A temporary keratoprosthesis, a corneal transplant suturing jig, a temporary endoprosthesis, methods of using the same, and kits comprising the same. The temporary keratoprosthesis and corneal transplant comprise grooves into which sutures are located during ophthalmological surgery such that the sutures are prevented from migrating and/or obscuring a view into the eye during surgery. The temporary keratoprosthesis, corneal transplant suturing jig, and temporary endoprosthesis are employed alone or in unison to maintain intraocular pressure during surgery.

IOL (intraocular lens) injector (1) for introducing an IOL (100) into the eye, comprising: an injector body (2); a cavity (4) for holding the IOL (100) comprising a leading haptic (100b) and a trailing haptic (100c); a cartridge (5) ending at a distal end (5c) in an injection nozzle (5a); the injector body (2), the cavity (4) and the cartridge (5) having a channel (6) extending in axial direction (P); and an axially movable pushing plunger (7) being placed in the channel (6) of the injector body (2) for pushing the IOL (100) in axial direction (P) out of the cavity (4) and into the cartridge (5) and the injection nozzle (5a), wherein a folding plunger (8) is arranged in the channel (6) and is extending in axial direction (P), parallel to the pushing plunger (7); and wherein the cavity (4) comprises a trailing haptic rest (4c) for defining the direction of the trailing haptic (100c) of an IOL (100) arrange in the cavity (4), such that the folding plunger (8) when moved in axial direction (P) hits the trailing haptic (100c) of the IOL (100).

A method for treating hyperopia or presbyopia in a patient, the method comprising making a cut deep in the patient's cornea to create a two-dimensional slit adjacent to and generally parallel to an anterior surface of the cornea and injecting a liquid or semi-solid transparent filler material into the deep cut in an amount sufficient to flatten the posterior surface of the cornea to increase the refractive power of the cornea by a predetermined correction of up to about 5 diopters due to the physical flattening of the posterior surface of the cornea, wherein the transparent filler material comprises a refractive index of about 1.3 to about 1.6, and forms a corneal implant with a lenticular shape within the cornea.

A system comprising a hollow member is used to deliver a constrained corneal implant into a corneal pocket. The hollow member may be tapered and the system may further include an implant deformation chamber and an axial pusher to advance the implant through the hollow member.

Corneal implant applicator devices and methods of using. In some embodiments they include an implant applicator and an implant support, wherein the implant applicator and implant support are disposed relative to one another to form an implant nest that is adapted to house a corneal implant; wherein the applicator has a greater affinity for the corneal implant than the support.

An exemplary ocular implant insertion system includes a case and a preloaded ocular implant insertion apparatus. The apparatus includes first and second movable structures that move the ocular implant in a predetermined sequence. The respective configurations of the case and the ocular implant insertion apparatus are such that the ocular implant insertion apparatus is not removable from the case when the ocular implant insertion apparatus is in the pre-use state and is removable after the first movable structure has moved at least a portion of the optical implant.

A capsular tension ring inserter (10) and method includes a cannula (54) adapted to house a capsular tension ring (CTR) (26) having a leading eyelet (32), a hook element (56) disposed within the cannula (54) that engages and moves the CTR (26) during deployment, and a suture (28) placed on the leading eyelet (32) and fed back through the cannula (54) to allow a user to control insertion of the CTR (26) into a capsular bag (42) of an eye (40) by pulling on the suture (28) during insertion of the CTR (26).

Systems and methods for delivering multiple ocular implants to reduce intraocular pressure are disclosed. The ocular implants can be implanted at multiple sites within a single human eye without requiring removal of the delivery apparatus from the eye. A system for delivering multiple ocular implants can include at least two implants preloaded within a delivery device and configured to be implanted within the eye, a metering device configured to transfer energy to the implants for delivery at selected locations within the eye, wherein the metering device is configured to meter a variable amount of energy for each implant delivery event in the eye. The system can further include an injector mechanism configured to serially engage and drive each of the implants.

New multilayer ocular implant devices are provided. In certain aspects, the device is adapted for residence in the sub-Tenon's space of a patient's eye. In certain systems, separate layers of the implant device will contain distinct therapeutic agents, for example two or more different agents that can deliver desirable pharmacological effects, in certain preferred systems, the distinct therapeutic agents in separate device layers may provide a coordinated pharmacological effect, for example a first layer may contain a primary therapeutic agent and a second layer may contain a therapeutic agent that provides a supportive benefit to the primary therapeutic agent such as reducing side effects or enhancing patient uptake of the primary therapeutic agent or other delivery enhancement.

An external device is provided for use with an intraocular device configured to be implanted entirely in an eye of a subject. The external device includes a mount configured to be placed in front of the eye and a sensor coupled to the mount and configured to sense a level of ambient light. The external device additionally includes an external power source coupled to the mount and configured to (i) emit toward the eye non-visible light that is outside of 380-750 nm, and (ii) modulate the non-visible light based on the level of ambient light sensed by the sensor. Other application are also described.