This disclosure describes a Descemet's membrane endothelial keratoplasty (DMEK) graft prepared using paired incisions; compositions including the incised DMEK graft; an injector including the incised DMEK graft; a viewing chamber including the incised DMEK graft, methods of preparing the incised DMEK graft; and methods of using the DMEK graft, the compositions, the injectors, and the viewing chambers including to facilitate placement of DMEK grafts during cornea transplant surgery.

Assemblies for storing, handling, transporting, viewing, evaluating, and/or shipping corneal tissue are provided. The completed fitted assembly supports and allows for transporting a graft or implant with an assembly that comprises; a vial that is either cylindrical or rectangular cuboid and lid that includes a poly-cone insert, a support base so that the vial is able to stand upright and remain motionless, support columns integrated seamlessly within the vial with apertures that provide for full fluid communication and notches for positioning and support of an assembled corneal tissue carrier that is suited to accommodate compressive force generated between said lid and said notches, in addition to being able to accommodate a tissue carrier assembly via compression forces between said lid and a bottom surface of said vial, and a rectangular cuboid shape that also includes a flat transparent surface that provides inspection of corneal tissue visually or via instrumentation.

Assemblies for storing, handling, transporting, viewing, evaluating, and/or shipping corneal tissue are provided. The assembly includes a corneal tissue carrier within a vial, the transport vial removably coupled to a stabilization base, wherein the ease of access to the graft carrier allows administering the corneal tissue sample to a patient in rapid succession so that more surgeries can be performed by a single surgeon in a single day.

A handheld implantation device for implantation of a retinal tissue implant at an implantation site. The handheld implantation device includes a handheld implantation tool having a leading implantation tool end and a trailing implantation tool end, an implant holder for peripherally holding a retinal tissue implant including an uppermost viable retinal tissue and a lowermost basement membrane and a clinician-operated attachment arrangement for initial attaching the implant holder at the leading implantation tool end and subsequent selected detaching the implant holder therefrom at the implantation site for implantation of the implant holder together with the retinal tissue implant thereat.

A capsular tension ring inserter (10) and method includes a cannula (54) adapted to house a capsular tension ring (CTR) (26) having a leading eyelet (32), a hook element (56) disposed within the cannula (54) that engages and moves the CTR (26) during deployment, and a suture (28) placed on the leading eyelet (32) and fed back through the cannula (54) to allow a user to control insertion of tile CTR (26) into a capsular bag (42) of an eye (40) by pulling on the suture (28) during insertion of the CTR (26).

A device and method for aspirating graft tissue and delivering the graft tissue to a target delivery site (for example, when performing Descemet's membrane endothelial keratoplasty). In one embodiment, an injector comprises a cylinder and a plunger at least partially located within the cylinder, the plunger being rotatably advanceable and retractable within the cylinder. In one aspect of the embodiment, rotating the plunger in a first direction within the cylinder controllably aspirates a graft tissue into the injector and rotating the plunger in a second direction opposite the first direction controllably ejects the graft tissue from the injector.

An eye enlargement implant and a method of performing a cosmetic procedure for the beauty of eyes, which is capable of being inserted into the eyes so as to make the eye look crisper and bigger, and being removed when it is not necessary without causing eye inflammation and without having to be replaced, the implant including a ring-shaped body which is inserted between a sclera and a conjunctiva of an eyeball having an inner diameter portion having at least a size enough to surround an outer periphery of the cornea, and an outer diameter portion having a width size of 0.8 to 1.2 mm so as to cover a white portion and having a maximum thickness of 0.05 to 0.20 mm at the center portion, where the ring-shaped body has flexibility and a predetermined color which is similar to that of the iris.

An example method for cutting a plurality of lenticules from a donor cornea includes receiving a donor cornea, cutting a first layer of a first set of lenticules from the donor cornea, and cutting a second layer of a second set of lenticules from the donor cornea. The lenticules are cut according to a pattern that to maximizes the number of lenticules, thereby maximizing the number of implants from the single donor cornea. An example implant handling device includes a body. The body includes a flattened end configured to receive a corneal implant and keep the corneal implant from rolling or folding. The flattened end has a width and a height, the width being greater than the height. The body includes a slit opening to the flattened end, the slit opening configured to allow the corneal implant to pass into the flattened end.

A method for treating hyperopia or presbyopia in a patient, the method comprising making a cut deep in the patient's cornea to create a two-dimensional slit adjacent to and generally parallel to an anterior surface of the cornea and injecting a liquid or semi-solid transparent filler material into the deep cut in an amount sufficient to flatten the posterior surface of the cornea to increase the refractive power of the cornea by a predetermined correction of up to about 5 diopters due to the physical flattening of the posterior surface of the cornea, wherein the transparent filler material comprises a refractive index of about 1.3 to about 1.6, and forms a corneal implant with a lenticular shape within the cornea.

An apparatus (200, 200A, 200B, 200C) has central lens body (212, 212A, 212B, 212C) for providing vision correction for a patient. The lens body (212, 212A, 212B, 212C) has an initial index of refraction and is formed from at least one material configured to have a second index of refraction when subjected to a laser and/or radiation.