Methods for producing a custom-made stapes prosthesis for a patient and stapes prostheses so produced. The methods may include obtaining a three-dimensional image of a natural stapes bone of the patient; and forming a stapes prosthesis that closely approximates a three-dimensional shape of the natural stapes bone via an additive manufacturing technique based on the three-dimensional image. The stapes prosthesis comprises a suitable material that is not osteogenic and is not cytotoxic. The stapes prosthesis may include a plurality of pores having an average size of from about 5 to about 100 micrometers and may exhibit a frequency of sound transmission in a range of from about 2 to about 30 kilohertz.

Certain embodiments described herein provide a method of performing an otological surgical procedure including surgically accessing a middle ear, injecting a perfluorocarbon liquid into the middle ear, and suctioning the isolated blood from the middle ear without removing the perfluorocarbon liquid. The perfluorocarbon liquid is immiscible with blood for isolating blood in the middle ear from the perfluorocarbon liquid. In certain embodiments, the perfluorocarbon liquid has a specific gravity greater than blood to apply positive pressure to surrounding tissues. In certain embodiments, the method includes suctioning the perfluorocarbon liquid from the middle ear after the isolated blood is removed.

The disclosure relates to winged graft devices, methods of manufacture, and methods of use to repair, e.g., repair perforations, in tympanic membranes, or to augment defective tympanic membranes.

Provided is a polymeric auricular scaffold for use in auricular implants and methods for making them. The disclosed polymeric auricular scaffold is formed using a biocompatible polymer sheet that is vacuumed formed into a shape representing auricular cartilage using a vacuum forming mold.

Machine-learning techniques are used to train a classifier to predict auditory and language skills improvement in a patient who is a candidate for cochlear implantation (CI). One or more images of portions of the patient's brain are obtained, and quantitative data is extracted that represents the composition of one or more brain areas related to auditory and/or cognitive processing. For training of the classifier, data is obtained for previous CI patients whose improvement in language skills has been measured. Once trained, the classifier can be used to predict a likely degree of improvement in a prospective CI patient's auditory and language skills.

A medical implant includes a sensor that detects electromagnetic waves; and a data transmission unit that can wirelessly transmit data supplied by the sensor to a receiving unit.

A length-adjustable ossicular prosthesis, includes a cylindrical pin serving as a connecting element, which connects a foot element to a head element. The head element is intended to be disposed on an inside of an eardrum, and the foot element is intended to be attached to an anvil in a human ear. The head element is designed as an elliptical ring having an opening, which can be closed by closing a locking mechanism comprising a hook. Two guiding and clamping elements project inwardly from the ring, between which, in an open position, the connecting element is displaceably guided, and which secure the head element non-displaceably and non-rotatably on the connecting element when the ring is closed, and as a result the guiding and clamping elements are tensioned against the connecting element.

Systems and methods can be employed for trans-tympanic membrane access to the middle ear for delivery of a therapeutic agent, for example, to the round window niche adjacent to the cochlea under direct visualization. The systems and methods can also be used to improve accessibility and visualization for various otological surgical procedures, such as, but not limited to, cholesteatoma removal, tympanic membrane repair and ossicular chain repair.

The present invention relates to a device for repair of a region within an ear via a natural orifice, the device comprising a body. The body comprises a first port for visibly identifying the region to be sealed, the region being inside the ear; and a second port through which a seal can be introduced into the ear through the device. The region comprises a perforation of a tympanic membrane of the ear and the device is a speculum. The present invention also relates to method for repairing a perforation in a tympanic membrane using the same device.

A hearing prosthesis, comprising: a microphone; a sound processor; an external transmitter unit including a coil; an internal receiver unit including a coil; a stimulator unit, wherein the stimulator unit includes a control circuit, a voltage measurement component, a resistor and a signal generator, wherein the measurement circuit is configured to output a signal indicative of the voltage across the resistor; and a stimulating lead assembly array, wherein at least a portion of the hearing prosthesis is configured to apply an electrical signal to tissue inside a cochlea of a recipient, and at least a portion of the hearing prosthesis is configured to sense an electrical property inside of the cochlea that results from the applied electrical signal and the interaction of the applied electrical signal to the tissue.