Intravascular devices, systems, and methods are disclosed. In some instances, the intravascular device is a guide wire with electrical conductors embedded within a core wire. In some instances, the electrical conductors are coupled to conductive bands adjacent a proximal portion of the guide wire and a sensing element adjacent a distal portion of the guide wire. Methods of making, manufacturing, and/or assembling such intravascular devices and associated systems are also provided.

A flexible photonic skin is provided, including a functional layer, an adhesive layer used for fixing the functional layer and made of hypoallergenic polyvinyl ethyl ether, and a packaging layer made of a polyurethane semi-transparent film and adhered to the adhesive layer, which are arranged successively from the top down, wherein the functional layer consists of two electrodes located on two sides and used for acquiring electrocardiographic signals of a human body, and a polymer-based photonic integrated chip located between the two electrodes and used for acquiring body temperature, pulse, blood pressure and blood glucose signals of the human body; and, the polymer-based photonic integrated chip processes and outputs the acquired electrocardiographic signals of the human body as well as the body temperature, pulse, blood pressure and blood glucose signals of the human body.

The present disclosure includes a connector assembly that is a part of a sensor assembly for collecting patient physiological data. The connector assembly can include a first connector tab with catches, a second connector tab with openings, a retainer with pins, and a circuit board coupled to a cable. Each of the pins of the retainer can include a detent that can engage one of the catches of the first connector tab. The pins can extend through the openings of the second connector tab so that the retainer is coupled to the first connector tab by the detents engaging the catches. The first and second connector tabs can thereby be coupled together to support the circuit board and the cable between the first and second connector tabs.

A sensor probe has a connector and the connector's corresponding receptacle on a console have security mechanisms that ensure that the connector and the receptacle are properly connected and mated. The connector and receptacle can have physical security features that block insertion of the connector into the receptacle if they are not aligned in a proper orientation. The console can also include a software security feature that allows optical measurements from the sensor probe only if the connector of the sensor probe and receptacle on the console are connected properly. An adapter can also be used to convert a conventional receptacle mounted on a console into a receptacle with security features.

A sensor component for use in a system for measuring concentration of analytes in fluid in a fluid line comprises one or more sensing elements having an optical property that varies with the concentration of the analytes, and engages with the fluid line such that the sensing elements are exposed to the fluid. The sensor component comprises a connector connecting to one or more optical waveguides, and transmits light between the waveguides and the sensing elements. The sensor component comprises one or more of a sampling port configured to provide fluidic access to the fluid line, a data storage medium storing data representing information about the sensor component, and a reflective element. Where it comprises a reflective element, the sensor component transmits light between the waveguides and the reflective element on a separate optical path from an optical path between the waveguides and the sensing elements.

Systems and methods for multi-modal imaging using an endoscope having an instrument channel, where the imaging is achieved without using the channel, are disclosed. The systems can include a multi-modal imaging paddle housing couple to a distal end of the endoscope. The housing can receive at least two imaging probes. The imaging probes can be an angle-resolved low-coherence interferometry probe (a/LCI) and an optical coherence tomography (OCT) probe. The housing can be scaled and positioned to be visible via the endoscope camera. The system and method can include locating the housing in a region of interest using the endoscope camera, acquiring OCT measurements to identify targets, and then acquiring a/LCI measurements at the identified targets.

An electrode for a user wearable apparatus; the electrode comprising: a conductive part comprising conductive material, wherein the conductive part is configured to provide electrical connection to electronic components of the user wearable device, and an opening configured to provide an optical connection to electronic components of the user wearable apparatus through the electrode.

A system comprising a multi-sensor catheter for monitoring of a cardiac hemodynamic condition, e.g. heart failure, is disclosed. The multi-sensor catheter comprises multi-lumen catheter tubing comprising first and second optical pressure sensors, and their respective optical fibers and connectors. For right heart and pulmonary artery catheterization, a flow-directed multi-sensor catheter comprises a guidewire lumen, an inflatable balloon tip, and sensor locations are configured for placement of a sensor in each of the right atrium and pulmonary artery, for measurement of central venous pressure in the right atrium and a pulmonary artery pressure. An optical fiber for oximetry may be included. The outside diameter is small enough for insertion through a vein of the arm. For monitoring of a left atrial shunt, sensors of a multi-sensor catheter are configured for measuring pressures upstream and downstream of the shunt, e.g. in the left and right atria, or left atrium and coronary sinus.

A connector system includes a male connecter including a male housing defining a recess and a plurality of pins arranged within the recess; and a female connector including a female housing configured to be insertable into the recess of the male housing. The female housing includes: front and back portions; a pair of longitudinal sides that extend from the front portion to the back portion; a planar side that extends from the front portion to the back portion, the planar side connecting first ends of the pair of longitudinal sides; a rounded side that extends from the front portion to the back portion, the rounded side connecting second ends of the pair of longitudinal sides; a front surface defined at the front portion by the pair of longitudinal sides, the planar side, and the rounded side; and a plurality of sockets formed at the front surface.

A wearable module assembly for an optical measurement system includes a first wearable module, a second wearable module, and a connector. The first and second wearable modules each include a light source configured to emit a light pulse toward a target within a body of a user, a housing that houses the light source and the plurality of detectors and includes a substantially hexagonal surface that faces a surface of the body of the user when the wearable module assembly is worn by the user, and a plurality of detectors each positioned at a fixed distance from the first light source and each configured to detect a set of photons included in the light pulse after the set of photons are scattered by the target. The connector directly connects the first wearable module and the second wearable module at mutually-facing side surfaces of the respective housings.