A method for configuring a surgical guide and an associated implant. The implant and surgical guide are for maxillofacial osteosynthesis. Three-dimensional models of the pre- and post-operative anatomy are used to define attachment points. These attachment points are used to determine a structure for the implant and surgical guide.

Provided herein is an implant made of a biocompatible ceramic of synthetic origin obtained by additive manufacturing. The implant may include a dense portion featuring a material density by volume greater than 70%, and a porous portion connected to the dense portion by a connection zone. The porous portion may have an average macroporosity having a material density ranging from 30% to 70% by volume and cavities defining cavity sections, with a diameter ranging from 0.3 mm to 1.2 mm. The dense portion and the porous portion may define an external surface. The cavities may open onto the external surface.

A medical product for use during the treatment of a bone defect, having a plurality of individual elements that are connected to one another such that individual elements adjacent to one another engage in one another/are chained to one another. The individual elements of the chain net are subdivided into main elements and connection elements that are designed differently from the main elements. The main elements and the connection elements form, when chained to one another, a grid structure that is flat in the x-y plane.

A human implant includes at least one osteoconductive scaffold and at least one main carrier. The at least one osteoconductive scaffold is made of a metal material, is manufactured by 3D printing, and has at least one connecting portion, at least one separation element, and a proliferation portion. The at least one connecting portion is porous. The at least one separation element is disposed on one of two sides of the at least one connecting portion. The proliferation portion is disposed on one of two sides of the at least one separation element away from the at least one connecting portion, wherein osteoblasts proliferate in the proliferation portion. The at least one main carrier is made of a medical macromolecular material and is mounted to the at least one connecting portion being porous, such that the at least one main carrier is mounted to the at least one osteoconductive scaffold.

Methods and apparatus for designing a skull prosthesis are disclosed. In one arrangement, imaging data from a medical imaging process is received. The imaging data represents the shape of at least a portion of a skull. The imaging data is used to display on a display device a first virtual representation of at least a portion of the skull. User input defining a cutting line in the first virtual representation is received. A surgical operation of cutting through the skull along at least a portion of the defined cutting line to at least partially disconnect a target portion of the skull from the rest of skull is simulated. Output data is provided based on the simulation. The output data represents a simulated shape of at least a portion of the skull with the target portion at least partially disconnected from the rest of the skull, thereby defining the shape of an implantation site for a skull prosthesis to be manufactured.

The present disclosure provides a burr hole cover (e.g., burr hole cover) and method of manufacturing such apparatus. The burr hole cover disclosed herein may be multi-functional in that it may be used to: (a) form a burr hole which provides access to the brain, and (b) facilitate concealing the burr hole without employing any fastening devices (e.g., surgical screws, wires, etc.). In embodiments, the burr hole cover may include a sleeve having an outer surface, an inner surface, and a hollowed portion. In embodiments, the outer surface of the sleeve may define external serrations. The sleeve may be configured to create a burr hole in a skull, and the external serrations may be configured to secure the sleeve within the burr hole. The burr hole cover may also include a plate configured to fit with the sleeve and conceal the burr hole.

Systems and methods are provided for altering the shape of a target tissue structure of a subject, e.g., a nasal septum or other nasal tissue that include securing a first end of a shaping element to tissue adjacent the structure; manipulating the tissue to alter a shape of the structure; and applying a force to the shaping element to maintain the altered shape of the structure.

An implant for at least partially filling a bore hole in a bone includes a biocompatible plate and a support structure. The support structure has a ring-shaped inner support frame having an outer surface defining the outer diameter of the inner support frame and an inner surface, and an outer support frame having a plurality of fastening points adapted for attaching the implant to bone surrounding a bore hole in which the plate is inserted. The outer support frame is connected to and extends away from the outer surface of the inner support frame. A method of forming the implant is also provided.

The present invention relates generally to biocompatible medical devices, such as cranial implants, and a method and means of attaching to bone. More specifically, the present invention relates to multilayered porous material with controlled porosity and drug load designed to control the release of drugs from a medical device. Additionally the present invention provides methods for controlling release of drugs by integrating the multilayer structure in medical devices with successive layers of polymer coatings of different porosities and drug contents. The multilayer material is inserted in between two plates such as meshes that provide strength to the implant. The present invention relates to biocompatible medical devices that has osseointegration and antibacterial properties. The present invention also relates to a method and means of attaching the medical device to defect in a bone structure and comprises of tree mounting parts configured to secure the medical in place.

A customized head protection device comprising: a base plate shaped and dimensioned to shield a cranial defect area of a subject, the base plate comprising an cranial defect outline defining a first parameter around the cranial defect area, and a margin outline defining a second parameter around the first parameter, wherein the area between the first parameter and the second parameter defines an extension region adapted to fit onto a skin portion of the subject when worn. Also provided is a method of manufacturing the head protection device comprising identifying the cranial defect area of the subject, determining the aforementioned cranial defect and margin outlines, generating a 3D model object and 3D printing the device based on the 3D model object.