A device for manipulating an implant includes a handle coupled to a guide extending from the handle to a distal end. The device includes an engagement mechanism disposed at the distal end of the guide and configured to engage an implant. The device includes a first actuator disposed on the handle and coupled to the engagement mechanism. The first actuator causes the engagement mechanism to engage the implant. The device includes an air chamber disposed in an interior chamber of the handle and configured to hold air. The device includes a lumen coupled to the air chamber and extending along the guide to the distal end. The lumen includes an air channel extending through the lumen. The device includes a second actuator disposed on the handle. The second actuator causes the air chamber to deliver the air, via the air channel, to the distal end.

Embodiments of this invention generally relate to systems and methods for optical treatment and more particularly to non-invasive refractive treatment method based on sub wavelength particle implantation. In an embodiment, a method for optical treatment identifies an optical aberration of an eye, determines a dopant delivery device configuration in response to the optical aberration of the eye, wherein the determined dopant delivery device is configured to impose a desired correction to the eye to mitigate the identified optical aberration of the eye by applying a doping pattern to the eye so as to locally change a refractive index of the eye.

A tissue holding assembly for endothelial implantation comprising an open frame having legs for engaging a stem, such that said frame is insertable between a stroma and a Descemet's membrane, said frame being coated with a biological adhesive for adhering to a perimeter of a section of the Descemet's membrane to adhere the section of the Descemet's membrane to the frame for surgical separation of said section by cutting therearound, wherein said frame further comprises a heating element around its inner perimeter.

The invention relates to a device for providing and inserting a transplant or implant into a human or animal body, more particularly for ophthalmological operations, preferably for performing a lamellar keratoplasty, such as a DMEK operation, comprising a cartridge (1) or sleeve, which has a holding region (2) for the transplant or implant and two opposite end openings (3, 4) each fluidically connected to the holding region (2), wherein the first opening (3) has a larger diameter than the second opening (4) and wherein, in order to produce a fluidic connection between the holding region (2) and a syringe (5), both openings (3, 4) can be coupled to the syringe (5) directly or by means of a connecting apparatus. With a view to simply and safely providing and inserting a transplant or implant into the body by simply designed means, the device is designed and further developed in such a way that the cartridge (1) or sleeve is mounted in a holder (6) and that the holder (6) has a pivoting apparatus (7) for pivoting the cartridge (1) or sleeve about a pivot axis (8) into a coupling position for coupling at least one of the two openings (3, 4) to the syringe (5). The invention further relates to a ready-to-use set comprising a device as described above in a sterile packaging.

The invention relates to an apparatus for changing the refractive power of the cornea (1), in particular for correcting hyperopia or presbyopia, exhibiting injection means (13, 15) having at least one hollow needle (15) for injecting at least one optically transparent filling material having a predetermined refractive index into an intrastromal corneal pocket (7), characterized by a controllable injection drive (17) that is coupled at least indirectly to the injection means (13, 15) and is designed for changing an amount, to be injected, of the at least one filling material; a device for optical coherence tomography (OCT) (19) that is designed for monitoring the area of the corneal pocket (7) by means of measurement of depth profiles of the cornea (1) on a repeatedly cycled-through scan pattern; and a computing unit (21) that is designed and/or configured to determine from the measurement data of the OCT device (19) at least the radius of curvature of the front (3) of the cornea (1) keeping pace temporally with the repetitions of the scan pattern cycle during the injection, wherein the computing unit (21) is designed and/or configured to control the injection drive (17) for changing the injected amount of the at least one filling material, and namely on the basis of the radius of curvature of the front (3) of the cornea (1) and/or such until a predetermined target criterion is fulfilled.

An injector of intracorneal segments has a disposable segment holding head comprising a lancet (36) formed with a housing closed by the lid (37) wherein a sterilized corneal segment (11) is housed, behind which there is a needle (26) longitudinally slidable under the action of a trigger (31) and a spring (32). The head also has a manual selector (38) to deflect the needle to place the segment at 90° of the head to the right or left of a channel made in the cornea for injection. The segment pre-installed in the head is provided with recesses formed by knurling (16) on its outer chord (14) where it couples to the needle for the push.

Medical kits and methods for performing small incision DLEK include a corneal transplantation donor tissue graft formed into an implantable and compact rolled configuration using the flexible substrate.

Embodiments of this invention generally relate to systems and methods for optical treatment and more particularly to non-invasive refractive treatment method based on sub wavelength particle implantation. In an embodiment, a method for optical treatment identifies an optical aberration of an eye, determines a dopant delivery device configuration in response to the optical aberration of the eye, wherein the determined dopant delivery device is configured to impose a desired correction to the eye to mitigate the identified optical aberration of the eye by applying a doping pattern to the eye so as to locally change a refractive index of the eye.

A delivery system for an ocular implant includes a delivery tube having a delivery end with an opening and a control end. A delivery device fits at least partially within the delivery tube. The delivery device is configured to contact the ocular implant and control the position of the ocular implant within the delivery tube. The delivery system includes a fluid inlet nozzle that injects fluid into the delivery tube between the control end and the ocular implant. The injected fluid flows around the sides of the ocular implant and out from the delivery end of the delivery tube.

An injector for ejecting an intraocular lens for injecting the latter into an eye or for implanting a corneal endothelial tissue, comprising an elongate injector body which has a piston rod passage and in which an injector piston rod having a screw thread is guided in a longitudinally displaceable manner. The injector is provided with two operating modes for the displacement of the injector piston rod and is able to be switched between the modes. The first operating mode defines an ejection operation and the second operating mode defines a screwing operation. The injector body has at least one retractable and deployable wing grip, wherein the operating mode is set to ejection operation by the deployed position and the operating mode is set to screwing operation by the retracted position. The injector piston rod comprises a stop element.