A preparation instrument comprising an HF-instrument with an electrode that is partially insulated by means of an insulating body, which is combined with a fluid applicator having a channel arranged in the insulating body for the application of a fluid to or into tissue. In some embodiments of the preparation instrument, the electrode is a spatula electrode which is inserted in the insulating body that does not cover sections of the surface of the electrode so that these sections may be in contact with the tissue. The insulating body preferably forms the channel wall that delimits the channel. The insulating body and the electrode may be flexible in order to adapt the form of the insulating body and the electrode, together, to the surgical task.

An assembly with a handpiece assembly configured to receive electromagnetic energy and fluid, and to selectively deliver the electromagnetic energy and/or the fluid to a target surface. The handpiece assembly includes a handpiece housing and a plurality of fluid lines extending through the handpiece housing. The plurality of fluid lines can transfer fluid from a proximal end of the handpiece assembly to a distal end of the handpiece assembly. A spray mixer can be positioned at the distal end that is coupled to fluid lines of the plurality of fluid lines. An air input port can be positioned at the proximal end that is configured to be coupled to an auxiliary air hose, and an air delivery channel can be coupled to the air input port, and can supply air to a tip of an exchangeable applicator that can be coupled to the distal end of the handpiece housing.

The invention relates to a drug and device system for the directed application of a substance into a hollow space, such as a hollow organ, or into a body cavity of a patient, i.e. a mammalian patient, in particular for use in the course of a therapeutic pneumoperitoneum. In particular, herein the present invention is for use in cancer/tumor treatment, including metastatic forms thereof, and is also directed to a kit and its use in a method of treatment, comprising the said drug and device system for the said directed application. Especially, the invention pertains to a sterile and closed prefilled drug containing (medical) device system for administering at least one pharmaceutically active substance (drug) by pressurized aerosol therapy (PAT) in a hollow organ, or preferably in a body cavity, of a patient, in particular a therapeutic pneumoperitoneum, comprising a flexible package, comprising at least one container comprising at least one pharmaceutically active substance in powder, lyophilisate, solution, liquid, gel or other form (suspension, emulsion), and being provided with breakable, an openable, or perforable cap; and a bag of liquid diluent), wherein the bag is optionally equipped with at least one drain tube provided with a closing device; and wherein the bag is equipped with a mixing tube, optionally equipped with an openable closure, and which optionally ends with a perforation device, which container is preferably a vial, syringe, single-use syringe, ampoule, phial, or bottle, comprising the said pharmaceutically active substance, and which container is provided with breakable, an openable, or perforable cap; and wherein said package is comprising at least one flexible airtight sterile casing, containing said container, preferably a vial, syringe, single-use syringe, ampoule, phial, or bottle, of the said pharmaceutically active substance, and said perforation device, said container being housed in the casing; and wherein the said container is manually maneuverable from the outside of the casing in order to be opened inside the closed casing, optionally is manually maneuverable from the outside of the casing up to a perforating position of said cap through the same perforation device; and whereupon after opening of the said container and of the said closure, and selectively mixing (i.e. dissolving, reconstituting) the at least one pharmaceutically active substance (drug) with the liquid diluent through the mixing tube, a solution of the at least one pharmaceutically active substance (drug) in the liquid diluent is provided for administering by pressurized aerosol therapy (PAT) in a hollow organ, or preferably in a body cavity of a patient.

Embodiments of an apparatus and method for sealing of tissue during uncontrollable bleeding situations during surgery are described. In one aspect, an apparatus comprises a laser unit, a laser beam delivery unit, and at least one sensor coupled to the probe of the laser beam delivery unit. The at least one sensor is configured to sense a parameter associated with the tissue or the probe. The laser unit is configured to emit a laser beam suitable for sealing an opening on a tissue. The laser beam delivery unit is detachably coupled to the laser unit, and is configured to guide and direct the laser beam to seal the opening on the tissue.

Provided is a surgical handpiece for providing an electromagnetic cutting blade. The handpiece, comprises a body portion having an input end and an output end, a plurality of optical fibers for receiving laser energy having a wavelength within a predetermined wavelength range, wherein the optical fibers are received in the body portion at the input end and extend to the output end, and an optical fiber transition region within the body portion for arranging the plurality of optical fibers into a predetermine cutting shape at the output end, wherein laser energy transmitted from the arranged optical fibers at the output end interact with water molecules near the surgical target to generate micro-explosions that result in a cutting effect.

A surgical system for providing an improved video image of a surgical site including a system controller that receives and processes video images to determine a video signature corresponding to a condition that interferes with a quality of the video images, with the system controller interacting with a video enhancer to enhance the video images from a video capturing device to automatically control the video enhancer to enhance the video images. The surgical system can also review the video images for a trigger event and automatically begin or stop recording of the video images upon occurrence of the trigger event.

A micro-sized CAP (CAP) employed to target glioblastoma tumors in the murine brain. Various plasma diagnostic techniques were applied to evaluate the physics of helium CAP such as electron density, discharge voltage, and optical emission spectroscopy. The direct and indirect effects of CAP on glioblastoma (U87MG-RedFluc) cancer cells in vitro were investigated and indicate that CAP-generated short- and long-lived species and radicals [i.e. hydroxyl radical (OH), hydrogen peroxide (H2O2), nitrite (NO2-), et al] with increasing tumor cell death in a dose-dependent fashion. Translation of these findings to an in vivo setting demonstrates that intracranial CAP is effective at preventing glioblastoma tumor growth in the mouse brain. The CAP device can be safely used in mice, resulting in suppression of tumor growth. These initial observations establish the CAP device as a potentially useful ablative therapy tool in the treatment of glioblastoma.

A surgical robotic system comprising: a robotic arm; a tool drive coupled to the robotic arm; a cannula interface configured to couple a cannula to the tool drive, the cannula interface having a fluid pathway in communication with an interior lumen of the cannula; and an insufflation pathway coupled to the robotic arm, the insufflation pathway having a distal end coupled to the fluid pathway and a proximal end coupled to a surgical insufflator.

Ultrapolar telescopic and non-telescopic electrosurgery pencils with argon beam capability which are capable of using monopolar energy in a bipolar mode for cutting and coagulation and which are also capable of using an ionized gas for cutting and coagulation.

A surgical apparatus includes: a pipe sleeve section through which gas can circulate; a first seal section provided on a proximal end side of the pipe sleeve section; a second seal section provided on an insertion opening side of the pipe sleeve section; and a sheath provided with, between the first seal section and the second seal section, a hole portion through which gas circulates.