An oximeter probe is user configurable for being in an absolute reporting mode and a relative reporting mode for measured values. The measured values for the absolute and relative modes include absolute oxygen saturation, relative oxygen saturation, absolute hemoglobin content, relative hemoglobin content, absolute blood volume, relative blood volume. The relative modes and absolute modes for determining and reporting relative or absolute hemoglobin content or relative or absolute blood volume for individual patients are beneficial when determining the efficacy of administered medications, such as epinephrine, that effect blood flow, but not oxygen saturation, in tissue, such as skin. The oximeter probe in these relative modes displays the efficacy of the administered medication as reported values for relative hemoglobin content or relative blood volume fall or rise.

Provided is a lipid measurement device which has: an irradiation unit; a light intensity detection unit; and a control unit.

Systems and methods for performing RF ablation while monitoring the procedure using low coherence interferometry (LCI) data are described. A catheter includes a distal section, a proximal section, a multiplexer, and a sheath coupled between the distal section and the proximal section. The distal section includes one or more electrodes configured to apply RF energy to a portion of a sample in contact with the electrode. The distal section also includes a plurality of optical elements configured to transmit one or more beams of exposure radiation away from the distal section of the catheter. The proximal section includes an optical source configured to generate a source beam of radiation and a detector configured to generate depth-resolved optical data. The multiplexer is configured to generate the one or more beams of exposure radiation from the source beam of radiation.

Disclosed is a polarization sensitive optical coherence tomography apparatus and control method thereof. According to the polarization sensitive optical coherence tomography apparatus and control method thereof of the present invention, the local phase delay value of each layer of a multiple of layers using Jones matrix for a birefringent material having the multiple of layers where each layers optical axis is random based on a polarized signal detected in an optical detector may be calculated. According to the present invention, a skin aging level can be accurately examined by obtaining an accurate accumulated phase delay value for a multiple of layers of birefringent material having a random optical axis.

A non-contact brain blood oxygen detecting system includes a mobile terminal device. The mobile terminal device includes a control module, a transmitting module, a receiving module and a display module. The control module is connected to the transmitting module, the receiving module and the display module, respectively. The transmitting module in the mobile terminal device is configured to emit dual-wavelength near-infrared light to a detected subject. The receiving module is configured to receive a light signal after propagation fed back by the detected subject, and to perform data conversion on the received light signal to obtain a digital signal containing blood oxygen information. The control module is configured to obtain the blood oxygen information of the detected subject according to the digital signal obtained by the receiving module. The display module is configured to display the blood oxygen information obtained by the control module.

A photoacoustic image of an object varies in contrast between a shallow portion and a deep portion according to the irradiation position of the object with respect to an ultrasonic probe. The present disclosure provides an information acquisition apparatus in which the contrast is high regardless of the depth of the region of interest. The information acquisition apparatus includes a varying unit that varies the irradiation position of the object with respect to the ultrasonic probe and controls the irradiation position according to an instruction on a condition for acquiring information on the object.

The present disclosure provides devices and methods for improved hemodynamic monitoring, including devices for characterizing hemodynamic activity within a tissue or region of interest.

Provided is a medical imaging device comprising: a color separation prism that has a dichroic film configured to split light into first light belonging to a visible light wavelength band and second light belonging to a fluorescence wavelength band; a fluorescence image sensor that is provided at an output side of the color separation prism and that is configured to image at least part of the second light belonging to the fluorescence wavelength band separated by the dichroic film; a visible light image sensor that is provided at the output side of the color separation prism and that is configured to image at least part of the first light belonging to the visible light wavelength band separated by the dichroic film; and a bandpass filter that is disposed between the color separation prism and the fluorescence image sensor, wherein the fluorescence image sensor and the visible light image sensor are arranged such that an optical path difference between an optical path length of a fluorescence optical path for the second light imaged on the fluorescence image sensor via the color separation prism and an optical path length of a visible light optical path for the first light imaged on the visible light image sensor via the color separation prism corresponds to an amount of a shift between a fluorescence imaging position and a visible light imaging position, the shift being generated by an imaging lens positioned at an input side of the color separation prism, and wherein the fluorescence imaging position is an imaging position of filtered second light, which results from passing the second light through the bandpass tiller, such that tlic amoiuu of shifl is based on the filtered second light.

The invention comprises a method and apparatus for selecting optical pathways sampling a common tissue position, such as a lateral mean range in the dermis, of a person for analysis in a noninvasive analyte property determination system, comprising the steps of: probing skin with a range of illumination zone-to-detection zone distances with at least two wavelength ranges, which optionally overlap, and selecting, using a metric, illumination zone-to-detection zone distances having mean optical pathways probing the common tissue layer, such as without the mean optical pathways entering the subcutaneous fat layer of the person. Optionally, the skin tissue layers are modulated and/or treated via tissue displacement before and/or during data collection.

The invention comprises a method and apparatus for sampling skin of a person as a part of noninvasive analyte property determination system, comprising the steps of: providing an analyzer, comprising: sources and at least three detectors at least partially embedded in a probe housing, the probe housing comprising a sample side surface, the detectors including: a range of differing radial distances from a first illumination zone; repetitively illuminating an illumination zone of the skin with photons in a range of 1200 to 2500 nm; detecting portions of the first photons with the at least three detectors; and using signals from the at least three detectors and a metric, respectively classifying the skin into a first, second, and third tissue state, the radial distances of the at least three detectors differing from each other by greater than ten percent.