The invention refers to an implantable sensing system comprising an electronic implant and a reading unit to obtain measurements originating at the implant or its surroundings to characterize physical and/or chemical clinical parameters of a living body. The electronic implant comprises an electronic circuit and at least two electrodes connected to the electronic circuit. The electronic circuit comprises a capacitor and a device of asymmetric conductance capable of rectifying an alternating current, both connected in series between two electrodes. An electronic component is connected in parallel with the device of asymmetric conductance, for the capacitor discharge. The capacitor, the device of asymmetric conductance and/or the electronic component, can be a transducer selected such as an operational parameter of the transducer is variable depending on a physical and/or chemical condition of a medium of a living body. The implant features a minimal invasiveness, such as it can be implanted by injection or by catheterization rather than by open surgery.

A biopotential can be measured with high accuracy without the electrodes coming into direct contact with the skin and without being affected by any motion artifact. The present invention comprises a first lead which detects a biopotential containing noise components, a second lead which is electrically isolated from the first lead and detects noise components, and a differential amplifier circuit which is input with a first signal output from the first lead and a second signal output from the second lead, and which amplifies and outputs a difference between the first signal and the second signal, wherein a value of an input impedance on the second signal side of the differential amplifier circuit is set so that the noise components detected from the second lead will have a frequency that is higher than a frequency spectrum of the biopotential.

The present disclosure provides an electronic device and method of manufacturing the same. The electronic device includes a first region, a second region, an electronic component, and a first sensing element. The second region is adjacent to the first region. The first region has a first pliability. The second region has a second pliability. The second pliability is greater than the first pliability. The electronic component is disposed at the first region. The first sensing element is disposed at the second region and electrically connected to the electronic component.

Intraocular lenses that include a central portion and one or more peripheral portions. The IOLs includes a sensor housing and a communication member, both of which are secured to the central portion.

Methods and apparatus for detection of tissue damage in patients using a medical device for an extended period of time are disclosed.

An in vivo potential measurement device includes an insulating member and an amplifier. The insulating member has an electrode. The insulating member is inserted into an organ of a living body such that an outer peripheral face of the insulating member contacts with an inner wall face of the organ at a contact site. The electrode senses electric potential at the contact site. The amplifier amplifies the electric potential to obtain output voltage. The amplifier has input capacitance Cin and input resistance Rin that satisfy Cin/Ce>0.1 and 1/(2πfCeRin)>0.1, where Ce represents capacitance of the insulating member at the contact site, and f represents frequency of the electric potential at the contact site on the inner wall face. A contact state between the outer peripheral face and the inner wall face is evaluated using the output voltage.

Methods and apparatus for detection of tissue damage in patients using a medical device for an extended period of time are disclosed.

A sensing system and method uses a sense electrode arrangement for coupling to a surface of a body such that the sense electrode arrangement and the body (and the spacing between them) define a coupling capacitance. First and second sensing circuits have different transfer functions and generate first and second outputs. These outputs are processed to determine the coupling capacitance. The electrophysiological signal being monitored is also acquired by one or both of the sensing circuits. In this way, the quality of the electrode coupling can be determined in a simple and passive manner.

A system for providing a standard electrocardiogram (ECG) signal for a human body using contactless ECG sensors for outputting to exiting medical equipment or for storage or viewing on a remote device. The system comprises a digital processing module (DPM) adapted to connect to an array of contactless ECG sensors provided in a fabric or the like. A selection mechanism is embedded into the DPM which allows the DPM to identify body parts using the ECG signals of the different ECG sensors and select for each body part the best sensor lead. The DPM may then produce the standard ECG signal using the selected ECG signals for the different body parts detected. The system is adapted to continuously re-examine the selection to ensure that the best leads are selected for a given body part following a movement of the body part, thereby, allowing for continuous and un-interrupted ECG monitoring of the patient.

Improved optical coherence tomography systems and methods to measure thickness of the retina are presented. The systems may be compact, handheld, provide in-home monitoring, allow the patient to measure himself or herself, and be robust enough to be dropped while still measuring the retina reliably.