are described.

An areola marker placement guide. A guide can include a superior anchor, an inferior anchor and a slidable housing located between the superior anchor and the inferior anchor. The guide can include vertical and horizontal telescoping assemblies with right and left areola markers connected to the horizontal telescoping assemblies. The guide can be used to align the areola markers such that they are equidistantly spaced from one another.

A salvage device for localizing a tissue marker clip includes an elongate handle having a metal ball connected to its distal end, and a probe connected to a distal end of the radiopaque fiducial element. A lumen extends through at least a portion of the elongate handle, the metal ball and the probe, terminating at a distal tip of the probe. A deployable tissue engagement member is housed at least partially within the lumen and connected to a proximal switch.

A method for postural independent location of targets in diagnostic images acquired by multimodal acquisitions, compensating for deformation of soft tissues due to changing posture, includes generating a transition of a digital image of the inside of a target region from a first to a second position by correlating the position of markers placed on the external surface of the target region in a digital image of the inside of the target region and in a digital representation of the external surface of the target region acquired by optically scanning the external surface; and at a later time registering the diagnostic image of the inside of the target region, transitioned into the second position, with a diagnostic image of the same target region acquired with the target region in the second position by matching a second representation of the external surface of the target region in the second position without markers with the diagnostic image of the inside of the target region transitioned into the second position.