A mouthpiece for a dental cleaning device comprises a supporting structure configured to encompass a plurality of teeth of a dental arch. The supporting structure has an inner surface facing a tooth surface. At least one brushing chamber is provided at the inner surface side. The brushing chamber comprises a flexible wall part being deformable by pressurizing or depressurizing the brushing chamber. Bristles extend externally from the flexible wall part. In a method of brushing teeth, a plurality of teeth is encompassed by the mouthpiece, and the at least one brushing chamber is alternatingly pressurized and depressurized.

A dentifrice dispenser for dispensing a dentifrice onto a J-shaped or U-shaped mouthpiece is configured for simultaneously encompassing and cleaning a plurality of dental positions with the dispensed dentifrice and with cleaning elements provided on or in the mouthpiece. The dispenser comprises a dispenser duct work having an inlet and a manifold. The manifold comprises a multiple of outlet openings configured for dispensing dentifrice. The duct work is configured for passing dentifrice from the inlet to the outlet openings. The outlet openings are distributed along a J-shaped or U-shaped curvature and debouch towards and/or along the curvature, which matches at least part of a dental arch such that the outlet openings can dispense dentifrice simultaneously on a multiple of locations along the curvature, the multiple of locations corresponding to the multiple of outlet openings.