A system for in-vivo monitoring of intracranial pressure is provided. The system includes a probe and a controller. The probe includes optical emitters and optical detectors. The optical detectors detect light emitted by the optical emitters generate signals representative of the detected light. The controller includes memory and processor. The controller connects to the probe to energize the optical emitters and receiving signals from the optical detectors. The system may include modelling, extraction, and pressure prediction modules. The modelling module can relate intracranial pressure to features of an optical signal representative of a degree to which light input into a subject's skull is absorbed by the subject's brain. The extraction module can extract signal features from a signal derived from the optical signals output by the detectors. The pressure prediction module can input the signal features into the modelling module and output an indication of intracranial pressure.

Provided are a measurement support device, an endoscope system, a processor for an endoscope system, and a measurement support method capable of easily and highly accurately measuring the size of a subject. In the measurement support device related to one aspect of the invention, the position of a spot by measurement auxiliary light is measured, and information indicating the actual size of a subject is acquired on the basis of the measurement result to create and display a marker. Moreover, an optical axis of the measurement auxiliary light has an inclination angle that is not 0 degrees with respect to an optical axis of the imaging optical system in a case where the optical axis of the measurement auxiliary light is projected on a plane including the optical axis of the imaging optical system.

The present disclosure relates to a medical microscope field. A stereo microscope connected to an optical coherence tomography (OCT) unit for forming a tomographic image of a target object includes an objective lens unit including a plurality of lenses each having an aperture of a predetermined size, a pair of first magnification lens units each including a plurality of lenses having a pair of magnification lens apertures positioned within the aperture of the objective lens unit, a second magnification lens unit including a plurality of lenses having an OCT aperture disposed separately from the pair of magnification lens aperture within the aperture of the objective lens unit, and a light delivery unit configured to receive light from the OCT unit and deliver the light to the second magnification lens unit and configured to deliver light received from the second magnification lens unit to the OCT unit.

An oximeter probe determines an oxygen saturation for the tissue and determines a quality value for the oxygen saturation and associated measurements of the tissue. The quality value is calculated from reflectance data received at the detectors of the oximeter probe. The oximeter probe then displays a value for the oxygen saturation with the error value to indicate a quality level for the oxygen saturation and associated values used to calculate oxygen saturation.

A live subject tissue detection device includes a light source configured to emit light onto the tissue of a subject, a photodetector configured to receive light reflected from the tissue and light reflected from the blood flow, wherein the light reflected from the blood flow has a Doppler shift relative to the light reflected from the tissue, and generate a high frequency Doppler signal based on the Doppler shift, a detection circuitry configured to receive the high frequency Doppler signal from the photodetector and convert the high frequency Doppler signal into a low frequency signal, and at least one processor configured to compute parameters of the low frequency signal, compare the parameters of the low frequency signal to respective reference values, and determine a presence of live tissue based on the comparison.

A device is for estimating a blood pressure of a user by a combination of an acoustic mode employing acoustic emitters and acoustic detectors and an optical mode using light sources and photodetectors forming source—detector pairs. The device includes an acoustic selection unit to determine the pertinent acoustic emitter—acoustic detector pair as well as an optical selection unit to determine the pertinent light source—photodetector pairs.

A method of assessment of renal function by monitoring a time-varying fluorescence signal emitted from a fluorescent agent from within a diffuse reflecting medium with time-varying optical properties is provided that includes using a renal monitoring system comprising at least one light source, at least one light detector, at least one optical filter, and at least one controller to provide a measurement data set comprising a plurality of measurement entries, each measurement data entry comprising at least two measurements obtained at one data acquisition time from a patient before and after administration of the fluorescent agent.

A method, system, apparatus, and/or device to determine a condition of a user using a wearable device with a miniaturized spectrometer. The method, system, apparatus, and/or device may include: a band configured to extend at least partially around a body part of a user, the body part comprising an internal feature within the body part; a light source embedded in the band, where the light source is configured to emit light into the body part as the user wears the band; a collimator; an optical filter; and an optical sensor, where the collimator, optical sensor, or the optical filter are arranged together to form a stack embedded in the band.

The present disclosure generally relates to wearable devices and methods for measuring a photoplethysmographic (PPG) signal. The wearable devices and methods described herein are capable of obtaining PPG signals by employing a PPG sensor array configured to receive light at angles associated with a high perfusion index. Viewing components may be coupled to the PPG sensor array to effect transmission of light at these preferential angles.

Systems and methods for path length selected diffuse correlation spectroscopy (PLS-DCS) are disclosed. The systems and methods are suitable for measuring dynamics of a target medium. The systems and methods can utilize light sources having a coherence length that is shorter than a path length distribution of the target medium and can utilize a reference optical path to interferometrically detect PLS-DCS signals. The coherence length and reference path length can be selected to provide sensitivity to portions of the target medium that correspond to a desired path length distribution.