Assemblies for storing, handling, transporting, viewing, evaluating, and/or shipping corneal tissue are provided. The assembly includes a corneal tissue carrier within a vial, the transport vial removably coupled to a stabilization base, wherein the ease of access to the graft carrier allows administering the corneal tissue sample to a patient in rapid succession so that more surgeries can be performed by a single surgeon in a single day.

Medical kits and methods for performing small incision DLEK include a corneal transplantation donor tissue graft formed into an implantable and compact rolled configuration using the flexible substrate.

An example method for cutting a plurality of lenticules from a donor cornea includes receiving a donor cornea, cutting a first layer of a first set of lenticules from the donor cornea, and cutting a second layer of a second set of lenticules from the donor cornea. The lenticules are cut according to a pattern that to maximizes the number of lenticules, thereby maximizing the number of implants from the single donor cornea.

An example implant handling device includes a body. The body includes a flattened end configured to receive a corneal implant and keep the corneal implant from rolling or folding. The flattened end has a width and a height, the width being greater than the height. The body includes a slit opening to the flattened end, the slit opening configured to allow the corneal implant to pass into the flattened end.

An ocular clip implant (22) used for securing an intraocular lens (IOL) (62) in an eye of a patient is provided which includes an IOL-engaging portion (26) disposed at a first end of the ocular clip implant (22). The IOL-engaging portion (26) is configured to grasp a portion of the IOL (62). An ocular-wall-engaging portion (28) is integrated with and disposed at a second end of the ocular clip implant (22). The ocular-wall-engaging portion (28) includes an anchor (29) transitionable from a first, straightened configuration to a second, non-straightened configuration to anchor the ocular clip implant (22) to a wall of the eye in order to secure the IOL (62) to the eye. Other embodiments are also described.

A handheld implantation device for implantation of a retinal tissue implant at an implantation site. The handheld implantation device includes a handheld implantation tool having a leading implantation tool end and a trailing implantation tool end, an implant holder for peripherally holding a retinal tissue implant including an uppermost viable retinal tissue and a lowermost basement membrane and a clinician-operated attachment arrangement for initial attaching the implant holder at the leading implantation tool end and subsequent selected detaching the implant holder therefrom at the implantation site for implantation of the implant holder together with the retinal tissue implant thereat.

A device for the preparation of a Descemet's membrane-endothelium graft includes a bowl with an inner bottom and a sidewall surrounding the bottom, particularly the bowl being configured to receive a fluid and a Descemet's membrane-endothelium graft or a donor cornea graft comprising a Descemet's membrane-endothelium graft floating in the fluid, a preparation area positioned in a first part of the inner bottom of the bowl, particularly for receiving and preparing the graft prior to transport, a transfer area positioned in a second part of the inner bottom between the preparation area and an outlet opening in the sidewall, particularly the opening being entirely positioned below the upper rim of the sidewall.

There is disclosed a surgical device comprising a handle (14) for releasable attachment to a cartridge (1) adapted to hold an endothelial corneal implant in a scrolled or double coiled configuration. The handle has a forward end for releasable attachment to the cartridge, a rearward end and a gripping portion (60) between said forward and rearward ends. The gripping portion is substantially planar so as to facilitate being gripped between finger and thumb. The handle incorporates a first flexible fluid conduit (61) for releasable fluid connection to the cartridge at the forward end of the handle. There is further disclosed a surgical device comprising a handle having a forward end and a rearward end and a gripping portion between said forward and rearward ends. The gripping portion is substantially planar so as to facilitate being gripped between finger and thumb. The surgical device also comprises a cartridge having a forward end, a rearward end and a hollow interior that is open at the forward and rearward ends, the rearward end for releasable attachment to the forward end of the handle, and the hollow interior of the cartridge adapted to hold an endothelial corneal implant in a scrolled or double coiled configuration. In addition, the surgical device comprises a first flexible fluid conduit incorporated in the handle, wherein the first flexible fluid conduit is configured for releasable fluid connection to the rearward end of the cartridge at the forward end of the handle.

A system includes a scleral prosthesis and an insert. The scleral prosthesis includes a first end configured to be pulled through a scleral tunnel in an eye and a second end. Each end is wider than a middle portion of the scleral prosthesis. Two portions form the first end of the scleral prosthesis, and the portions are separated along at least half of a length of the scleral prosthesis. The scleral prosthesis is formed from a single integrated piece of material. The second end is undivided. The insert is configured to be placeable between the two portions. The two portions may be separated from one another without external interference, and the two portions may be configured to be pushed towards each other in order to reduce a width of the first end and then separate after release.

Modifying corneal shape involves implantation of a segment of tissue in the corneal stroma, where the properties of the tissue segment and its anatomical placement provide a change in corneal topography. In particular, such methods and materials can be used for correction of defects in corneal shape, such as corneal ectasias.

Devices and systems adapted for at least one of storing a corneal device and positioning a corneal device onto target tissue.