Provided herein are scaffold biomaterials including a decellularized plant or fungal tissue from which cellular materials and nucleic acids of the tissue are removed, the decellularized plant or fungal tissue having a 3-dimensional porous structure; wherein the decellularized plant or fungal tissue may optionally be at least partially coated or mineralized, wherein the scaffold biomaterial may optionally further include a protein-based hydrogel and/or a polysaccharide-based hydrogel, or both. Also provided herein are methods and uses of such scaffold biomaterials, including methods of manufacture as well as methods and uses for bone tissue engineering, for example.

An auxiliary tool for surgery includes an auxiliary tool main body part, and a first leg pair located on the auxiliary tool main body part. A tail end of the first leg pair is connected to the auxiliary tool main body part, a first mounting part is formed at a front end of the first leg pair, and the first mounting part is configured to clamp and press a surgical device to place the surgical device in a predetermined position.

An anchoring fixture for anchoring a prothesis to a skull bone may comprise a screw thread apparatus including a screw thread having a varying outer diameter and formed along a longitudinal length of the anchoring fixture; a flange configured to function as a stop for the anchoring fixture adapted to rest on top of the bone when the anchoring fixture is implanted into the bone; at least a main relief chamber formed into a portion of the screw thread having a first side along the longitudinal length that is curved shaped, and wherein the anchoring fixture is tapered over at least a first portion of the longitudinal length of the anchoring fixture and where the first portion is arranged at a distal end of the anchoring fixture, and where the distal end is opposite to the flange.

A universal low-profile intercranial assembly includes a mounting plate and a low profile intercranial device composed of a static cranial implant and an interdigitating functional neurosurgical implant. The low profile intercranial device is shaped and dimensioned for mounted to the mounting plate.

An orbital implant adapted for attachment to the very thin bone at the orbit rim (502), such as the zygomatic and frontal bone margin at the supero-lateral aspect (501) of the orbit (503), for the attachment of an eye prosthesis directly to distal ends of inwardly convergently orientated transdermal abutments. The orbital implant has a baseplate (100) having an orbit radius curvature and an orbit rim curvature and a plurality of microfixation apertures therethrough and the plurality of transdermal abutments are located at an inner edge of the baseplate (100).

The invention relates to an implant (1) for the treatment of bone, in particular for covering defects or drill holes or for the reconstruction of bone defects or malformations. This comprises at least one frame structure (2) and at least one adaptation area (3). The edge of the implant (4) is thereby partially, but not continuously, formed by the frame structures (2), which are located outside the adaptation area (3).

Craniofacial implants for neuroplastic surgery structured for filling cranial bone voids in the skull designed, shaped and manufactured to address problems including cranioplasty failure, soft tissue thinning above the implant, overlying scalp atrophy leading to contour irregularities and/or scalp breakdown with exposure/infection, ineffective pre-fabricated shapes with sharp corners requiring manually bending or cutting the implants for proper form/shape, and additional operative time and anesthesia morbidity, and a need to spend time hand-trimming prong edges along the perimeter to ensure an absence of sharp edges and/or corners capable of injuring the scalp/soft tissue above, leading to chronic pain. The craniofacial implants for neuroplastic surgery are configured to have an improved shape absent corners, a smoother contour, a shape addressing co-existing soft tissue temporal deformity/atrophy, and/or a smoother, frictionless coating in order to prevent complications leading to suboptimal outcomes and implant removal by way of prior art implants.

The present invention is directed to methods for collecting and processing autografts, processed autografts, kits for collecting and transporting autografts, and tools for preparing autografts. It is also directed to autologous bone grafts, and methods of preparing them.

A personalized medical device intended for correction of defects, in particular in the orofacial area is multicomposite and comprises a hard tissue replacement and a soft tissue replacement. The hard tissue replacement is a hard core of biocompatible thermoplastic material and the soft tissue replacement is a biocompatible elastic substance. Preparation of personalized medical device even in the prenatal period using CT, MRI and 3D/4D electronic USG imaging and “additive manufacturing” technology.

Disclosed is a medical device comprising a porous structure, wherein a configuration of the porous structure varies in dependence on a load applied to the porous structure, such that the porous structure has a first configuration when the load is of a first magnitude, and has a second configuration when the load is of a second magnitude greater than the first magnitude. The porous structure comprises a first surface portion and a second surface portion. The first surface portion is disengaged from the second surface portion when the porous structure has the first configuration, and is engaged with the second surface portion when the porous structure has the second configuration.