The invention comprises a method and apparatus for sampling a common tissue volume and/or a common skin layer skin of a person as a part of noninvasive analyte property determination system, comprising the steps of: providing an analyzer, comprising at least three detectors at least partially embedded in a probe housing, the probe housing comprising a sample side surface, the detectors including a first and second range of detection zones of differing radial distances from a first illumination zone and second illumination zone, respectively coupled to separate sources; repetitively illuminating the illumination zones of the skin with photons in a range of 1200 to 2500 nm; and detecting portions of light from the sources with the at least three detectors, the detectors positioned on a common line with the sources.

The invention comprises a method and apparatus for sampling a common tissue volume and/or a common skin layer skin of a person as a part of noninvasively determining an analyte property with an analyzer including: a set of detectors at least partially embedded in a probe housing, the probe housing comprising a sample side surface, the detectors including a first and second range of detection zones of differing radial distances from a first illumination zone and second illumination zone, respectively coupled to separate sources, with surface paths between the sources and detectors overlapping a common skin area during use.

Source light having a range of optical wavelengths is generated. The source light is split into sample light and reference light. The sample light is delivered into a sample, such that the sample light is scattered by the sample, resulting in signal light that exits the sample. The signal light and the reference light are combined into an interference light pattern having optical modes, each having a direct current (DC) component and at least one alternating current (AC) component. Different subsets of the optical modes of the interference light pattern are respectively detected, and analog signals representative of the optical modes of the interference light pattern are output. Pair of the analog signals are subtracted from each other, and differential analog signals are output. The sample is analyzed based on the differential analog signals.

An optical vital signs sensor configured to measure or determine vital signs of a user comprises a light source configured to generate a light beam having an angular range of angles of incidence. The light beam is directed towards the skin of the user. A photo detector is provided and is configured to detect light which is indicative of a reflection of the light beam from the light source in or from the skin of the user. The light source and the photo detector are arranged adjacent to each other and on the same side of the skin of the user. A light shaping unit is configured to shape the light beam of the light source before the light beam enters the skin by limiting the angular range of angle of incidence to less than 20.

The present disclosure generally relates to wearable devices and methods for measuring a photoplethysmographic (PPG) signal. The wearable devices and methods described herein are capable of obtaining PPG signals by employing a PPG sensor array configured to receive light at angles associated with a high perfusion index. Viewing components may be coupled to the PPG sensor array to effect transmission of light at these preferential angles.

The present invention provides a uterus OCT catheter, comprising: a catheter body; the catheter body comprises an outer sleeve, an OCT imaging catheter and a Luer connector; the outer sleeve is provided with an exit window; the reflecting surface of the reflecting prism in the OCT imaging catheter faces the exit window. The present invention further provides a uterus OCT equipment with pull-back function, comprising a pull-back device and the catheter body, the pull-back device comprises a first housing, a driving connector, a fixing sleeve and a catheter fixing tube. The invention adopts the way that the outer sleeve wraps the OCT imaging catheter to increase the overall strength and diameter; a pull-back device is adopted, the pull-back process is stable and in uniform speed, and can effectively prevent complications during human operation and damage to human tissue during pull-back process.

Disclosed is an optical probe of an optical coherence tomography (OCT) system according to an exemplary embodiment of the present disclosure. The optical probe of the OCT system includes: an optical fiber receiving light generated from a light source and transferring the received light to a plurality of lenses and receiving light reflected from tissue from the plurality of lenses and transferring the received light to an optical coherence system; a plurality of lenses including a first lens positioned at a distal end of the optical fiber and a second lens positioned at a predetermined point in a longitudinal direction of the optical fiber; and a sheath capable of accommodating the optical fiber therein.

A combined OCT/pressure sensor system includes an optical cable comprising a single-mode core and a multi-mode core. An OCT optical imaging sensor near a distal end of the optical cable can be inserted into a lumen of a living being. First light exiting a distal end of the single-mode core illuminates an interior of the lumen. The OCT optical imaging sensor acquires image information about the interior of the lumen and transmits an optical signal carrying the image information into the distal end of the single-mode core, toward a proximal end of the single-mode core. An optical pressure sensor attached near the OCT optical imaging sensor receives second light from the distal end of the optical cable, senses ambient pressure within the lumen and transmits an optical signal indicative of the ambient pressure into a distal end of the multi-mode core, toward a proximal end of the multi-mode core.

An oximeter probe determines an oxygen saturation for the tissue and determines a quality value for the oxygen saturation and associated measurements of the tissue. The quality value is calculated from reflectance data received at the detectors of the oximeter probe. The oximeter probe then displays a value for the oxygen saturation with the error value to indicate a quality level for the oxygen saturation and associated values used to calculate oxygen saturation.

Described herein are embodiments of an approach to diagnosing pancreatic cystic lesions using light scattering spectroscopy. In some embodiments, the approach includes an apparatus including a spatial gating probe to isolate light reflected by the epithelial tissue of the internal cyst surface using spatial gating. In some further embodiments, the apparatus includes a scanning fiber probe that is capable of rotational and linear motion in order to scan the entire internal surface of the cyst. Use of such an approach may be advantageous to improve the accuracy of diagnosing pancreatic cystic lesions as cancerous, precancerous, or benign.