Systems and methods for native heart valve repair includes an anchor. The anchor includes an anchor body configured to transition from a first configuration, in which the anchor body is straightened for transvascular delivery to the native heart valve, to a second configuration comprising at least two turns for implanting at the native heart valve. Two or more of the at least two turns in the second configuration have a diameter smaller than a major axis of the native heart valve.

An implantable heart valve configured for implantation within an existing prosthetic heart valve includes a frame including struts defining a lattice region and a plurality of arches, and a central lumen extending therebetween, a plurality of protrusions extending radially outward from the plurality of struts, and a valve coupled to the frame and positioned within the central lumen.

The present embodiments provide a medical device for implantation in a patient comprising a stent and a valve. The stent comprises a proximal region comprising a cylindrical shape having a first outer diameter in an expanded state, and a distal region comprising a cylindrical shape having a second outer diameter in the expanded state. The second outer diameter is greater than the first outer diameter. A proximal region of the valve is at least partially positioned within the proximal region of the stent, and the distal region of the valve is at least partially positioned within one of tapered and distal regions of the stent. When implanted, the proximal region of the stent and the proximal region of the valve are aligned with a native valve, and the distal region of the valve is distally spaced-apart from the native valve.

An artificial heart valve includes support structure having a first end and second end and defining an interior of the valve. A covering covers the support structure and includes an intermediate portion with a plurality of intermediate strip-shaped sections having cuts between them. Some are attached to the stent and others are not so that a closed configuration prevents retrograde blood flow into an interior of the stent with the free strip-shaped sections abutting the stent and overlapping or abutting the attached strip-shaped sections to prevent retrograde blood flow into the interior. An open configuration is formed with the unattached strip-shaped sections lifting from the stent to allow antegrade blood flow from the interior of the stent.

A knotless suture fastener installation system for securing medical devices such as cardiac implants. The knotless suture fasteners may be spring-biased so as to grip onto sutures passed therethrough. The system includes a fastener deployment tool with a proximal handle and a distal shaft to which a fastener cartridge attaches. A plurality of disposable cartridges are sequentially attached to the end of the deployment tool and used to secure the medical implant one fastener at a time. The deployment tool may also cut the sutures being fastened.

An endoluminal prosthesis includes a stent-graft and a temporary aortic valve, typically combined in an integrated assembly suitable for transfemoral or other endoluminal placement in a patient's ascending aorta, aortic root, and aortic valve. The stent-graft has a base end configured to be positioned into over the patient's aortic root and over the aortic annulus. The temporary aortic valve assembly is attached to the base end of the stent-graft and comprises a scaffold configured to be anchored in the patient's aortic annulus and valve leaflets configured to function temporarily after the endoluminal prosthesis has been implanted. At least one fenestration suitable for receiving a guidewire and/or a coronary stent graft is located near a junction between the base end of the stent graft and the temporary aortic valve, wherein said at least one fenestration is disposed on the endoluminal prosthesis to be aligned with one of the patient's coronary ostia after the endoluminal prosthesis has been implanted.

Medical delivery system for accessing a tricuspid valve via an inferior vena cava, including an outer guide catheter, an inner guide catheter and an interventional catheter. The first deflection portion of the outer guide catheter is steerable to define a first outer-guide-catheter curve and the second deflection portion of the outer guide catheter is steerable to define a second outer-guide-catheter curve and the first deflection portion of the inner guide catheter is steerable to define a first inner-guide-catheter curve.

Methods and devices that prevent stasis in the LAA by either increasing the flow through the LAA or by closing off or sealing the LAA. Increasing the flow is accomplished through shunts, flow diverters, agitators, or by increasing the size of the ostium. Closing off the LAA is accomplished using seals or by cinching the LAA.

Prosthetic valves and associated methods and systems are disclosed, including a prosthetic valve with a support structure and a leaflet construct coupled to the support structure, and a tissue cutting element coupled to a portion of the prosthetic valve.

A quick-connect heart valve prosthesis that can be quickly and easily implanted during a surgical procedure is provided. The heart valve includes a substantially non-expandable, non-compressible prosthetic valve and a plastically-expandable frame, thereby enabling attachment to the annulus without sutures. A small number of guide sutures may be provided for aortic valve orientation. The prosthetic valve may be a commercially available valve with a sewing ring with the frame attached thereto. The frame may expand from a conical deployment shape to a conical expanded shape, and may include web-like struts connected between axially-extending posts. A system and method for deployment includes an integrated handle shaft and balloon catheter. A valve holder is stored with the heart valve and the handle shaft easily attaches thereto to improve valve preparation steps.