Embodiments of this invention generally relate to systems and methods for optical treatment and more particularly to non-invasive refractive treatment method based on sub wavelength particle implantation. In an embodiment, a method for optical treatment identifies an optical aberration of an eye, determines a dopant delivery device configuration in response to the optical aberration of the eye, wherein the determined dopant delivery device is configured to impose a desired correction to the eye to mitigate the identified optical aberration of the eye by applying a doping pattern to the eye so as to locally change a refractive index of the eye.

Corneal implant (1) designed for correcting irregularities of the corneal curvature of a subject, the implant (1) having a generally dome-shaped structural body (2) configured to impose a regular curvature to the corneal portions designed to be in contact with the implant, wherein the structural body comprises an outer peripheral ring (10) and an inner reticular structure (20), wherein the inner reticular structure (20) comprises at least one first and one second series of beams (21, 22) intersecting each other, the beams (21) of the first series having a respective first end (31) connected to the outer peripheral ring (10), wherein the total area of void portions (24) within the meshes of the reticular structure (20) is between 50 and 99.9% of the surface area of the reticular structure (20).

The invention relates to an apparatus for changing the refractive power of the cornea (1), in particular for correcting hyperopia or presbyopia, exhibiting injection means (13, 15) having at least one hollow needle (15) for injecting at least one optically transparent filling material having a predetermined refractive index into an intrastromal corneal pocket (7), characterized by a controllable injection drive (17) that is coupled at least indirectly to the injection means (13, 15) and is designed for changing an amount, to be injected, of the at least one filling material; a device for optical coherence tomography (OCT) (19) that is designed for monitoring the area of the corneal pocket (7) by means of measurement of depth profiles of the cornea (1) on a repeatedly cycled-through scan pattern; and a computing unit (21) that is designed and/or configured to determine from the measurement data of the OCT device (19) at least the radius of curvature of the front (3) of the cornea (1) keeping pace temporally with the repetitions of the scan pattern cycle during the injection, wherein the computing unit (21) is designed and/or configured to control the injection drive (17) for changing the injected amount of the at least one filling material, and namely on the basis of the radius of curvature of the front (3) of the cornea (1) and/or such until a predetermined target criterion is fulfilled.

The present invention includes a device for effecting deformation of a sclera of an eye, including an expandable, mesh tube having holes dispersed through an entire surface thereof and with first and second tapered ends, and inserted unexpanded to deform the sclera when expanded. A central portion is intrascleral, with the first and second tapered ends external to the sclera on top of an intact scleral surface to deform during expansion, and simultaneously causes the sclera to be deformed so that the sclera moves towards the inside of the eye while simultaneously causing the sclera to move towards the outside of the eye. The mesh tube includes struts, connecting points of the struts are of different sizes, the first and second tapered ends and the connecting points within the tapered ends are thicker than the connecting points of the mesh tube, and the mesh tube includes fixation tabs.

An injector of intracorneal segments has a disposable segment holding head comprising a lancet (36) formed with a housing closed by the lid (37) wherein a sterilized corneal segment (11) is housed, behind which there is a needle (26) longitudinally slidable under the action of a trigger (31) and a spring (32). The head also has a manual selector (38) to deflect the needle to place the segment at 90° of the head to the right or left of a channel made in the cornea for injection. The segment pre-installed in the head is provided with recesses formed by knurling (16) on its outer chord (14) where it couples to the needle for the push.

Corneal transplant procedures may involve suturing an implant of healthy corneal tissue to a recipient cornea. The sutures may cause unwanted deformation of the corneal implant and the recipient cornea. A supporting structure may be embedded into the corneal implant to enhance the stability of the corneal implant and the recipient cornea and to reduce the likelihood of unwanted deformation when the corneal implant is sutured to the recipient cornea. According to one embodiment, a corneal implant includes donor corneal tissue extracted from a donor cornea. The donor corneal tissue includes an interior channel formed at a depth below an anterior surface. The corneal implant includes a supporting structure formed from non-tissue material and positioned in the channel.

Embodiments of this invention generally relate to systems and methods for optical treatment and more particularly to non-invasive refractive treatment method based on sub wavelength particle implantation. In an embodiment, a method for optical treatment identifies an optical aberration of an eye, determines a dopant delivery device configuration in response to the optical aberration of the eye, wherein the determined dopant delivery device is configured to impose a desired correction to the eye to mitigate the identified optical aberration of the eye by applying a doping pattern to the eye so as to locally change a refractive index of the eye.

An intracorneal ring made of a polymer compatible with corneal metabolism such as polymethyl methacrylate (PMMA) in cooperation with a corneal graft for adjusting the topography and increasing the thickness of cornea. The ring is a full circle with two spherical or aspherical side surfaces defining its thickness, and an inner and an outer rim defining its width. A plurality of holes distributed around the ring pass through the thickness. A donor corneal graft sutured to the ring via the holes and stretched flat by the suture, fills the inside of the ring. The integrated ring, graft, and suture called as ring graft is inserted in the cornea stroma using superior scleral tunnel incision to correct the shape of the cornea and improve visual acuity. The ring supports the graft circumferentially and promotes its bonding with stroma. The supported graft reshapes and regenerates the cornea. The invention is applicable to treating mild to severe keratoconus, ectasia and other cornea disorders. The ring graft also increases the thickness and strength of cornea, which additionally slows down the progress of keratoconus. There is post operation potential for further visual acuity improvement with refractive correction procedures such as customized PRK. The ring has an outer rim diameter of nearly the normal diameter of cornea and acts as an auxiliary limbus providing additional support to the cornea.

A mask configured to be implanted in a cornea of a patient to increase the depth of focus of the patient includes an anterior surface, a posterior surface, and a plurality of holes. The anterior surface is configured to reside adjacent a first corneal layer. The posterior surface is configured to reside adjacent a second corneal layer. The plurality of holes extends at least partially between the anterior surface and the posterior surface. The holes of the plurality of holes are configured to substantially eliminate visible diffraction patterns.

An optical device comprising an optical hydrogel with select regions that have been irradiated with laser light having a pulse energy from 0.01 nJ to 50 nJ and a wavelength from 600 nm to 900 nm. The irradiated regions are characterized by a positive change in refractive index of from 0.01 to 0.06, and exhibit little or no scattering loss. The optical hydrogel is prepared with a hydrophilic monomer.