A valve (2) comprising: (a) membrane (50) and (b) a frame (10) in communication with the membrane so that the frame expands the membrane, the frame including: (i) a rod (4), (ii) a plurality of struts (12) connected to the rod at a distal end and extending generally radially outward as the struts extend away from the distal end and towards a proximal end; (iii) a plurality of anchors (30) that are in direct communication with the struts between the distal end and the proximal end, each of the plurality of anchors extending through an exit location (52) in the membrane.

It is proposed to provide and implantable tube valve for implanting in a urinary tract, comprising: an implantable tube; a valve member mounted inside the tube and pivotable between an open position and a closed position and an actuator for pivoting the valve member; wherein the valve member comprises a pivot part, said pivot part formed as a single beak part; said valve member provided with a safety mechanism including a biasing element, an actuator, and the pivot part, wherein the beak part is arranged to pivot the pivot part towards the open position when a pressure exerted on the beak part exceeds a predetermined pressure.

A system includes a stent positionable within a coronary vein. The stent includes a valve and a stent body coupled to the valve and arranged to transition between a collapsed state and an expanded state. The system includes an intravascular reperfusion therapy device with a sensor and a catheter with a lumen shaped to receive the stent. The intravascular reperfusion therapy device delivers reperfusion therapy to a myocardium of a heart. The system includes a processor circuit that receives physiological data from the sensor, determines a progression of the reperfusion therapy, controls a configuration of the valve and/or the expansion state of the stent such that back pressure is controlled. With the stent in the expanded state, the stent body contacts a wall of the coronary vein and the valve obstructs blood flow in a first direction to generate the back pressure in an opposite, second direction.

The present invention provides a modular prosthetic valve device having two or more device modules for percutaneous delivery unassembled at or near the valve implantation site and assembly at least in part using a self-assembly member, and a system and method of folding, delivering and assembling the device. The device modules may include a support structure and a valve module. The valve module has an unassembled, folded delivery configuration, and an unfolded, assembled (via the self-assembly member) working configuration. The valve module may be a single-piece leaflets substructure or a plurality of valve sections. The self-assembly member has a delivery configuration and may be reverted to a preset configuration for valve module assembly. The unassembled valve module may be rolled along its circumferential axis towards its height to a folded diameter equivalent to one rolled leaflet, providing a percutaneous valve device having a smaller delivery diameter than pre-assembled valve devices.

Devices are provided with an internal dimension that can be reduced and increased in vivo. In one example, an interatrial shunt for placement at an atrial septum of a patient's heart includes a body. The body includes first and second regions coupled in fluid communication by a neck region. The body includes a shape-memory material. The body defines a passageway through the neck region for blood to flow between a first atrium and a second atrium. The first and second regions are superelastic at body temperature, and the neck region is malleable at body temperature. A flow area of the passageway through the neck region may be adjusted in vivo.

According to certain aspects, an implant device comprises an outer member configured to position the implant device within one or more pulmonary vessels. The implant device also comprises an inner member comprising one or more blades configured to modify one or more of forward waves or backward waves within the one or more pulmonary vessels to reduce interference between the forward waves and the backward waves during systole, the one or more blades having a shape or surface that directs a portion of the forward waves to a region of the one or more pulmonary vessels.

Implantable artificial bronchi for the treatment of chronic obstructive pulmonary diseases, such as pulmonary emphysema. The implantable artificial bronchus can be made with silicone or nitinol. The embodiments of this invention may be further associated with a one-way valve.

A stent graft has a tubular body with a first bifurcation with first and second legs extending from the bifurcation. One of the legs has a further bifurcation to define a side arm. The stent graft can be deployed into the vasculature of a patient with the tubular body being in an aorta of the patient, a first leg extending down an iliac artery, a second leg being directed towards a contralateral iliac artery and the side arm directed to an internal artery of one of the iliac arteries. One of the legs can include a valved aperture to enable the placement of an indwelling catheter therethrough.

A differential pressure regulating device is provided for controlling in-vivo pressure in body, and in particularly in a heart. The device may include a shunt being positioned between two or more lumens in a body, to enable fluids to flow between the lumens, and an adjustable flow regulation mechanism being configured to selectively cover an opening of the shunt, to regulate the flow of fluid through the shunt in relation to a pressure difference between the body lumens. In some embodiments a control mechanism coupled to the adjustable flow regulation mechanism may be provided, to remotely activate the adjustable flow regulation mechanism.

An iron based and absorbable implanted prefabricated tube (1) for medical device and preparation method therefor, and a medical device prepared by the prefabricated tube and preparation method therefor. The average nitrogen content of nitrogen in the prefabricated tube is from 0.04-0.4 wt. % or 0.02-0.04 wt. %. The prefabricated tube can be cut along the length direction directly by laser or by machining to obtain multiple absorbable implanted medical devices.