Removable marker implants having fiducial markers disposed on multiple elongate members extend and splay laterally outward when deployed thereby providing improved 3D localization and tracking of a portion of the patient's body for stereotactic radiosurgery. Such an approach is particularly useful for tracking of the uterus during radiosurgery treatment of uterine fibroids. Such implants can include an outer sheath that contains the multiple elongate members during delivery into the portion of the body. The elongate members can be slidably disposed within the shaft and advanced into an expanded deployed position by advancement of an applicator shaft or rod within the sheath. Marker implant can also be integrally formed implants with flexible arms having fiducial markers thereon that can be constrained in a sheath for delivery and resiliently splay laterally outward when released from the shaft. Methods of delivery and deployment are also provided.

A surgical instrument comprising a shaft and a distal head extending from the shaft is disclosed. The distal head comprises a tissue drive configured to engage the tissue of a patient and move the distal head relative to the patient tissue. The tissue drive comprises, among other things, a tiltable or pivotable portion which adapts to changes in tissue thickness.

A device for attaching a localization marker to the lower jaw of an individual. The marker includes an inner face provided with two attachment lugs including an intra-oral portion having a general U-shape adapted for coming into contact with the outer face of the teeth of the lower jaw, an extra-oral portion including an attachment element for the marker, a connecting portion connecting the intra-oral portion and the extra-oral portion. The attachment element includes two recesses each adapted for receiving a respective lug of the marker, the recesses being separated by a tab adapted for being elastically deformed when one of the lugs is engaged in a respective recess so as to exert a pressure force on the lug.

Methods for manufacturing anatomical healing caps, including forming an anatomical healing cuff body for a given tooth position, the anatomical healing cuff body having a cross-section and an exterior surface so that the anatomical healing cuff body provides substantially custom filling of at least an emergence portion of a void where a natural tooth once emerged from the void or where a tooth would have emerged from a void of the given tooth position, and forming both lateral buccal and lingual handle extensions extending from the anatomical healing cuff body so that the manufactured anatomical healing cap includes a laterally extending buccal handle extension and an oppositely disposed laterally extending lingual handle extension, the buccal and lingual handle extensions being integrally formed with the healing cuff body. The healing caps can be formed using a casting jig, by machining, by 3D printing, or other suitable methods.

The present invention is directed to a system and method for performing tissue, preferably bone tissue manipulation. The system and method may include implanting markers on opposite sides of a bone, fractured bone or tissue to facilitate bone or tissue manipulation, preferably in-situ closed fracture reduction. The markers are preferably configured to be detected by one or more devices, such as, for example, a detection device so that the detection device can determine the relative relationship of the markers. The markers may also be capable of transmitting and receiving signals. An image may be captured of the bone or tissue and the attached markers. From the captured image, the orientation of each marker relative to the bone fragment may be determined. Next, the captured image may be manipulated in a virtual or simulated environment until a desired restored orientation has been achieved. The orientation of the markers in the desired restored orientation may then be determined. The desired relationship between markers may then be programmed into, for example, the detection device. Next, actual physical reduction and/or manipulation of the bone may begin. During the manipulation procedure, the orientation of the markers may be continuously monitored and when the markers substantially align with the virtual or simulated orientation of the markers in the desired restored orientation, an indicator signal is transmitted.

A method of taking a scan of a patient's oral cavity may include providing an anatomical healing cap that can be received within a subgingival void of a given tooth position. The method may also include taking a first scan (e.g., an extraoral scan) of the anatomical healing cap before seating the anatomical healing cap into the subgingival void of the given tooth position, where the anatomical healing cap is coupled to an implant disposed adjacent the anatomical healing cap. Further, the method can involve taking a second scan (e.g., an intraoral scan) of the anatomical healing cap and surrounding surfaces, and then integrating the two scans into an overall oral cavity scan. Reference points from the first scan may be used to align the second scan with the first scan, integrating the two together.

A set of three-dimensional markers enables accurate transfer of scanned dental information from an intra-oral scanner to a virtual articulator, for axis transposition in axiography and for accurate determination of individual values, such as Bennett and condylar guidance angles. The set of three-dimensional markers includes a first marker, which is aligned with a buccal face of an upper incisor, and a second marker, which is positioned outside buccal surfaces of the teeth. The first marker consists of three elements which fit together in a number of different combinations to form a single piece. For edentulous patients, a third marker and a spacer element are provided.

The present disclosure relates, in part, to a scanning sufficiency apparatus that computes whether a handheld scanning device has scanned a volume for a sufficiently long time for there to be detections and then indicate to the user that the time is sufficient in 3-D rendered voxels. Also described is a hand held medical navigation apparatus with system and methods to map targets inside a patient's body.

Systems and methods for reducing pathogens near an implant are discussed. In some cases, the methods include reducing contaminants in a portion of a patient that has an implant and that is disposed interior to a closed surface of skin of the patient. The method can further include placing a conduit in the closed surface of skin and flowing an antimicrobial fluid into that portion of the patient to contact the antimicrobial fluid with a surface of the implant and tissue adjacent to the implant. In some cases, the antimicrobial fluid is then removed from the portion of the patient having the implant. As part of this method, biofilm near the implant can be mechanically, ultrasonically, electrically, chemically, enzymatically, or otherwise disrupted. Other implementations are described.

A surgical instrument for treating the tissue of a patient is disclosed. The surgical instrument comprises a housing including a handle, a housing frame comprising a housing connector, and a drive system comprising at least one electric motor. The surgical instrument further comprises a shaft assembly releasably assembled to the housing including a shaft frame comprising a proximal connector and a distal connector, wherein the proximal connector is releasably coupled to the housing connector and a shaft drive system comprising at least one rotatable shaft operably coupled to the electric motor. The surgical instrument further comprises an end effector releasably assembled to the shaft assembly including an end effector frame comprising an end effector connector releasably coupled to the distal connector of the shaft assembly, a plurality of staple cartridges removably stored in the end effector, and a plurality of end effector drivers operably coupled to the rotatable shaft.