Devices that are adapted to insert corneal implants onto corneal tissue. Methods of using the devices include inserting the corneal implant into a pocket created in the cornea. Methods of use also include inserting the corneal implant onto corneal tissue after a flap has been created in the cornea. The devices can be adapted to deliver fluid to an implant holding space to at least assist in the deployment of the implant from the holding space and onto corneal tissue.

A tube-shaped implant insertion device may comprise: a needle having an internal space to accommodate a tube-shaped implant inserted into an eyeball; a handle connected to the needle to manipulate the position of the needle; and a guide pin disposed to support the implant accommodated in the needle, and having a hollow size smaller than the outer diameter of the implant. When using the tube-shaped implant insertion device, a tube-shaped implant is inserted into an eyeball by supporting same by means of a hollow guide pin and, after insertion, the needle is retracted by using a handle, and thus, there is an advantage in that an implant with an internally inserted wick can be easily inserted into the eyeball while not being separated from a suture.

An intraocular implant and system comprising: an intraocular device coupled to an attachment mechanism operable to transition between a first configuration and a second configuration to secure the intraocular device to the eye; and a delivery device operable to deliver the intraocular device to the eye and manipulate the attachment mechanism to transition between the first configuration and the second configuration.

Systems and methods for delivering multiple ocular implants to reduce intraocular pressure are disclosed. The ocular implants can be implanted at multiple sites within a single human eye without requiring removal of the delivery apparatus from the eye. A system for delivering multiple ocular implants can include at least two implants preloaded within a delivery device and configured to be implanted within the eye, a metering device configured to transfer energy to the implants for delivery at selected locations within the eye, wherein the metering device is configured to meter a variable amount of energy for each implant delivery event in the eye. The system can further include an injector mechanism configured to serially engage and drive each of the implants.

The invention provides surgical procedures for implanting a keratoprosthesis in an eye of a subject in need using a kit comprising keratoprosthesis comprising a central optical core, a peripheral skirt around said central optical core, comprising at least one biocompatible polymer; and a marking tool comprising a polymeric surface in the shape of said central optical core.

An ablatable corneal inlay for correction of refractive errors and/or presbyopia, and a method of correcting refractive errors and presbyopia in an eye of a patient using an ablatable corneal inlay is disclosed herein.

Systems and methods for preparation of an implant and for ab interno insertion of the implant into an eye of a patient including a tissue cartridge configured to receive and hold a patch of a material; a cutting device; and a delivery device. Related devices, systems, and methods are provided.

Systems and methods for delivering multiple ocular implants to reduce intraocular pressure are disclosed. The ocular implants can be implanted at multiple sites within a single human eye without requiring removal of the delivery apparatus from the eye. A system for delivering multiple ocular implants can include at least two implants preloaded within a delivery device and configured to be implanted within the eye, a metering device configured to transfer energy to the implants for delivery at selected locations within the eye, wherein the metering device is configured to meter a variable amount of energy for each implant delivery event in the eye. The system can further include an injector mechanism configured to serially engage and drive each of the implants.

A medical device for office-based/operating room bleb forming minimally invasive glaucoma surgeries. The medical device includes a proximal segment for grasping by a user, a distal segment that includes a piercing member coupled to and extending from the distal segment, wherein the piercing member is configured to contain and deliver an ocular implant into an eye tissue layer to obtain a channel, wherein the proximal segment and the distal segment being configured to couple to each other at a pivot point between an unlocked configuration and a locked configuration, and wherein in the unlocked configuration, the proximal segment and the distal segment are rotatable relative to each other about a rotation axis at the pivot point.

The invention provides keratoprosthesis devices and kits and surgical methods of their use.