An accurate and precise surgical guide for dental procedures, especially a procedure involving a subject with few or no teeth as well as methods for making and use of such guides.

Described herein are methods and devices for delivering a drug to the frontal sinus system. An inflatable implant is positioned within the frontal sinus system using an anchoring means secured within the frontal sinus cavity. A drug-containing fluid is released directly into the frontal sinus drainage system.

This disclosure describes, inter alia, materials, devices, kits and methods that may be used to treat chronic sinusitis, including method for assessing sinonasal protein and mRNA markers as an indicator of a positive therapeutic response to treatment.

Nasal implants are provided that have a planar type profile with open spaces through portions of the planar type profile. The nasal implant can be compressible along one or more dimensions of the nasal implant, such as the width and length of the planar type profile. Delivery tools for deploying the nasal implants within the nasal tissue are also provided. Methods for deploying the nasal implants within the nasal tissue of the patient are also provided.

A stent (100) that is sleeved and radially expandable, and which in an expanded state provides a breathable, generally tubular structure sized and shaped for residence in a sinus or nasal cavity or passage, and in an unexpanded state has a cross-sectional diameter suitable for insertion into such cavity or passage. The sleeve limits expansion and outward pressure exerted by the stent and thereby can prevent or reduce the incidence of headache in patients, and can provide increased surface area for improved elution of drugs to nearby mucosal tissue.

Systems and methods are provided for altering the shape of a target tissue structure of a subject, e.g., a nasal septum or other nasal tissue that include securing a first end of a shaping element to tissue adjacent the structure; manipulating the tissue to alter a shape of the structure; and applying a force to the shaping element to maintain the altered shape of the structure.

A system and method for maintaining a patent paranasal sinus ostium includes delivering a tubular element in an insertion state to the sinus ostium. The tubular element includes a proximal end, a distal end, and a center region between the proximal end and the distal end. The method includes expanding the tubular element from the insertion state to a deployment state when the tubular element is located in the sinus ostium. In the deployment state, the center region confronts the sinus ostium with an outward radial force. Other embodiments are disclosed.

Described here are systems, devices, and methods for delivery of an implant to a bodily cavity. The implant may include a hub and a plurality of legs, and may be moveable between a low-profile and expanded configuration. The systems may include a crimping device having a crimping member with a plurality of arms. The plurality of arms may engage the plurality of legs of the implant, and may move the legs to move the implant to the low-profile configuration. In some instances a delivery device may aid in crimping and/or delivery of the implant.

A method for providing a surgical implant, based on a system for a first terminal for initially designing a surgical plan by a patient, a second terminal for finalizing a surgical plan by a surgeon, and a server for communicating with the first terminal and the second terminal and further designing an implant according to the surgical plan, including, obtaining, by the server, a first 3D image based on a patient medical image data including at least one of a surgical part; transmitting, by the server, the first 3D image to the first terminal to obtain at least one modified second 3D image corresponding to a surgical plan initially designed by the patient, from the first terminal; transmitting, by the server, the at least one modified second 3D image to the second terminal to obtain a final third 3D image corresponding to a surgical plan designed by the surgeon, from said second terminal; and designing, by said server, an implant based on the patient medical image data, the first 3D image, the second 3D image, and/or the third 3D image.

This disclosure describes, inter alia, materials, devices, kits and methods that may be used to treat chronic sinusitis. More specifically, a drug-eluting scaffold is implanted in the middle meatus to treat chronic sinusitis for weeks to months.