Devices and methods for handling and depositing corneal implants onto corneal tissue. Devices and methods for packaging and storing corneal implants.

Corneal implant retaining devices and their methods of use. The retaining devices can be a cap adapted to be disposed over a portion of a corneal implant insertion device.

A method of implanting the prosthesis is disclosed. The method includes forming an opening in a host tissue of an eye. The method also includes forming a perimeter of a corneal graft. The method also includes forming a first passageway through the host tissue and a second passageway through the corneal graft. The first passageway and the second passageway can have the same diameter relative to an optic axis of the eye. The method also includes aligning the first passageway and the second passageway whereby the first passageway and the second passageway are in communication with one another. The method also includes positioning a body in the first passageway and the second passageway.

A method of manufacture is presented. The method includes providing a medical device, a drug delivery module, and an assembly device. The medical device comprises a first coupling feature; the drug delivery module comprises a second coupling feature and a product well. The assembly device comprises a top body comprising an implant press, middle body defining a module recess, and a base body defining a device receiver. The medical device is placed in the device receiver and the drug delivery module in the module recess. The top body, the middle body, and the base body, are aligned. Then a force is applied to the top body, wherein the force is sufficient for the implant press to cause the first coupling feature and the second coupling feature to couple to each other.

Systems, devices, and methods for delivering an implant to the orbit. In some instances, the systems may include a delivery device having a tongue member and a handle. The delivery device may further include an ejector configured to deliver an implant from the tongue member. The delivery device may also include a piercing member configured to create an opening in tissue. The systems may further include a piercing member for creating an opening in tissue. In some instances, the piercing member may have a first blade member rotatably connected to a second blade member.

A scleral prosthesis includes an elongated body having a first free end and a second free end opposite the first free end. A maximum width of the body at each end is wider than a maximum width of the body between the ends. The body includes multiple first portions that form the first free end of the body and a part of the body between the ends. The first portions are separated lengthwise along a substantial portion of a total length of the body. The first portions of the body are biased so that they maintain separation from one another without external interference but are configured to be pushed towards each other. The body is configured to receive and retain, between the first portions of the body, an insert that is configured to maintain the separation of the first portions.

An exemplary ocular implant insertion system includes a case and a preloaded ocular implant insertion apparatus. The apparatus includes first and second movable structures that move the ocular implant in a predetermined sequence. The respective configurations of the case and the ocular implant insertion apparatus are such that the ocular implant insertion apparatus is not removable from the case when the ocular implant insertion apparatus is in the pre-use state and is removable after the first movable structure has moved at least a portion of the optical implant.

A tool for endothelial implantation comprising a base frame on a stem and a covering frame such that the base frame is insertable between a stroma and a Descemet's membrane and the covering frame is positionable over the base frame to lockingly engage the base frame trapping a section of Descemet's membrane between the base frame and the cover frame for surgical separation of the section by cutting therearound.

A scleral prosthesis includes an elongated body configured to be implanted into scleral tissue of an eye. The body includes (i) opposing first and second free ends and (ii) multiple first portions that form the first end of the body and part of a remainder of the body between the ends. The first portions are separated along at least about half of a total length of the body by empty space such that the first portions meet at a point between the ends and are not connected to each other between that point and the first end. The ends are wider than the remainder. The scleral prosthesis also includes an insert configured to be placed between the first portions and to substantially fill the empty space. The body includes a convex upper surface extending lengthwise between the ends. The insert includes a convex upper surface extending lengthwise along the insert.

An external device is provided for use with an intraocular device configured to be implanted entirely in an eye of a subject. The external device includes a mount configured to be placed in front of the eye and a sensor coupled to the mount and configured to sense a level of ambient light. The external device additionally includes an external power source coupled to the mount and configured to (i) emit toward the eye non-visible light that is outside of 380-750 nm, and (ii) modulate the non-visible light based on the level of ambient light sensed by the sensor. Other application are also described.