Antibacterial coatings and methods of making the antibacterial coatings are described herein. A first branched polyethylenimine (BPEI) layer is formed and a first glyoxal layer is formed on a surface of the BPEI layer. The first BPEI layer and the first glyoxal layer are cured to form a crosslinked BPEI coating. The first BPEI layer can be modified with superhydrophobic moieties, superhydrophilic moieties, or negatively charged moieties to increase the antifouling characteristics of the coating. The first BPEI layer can be modified with contact-killing bactericidal moieties to increase the bactericidal characteristics of the coating.

Antibacterial coatings and methods of making the antibacterial coatings are described herein. A first branched polyethylenimine (BPEI) layer is formed and a first glyoxal layer is formed on a surface of the BPEI layer. The first BPEI layer and the first glyoxal layer are cured to form a crosslinked BPEI coating. The first BPEI layer can be modified with superhydrophobic moieties, superhydrophilic moieties, or negatively charged moieties to increase the antifouling characteristics of the coating. The first BPEI layer can be modified with contact-killing bactericidal moieties to increase the bactericidal characteristics of the coating.

A medical device intended for contact with living tissue comprises a substrate having a surface, which surface comprises a layer comprising gallium oxide. A layer comprising a gallium oxide has been shown to inhibit biofilm formation on the surface of the medical device, which may reduce the risk for infection e.g. around a dental implant. A method of producing the medical device comprises: a) providing a substrate having a surface; and applying a gallium compound onto said surface to form a layer, preferably using a thin film deposition technique.

Method for the surface treatment of a dental implant or a prosthetic component made out of titanium or a titanium alloy, which enables an outer surface of the implant or the prosthetic component to be obtained with a notable capacity to prevent bacterial adhesion and offer a better aesthetic finish. This method comprises the steps of providing an outer surface of the implant or the prosthetic component with a surface roughness, and applying an anodizing treatment on the implant or the prosthetic component, smoothing the roughness and generating nanopores on this outer surface of the implant or the prosthetic component. The invention also relates to a dental implant or a prosthetic component made out of titanium or a titanium alloy, which comprises an outer surface that is rough and has nanopores.

An implant system and a method of forming the implant system including an implant to be implanted into living bone. The implant includes titanium. The implant includes a first surface geometry on a first portion of a surface of the implant and a second surface geometry on a second portion of the surface of the implant. The first surface geometry includes at least a submicron topography including tube-like structures and the second surface geometry includes a first micro-scale topography, a second micro-scale topography superimposed on the first topography, and a submicron topography superimposed on the first and second micro-scale topographies, the submicron topography including the tube-like structures.

The present disclosure provides a dental implant configured to be inserted in a hole in jaw bone and to be at least partially situated in the bone tissue when implanted and includes: a coronal region, an apical region, a longitudinal axis extending from the coronal region of the dental implant to the apical region of the dental implant; an implant surface configured to form an interface between an implant material and the oral environment/surrounding tissue and a surface layer formed on at least part of the implant surface, the surface layer including crystalline titanium oxide in the anatase phase and wherein the surface area roughness Sa and the pore size of the implant surface on which said surface layer is formed increase from the coronal region toward the apical region of the dental implant along the longitudinal axis.

An implant system and a method of forming the implant system including an implant to be implanted into living bone. The implant includes titanium. The implant includes a first surface geometry on a first portion of a surface of the implant and a second surface geometry on a second portion of the surface of the implant. The first surface geometry includes at least a submicron topography including tube-like structures and the second surface geometry includes a first micro-scale topography, a second micro-scale topography superimposed on the first topography, and a submicron topography superimposed on the first and second micro-scale topographies, the submicron topography including the tube-like structures.

To provide a a glass composition which can be used for a dental porcelain or a dental ceramics coloring material, and has low temperature meltability, acid resistance and preservation stability under the humid environment which are required for a dental porcelain or a dental ceramics coloring material, and a dental porcelain and dental ceramics coloring material which contain the glass composition of the present disclosure. To provide a low melting glass composition with softening point (Ts) less than 600 C. comprising as a component; SiO.sub.2: 55.0 to 75.0 wt. %, B.sub.2O.sub.3: 6.1 to 12.0 wt. %, Al.sub.2O.sub.3: 2.0 to 8.0 wt. %, ZnO: 2.0 to 8.5 wt. % and two or more kinds of alkali metal oxide: 10.5 to 20.0 wt. %.

Custom dental prosthesis or implants each individually designed and manufactured to replace nonfunctional natural teeth positioned in a jawbone of a specific pre-identified patient are provided. An example dental prosthesis/implant includes a dental implant body having a prosthesis interface formed therein to receive an occlusal-facing dental prosthesis component. The prosthesis interface has a custom three-dimensional surface shape positioned and formed to create a form locking fit with respect to the occlusal-facing dental prosthesis component when positioned thereon.

The present invention relates to an endosseous implant assembly adapted for treatment of peri-implantitis. The implant assembly comprises an implant core body configured to receive and couple with implant insert structures that potentially facilitate treatment of peri-implantitis.