A coated urinary catheter or urinary stent device includes a urinary catheter or stent which, in a deployed position, includes or defines a protective surface area and a protected surface area and a coating upon at least a portion of the protective surface area. The coating includes a lubricant and an antimicrobial and/or pH buffering material. The device is configured such that, upon application of negative pressure to the catheter or stent, tissue of a urinary tract of a patient conforms or collapses onto the protective surface area and is thereby prevented or inhibited from occluding one or more protected drainage holes, ports or perforations of the catheter or stent.

An implant with one or more sensors to measure fluid and tissues of the patient. The sensor may comprise a mechanical sensor configured to measure growth of a tissue such as BPH or a tumor. Alternatively or in combination, the implant may comprise one or more electrodes to stimulate tissue related to urinary urgency or male sexual function.

A dilating device for the prostatic urethra comprising: Prostatic implant includes independently actuatable distal retractor incorporating and proximal retractor. Retractors may be connected via a spine member. System and method include implant manipulator detachably connected to implant, for manipulating and forcing implant into close proximity, for delivery into subject.

A Coude catheter insures proper drainage and reduces tissue damage by using a loop section having an open passageway positioned on a proximal end of the catheter to adjust the catheter.

Systems, instruments, methods, and compositions are described involving removing a portion of the epidermis within a donor site on a subject, and harvesting dermal plugs within the donor site. An injectable filler is formed by mincing the dermal plugs. The injectable filler is configured for injecting into a recipient site on the subject.

A urethral-implant is configured to be implanted within a restricted location of a urethra. The urethral-implant forms at least one closed-shape by coiling ends of a single wire section on each other. The closed-shape includes a distal section, a proximal section and two lateral sections extending between the proximal section and the distal section. The closed-shape exhibits an expanded configuration and is foldable into a compressed configuration. The urethral-implant further is configured to extend from the compressed configuration to the expanded configuration so that the distance between wire sections increases, relative to the distance between wire sections in the compressed configuration. The urethral-implant applies continuous pressure on surrounding tissue thereby applying continuous radial pressure on at least one of a urethral wall and tissue surrounding the urethral wall. The radial pressure is sufficient to cause either a widening effect, extending a urinal passage or inducing infarction.

The presently described stent-graft includes a stent frame forming a cavity and frame wires extending around the stent frame perimeter. The stent frame is formed such that the cavity cross sectional area decreases along a first length of a flow restricting section to a cavity minimum cross sectional area and increases along a second length of the flow restricting section. The first length extends from a cavity proximal cross sectional area to the cavity minimum cross sectional area and the second length extends from the cavity minimum cross sectional area to a cavity distal cross sectional area. When placed within a patient's aorta, the stent-graft may help the treatment of congestive heart failure by increasing blood flow to the kidneys. The provided stent-graft may also be adapted for placement within a patient's urethra to help the treatment of urinary incontinence.

A device and a method for treatment of a urethra that is constricted due to benign prostatic hyperplasia (BPH) are provided, including a delivery tool (101) advanced to a location in an area of the urethra that is to be treated. The delivery tool (101) includes an expandable element (400) that expands within the urethra such as to enlarge the urethra, a tissue cutter (412) that forms a cut in the urethra, subsequently to the expandable element expanding to dilate the urethra, and an implant (410) that maintain the urethra in a dilated state. The implant (410) includes a shape-memory material and is shaped to define two end sections and a middle section (1202) disposed between the two end sections. The shape memory-material is shape set such that in an unconstrained configuration of the implant (410), the middle section (1202) is substantially straight. Other embodiments are also described.

An incising implant for creating incisions in the prostatic urethra of a subject, the implant including at least two closed-shaped wires, each of the wires having a proximal section, a distal section and two longitudinal sections extending between the proximal section and the distal section, each of the closed-shaped wires being elastic thereby being compressible into a compressed configuration, each of the longitudinal sections of each of the wires being adjoined with another longitudinal section of another one of the wires.

A catheter configured to be deployed in a urinary tract of a patient includes a proximal portion configured to pass through a percutaneous opening and a distal portion including a retention portion. The retention portion is configured to be deployed in a kidney, renal pelvis, and/or bladder of the patient. The retention portion includes one or more protected drainage holes, ports or perforations and is configured, when deployed, to establish an outer periphery or protective surface area that inhibits mucosal tissue from occluding the one or more protected drainage holes, ports, or perforations upon application of negative pressure through the catheter.