A system and method for improving upon an ability of a surgeon to repair traumatic bone injury using new materials, components, and structures. A structure may be used as an implant or a component of an external fixator for a fractured long bone with that structure having anisotropic and viscoelastic properties, such as through additive manufacturing techniques.

A particle comprising hydroxyapatite, β-tricalcium phosphate, α-tricalcium phosphate, and/or bioactive glass is provided. The particle can be useful in bone graft compositions further comprising a carrier. The composition can include a quadphasic particle having hydroxyapatite, β-tricalcium phosphate, α-tricalcium phosphate, bioactive glass, and a carrier. The particle can have a size in the range of 50 microns to 2.5 mm. A method of repairing a bone defect is also provided. The method can include a step of applying the bone graft composition to a subject having the bone defect, such as a spinal bone defect. The subject receiving the bone graft composition can be a mammal, namely a human, pet, or domestic animal.

Disclosed is a method for forming an orthopaedic implant. The method comprises determining one or more parameters of a bone, of a subject, to which the implant is to be attached, and calculating specifications based on parameters. That calculation includes calculating a mechanical property relating to elasticity of the implant, a length of the implant, and positions of two or more fixation locations by which to fix the implant to the bone. The method further comprises forming the implant based on the specifications, wherein each fixation location comprises a longitudinal axis through the implant, and calculating specifications comprises calculating a trajectory for the longitudinal axis of the respective fixation location.

A bone implant holding and shaping tray is provided. The tray includes a first segment having a distal end and a first surface sized to hold and shape at least a portion of the bone implant with bone material. The tray includes a second segment having a second surface sized to hold and shape at least a portion of the bone implant with bone material, the second segment having a proximal end configured to be coupled to the distal end of the first segment so as to extend the first surface to hold and shape the bone implant. Methods of making and using the bone implant holding and shaping tray are also provided.

Disclosed herein are methods of producing a cartilaginous implant by producing a polymer scaffold composition by electrospinning a polymer solution onto a collector in order to obtain polymer fibers; crosslinking the polymer fibers; and adding a plurality of cells to the polymer scaffold composition, wherein the plurality of cells comprises cartilaginous cells to form a cartilaginous implant.

Methods of bioprinting a bio-ink construct on an internal tissue defect or a chondral defect during a minimally invasive surgery on an individual in need thereof are provided, comprising: visualizing the defect; positioning a bioprinter comprising a printhead within proximity of or in contact with the defect; and ejecting a bio-ink from the printhead onto the defect to form a bio-ink layer, thereby generating a bio-ink construct. Further provided are systems for bioprinting a bio-ink construct on an internal tissue defect during a minimally invasive surgery on an individual in need thereof, comprising a control system, an endoscope, and a bioprinter comprising a printhead.

Methods, systems and devices for pre-operatively planned total or partial joint surgery including, for example, anatomic and reverse shoulder surgery guides and implants. There are also methods for pre-operative planning methods for designing glenoid implants and prostheses, particularly with patient-specific augmentation, based on considerations of multiple factors affecting the outcome of a selected reverse or anatomic shoulder surgery. There are also described methods of performing total or partial joint surgery, including anatomic or reverse shoulder surgery, using surgery guides and implants in patients undergoing joint surgery.

The biocompatible lattice structures and implants disclosed herein have an increased or optimized lucency, even when constructed from a metallic material. The lattice structures can also provide an increased or optimized lucency in a material that is not generally considered to be radiolucent. Lucency can include disparity, maximum variation in lucency properties across a structure, or dispersion, minimum variation in lucency properties across a structure. The implants and lattice structures disclosed herein may be optimized for disparity or dispersion in any desired direction. A desired direction with respect to lucency can include the anticipated x-ray viewing direction of an implant in the expected implantation orientation.

A hip implant is provided that includes a metal acetabular cup to be inserted into an acetabulum of the pelvis, a femoral head and neck portion with a polymer femoral head molded onto a metal formal head base that is attached to a metal femoral neck rod configured to be inserted into the neck of a femur, and a metal main body shaft configured to be inserted into a femoral shaft region of the femur and secured by bone screws. The head base may have stabilizing features, such as dimples and peripheral mounds, over which the femoral head is molded. The main body shaft also has diagonal hole located at the center line of the neck of the femur to receive the femoral neck rod at an adjustable angle. The femoral head interfaces with the acetabular cup as a smooth plastic-to-metal spherical-surface joint.

The invention relates to a bone implant, comprising a main body, which has, in its outer region, an open-cell porous lattice structure, which is formed from a plurality of regularly arranged elementary cells, the elementary cells being in the form of an assembled structure and each being composed of an interior and of a plurality of interconnected bars surrounding the interior. The porous lattice structure is provided with a bone-growth-promoting coating comprising calcium phosphate, the calcium phosphate coating having a hydroxylapatite proportion forming a pore inner coating extending into the depth of the porous lattice structure.