The disclosure relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotide molecules comprising an mRNA encoding an OX40L polypeptide. Also provided is a method for activating T cells or increasing the number of NK cells in a subject in need thereof.

A method for exchange of equipment performance data includes the steps of: obtaining performance data of a communicatively-insulated device; converting the performance data into a scannable code; capturing an image of the scannable code; decoding the scannable code using a communicatively-enabled device to extract an address string encoded in the scannable code, the address string comprising an address of a remote server and the performance data; initiating, by the communicatively-enabled device, a communications link with the remote server using the address string thereby to provide the performance data to the remote server; performing, by the remote server, analytics on the performance data; and sending historic device performance data and/or analytical results to a remote computing device and/or sending a link to the historic device performance data and/or analytical results to the remote computing device; wherein the communicatively-insulated device is medical imaging equipment and wherein obtaining the performance data comprises scanning a phantom using the medical imaging equipment and/or acquiring medical imaging equipment sensor data and generating a system status report identifying one or more operational parameters of the medical imaging equipment.

When a restart event is detected within a technology landscape, restart-impacted performance metrics and non-restart-impacted performance metrics may be identified. The non-restart-impacted performance metrics may continue to be included within a performance characterization of the technology landscape. The restart-impacted performance metrics may be monitored, while being excluded from the performance characterization. The restart-impacted performance metric of the restart-impacted performance metrics may be transitioned to a non-restart-impacted performance metric, based on a monitored value of the restart-impacted performance metric following the restart event.

A system for monitoring a computing platform configured to receive a particular metric from metrics associated with the computing platform. A plurality of layers of the computing platform are monitored. Monitoring parameters of the plurality of layers of the plurality of layers are determined. Heuristics of each monitoring parameter are determined over a time period. Monitoring packages are created from the monitoring parameters based on correlations between groups of monitoring parameters, the plurality of layers, and the metrics. Based on the particular metric, a string of monitoring packages is dynamically created from the monitoring packages. A behavior of the particular metric is determined in a configurable time duration in the future using the dynamically created string of monitoring packages. Possible failures of the computing platform related to the particular metric are predicted in an environment of the computing platform based on the determined behavior of the particular metric.

An information handling system includes a corrosion controller that may monitor a corrosion sensor array, and determine a type of the corrosion based on a location of a corrosion sensor. The corrosion type may include humidity driven corrosion and non-humidity driven corrosion.

The disclosure relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotide molecules comprising an mRNA encoding an OX40L polypeptide. Also provided is a method for activating T cells or increasing the number of NK cells in a subject in need thereof.

In one embodiment, a method includes accessing a loaded but paused source process executable and disassembling the source process executable to identify a system call to be instrumented and an adjacent relocatable instruction. Instrumenting the system call includes building a trampoline for the system call that includes a check flag instruction at or near an entry point to the trampoline and two areas of the trampoline that are selectively executed according to results of the check flag instruction. Building a first area of the trampoline includes providing instructions to execute a relocated copy of the adjacent relocatable instruction and return flow to an address immediately following the adjacent relocatable instruction. Building a second area of the trampoline includes providing instructions to invoke at least one handler associated with executing a relocated copy of the system call and return flow to an address immediately following the system call.

Techniques for monitoring operating statuses of an application and its dependencies are provided. A monitoring application may collect and report the operating status of the monitored application and each dependency. Through use of existing monitoring interfaces, the monitoring application can collect operating status without requiring modification of the underlying monitored application or dependencies. The monitoring application may determine a problem service that is a root cause of an unhealthy state of the monitored application. Dependency analyzer and discovery crawler techniques may automatically configure and update the monitoring application. Machine learning techniques may be used to determine patterns of performance based on system state information associated with performance events and provide health reports relative to a baseline status of the monitored application. Also provided are techniques for testing a response of the monitored application through modifications to API calls. Such tests may be used to train the machine learning model.

In one embodiment, a device executes a segment of machine code for an application in a write-protected memory of the device. The executed segment of machine code includes instrumentation instructions that capture a performance measurement for the application. The device changes the write-protected memory of the device to be writable. The device overwrites a first instruction at an anchor location in the segment of machine code in the writable memory of the device with a second instruction. The device re-executes the segment of machine code with the second instruction, wherein the second instruction disables execution of the instrumentation instructions.

A method for exchange of equipment performance data includes the steps of: obtaining performance data of a communicatively-insulated device; converting the performance data into a scannable code; capturing an image of the scannable code; decoding the scannable code using a communicatively-enabled device to extract an address string encoded in the scannable code, the address string comprising an address of a remote server and the performance data; and initiating, by the communicatively-enabled device, a communications link with the remote server using the address string thereby to provide the performance data to the remote server.