Ophthalmic devices and ophthalmic systems including alignment sidewalls and blend zones disposed therethrough are described. An example ophthalmic device may include a first and a second optical element having alignment sidewalls shaped to cooperatively couple. The alignment sidewall may include blend zones disposed in the sidewall shaped to transition the sidewall from a ridge to a surface of an optic zone of the optical element. The alignment sidewalls may define a cavity disposed between two coupled optical elements when the alignment sidewalls are cooperatively coupled into which a liquid crystal may be disposed. A method of assembling an ophthalmic device is described. An example method may include aligning a blend zone of a first optical element with a mating blend zone of a second optical element. The example method may further include cooperatively coupling alignment sidewalls of the first optical element and the second optical element.

A stent device including a stent coated with a photosensitizer, the stent including a pair of electrodes; and a circuit fixed to the stent, the circuit including a light emitting diode, a power receiving means for wirelessly receiving power from the outside, and converting the power to electric power; a second communicating means for receiving a control command from the outside; and a second control means for applying, based on the control command, the electric power to the electrodes causing an electric current to flow through the stent between the electrodes, the flow causing heating of the stent, and for controlling a temperature of the stent to provide hyperthermia therapy to a tumor, the second control means further for applying, based on the control command, the electric power to the light emitting diode to emit a predetermined wavelength of light to the photosensitizer to provide photodynamic therapy to the tumor.

The invention relates to an assembly formed by a medical device (1) adapted to be implanted in a human or animal body and by packaging, wherein: te medical device comprises a housing (11) that encloses a fluid reservoir (13) and a fluid outlet (12) forming a fluid connection between the reservoir and a volume outside the housing; the packaging includes a tank (2) comprising a bottom (20), a side wall (21), an upper face opposite the bottom in a vertical direction, and an opening configured to fill the tank with a biocompatible fluid, the bottom (20) of the tank extending in a horizontal plane perpendicularly to the vertical direction; at least one of the bottom, the side wall and the top face comprises a first holding element (201) adapted to hold the housing in the tank, the housing (11) being held in the tank (2) by said first holding element (201) such that the reservoir is located between the bottom of the tank and the fluid outlet, said fluid outlet being arranged below the opening such that the fluid outlet is immersed in the fluid when the tank is filled with the biocompatible fluid.

Disclosed herein is an endoprosthetic spacer (100, 200, 300) for administering a therapeutic treatment, in particular a theragnostic treatment. The endoprosthetic spacer (100, 200, 300) comprises a body (102) that is configured to replace at least a part of a bone, a sensor assembly (104) comprising at least one sensor (104A, 104B, 104C), a communication module (108) configured to transmit a signal; and a controller (106) configured to read out a sensor signal from the at least one sensor (104A, 104B, 104C) and to transmit an output signal (110) via the communication module (108).

A prosthetic disc can take the form of a sensing artificial disc that includes a resilient core and at least one sensor configured to sense one or more conditions within and/or experienced by the disc. The sensing artificial disc can serve as a replacement to a failed or injured disc between two vertebrae of a spine. The sensing artificial disc can include at least one element configured to change a condition or property of the resilient core in response to a condition sensed by the at least one sensor. A prosthetic disc can include therapeutic system configured to deliver medication to the body, which can include a reservoir of medication.

An artificial bladder system including an implantable bladder, a valve, a number of sensors, and an alert mechanism. The implantable bladder includes an outer wall forming a chamber for collecting urine of a user, the outer wall including inflow openings and an outflow opening. The valve is integrated with the outflow opening to selectively allow urine to flow from the chamber through the outflow opening. The sensors are configured to detect a urine level in the chamber. The alert mechanism is configured to generate a sensory output to alert the user that the bladder should be emptied upon detection of the urine level in the chamber by one of the sensors.

An ophthalmic assembly for implantation in an anterior chamber of an eye of a patient to provide accommodation of the vision to said patient comprises a variable-focus lens and an actuator for modifying the focal length of the variable-focus lens. The ophthalmic assembly comprises an autofocus system configured to determine a distance parameter of an object that the patient's eye is looking at; a signal processing unit arranged to convert said distance parameter into a focal length value of the variable-focus lens; and an actuator control unit configured to control the actuator as a function of the focal length value received from said signal processing unit. A method for accommodating the vision of a patient using an opthamalic assembly is also disclosed.

Antibacterial coatings and methods of making the antibacterial coatings are described herein. A first branched polyethylenimine (BPEI) layer is formed and a first glyoxal layer is formed on a surface of the BPEI layer. The first BPEI layer and the first glyoxal layer are cured to form a crosslinked BPEI coating. The first BPEI layer can be modified with superhydrophobic moieties, superhydrophilic moieties, or negatively charged moieties to increase the antifouling characteristics of the coating. The first BPEI layer can be modified with contact-killing bactericidal moieties to increase the bactericidal characteristics of the coating.

Medical devices in accordance with various embodiments of the present invention employ one or more coaxial screw gear sleeve mechanisms. In various embodiments, coaxial screw gear sleeve mechanisms include a post with a threaded exterior surface and a corresponding sleeve configured to surround the post, the corresponding sleeve having a threaded interior surface configured to interface with the threaded exterior surface of the post and a geared exterior surface. A drive mechanism can be configured to interface with the geared exterior surface of the sleeve, causing the device to expand.

A system and method for powering a medical device that includes a fixture configured for periodic patient proximity; external electrical coupling device integrated into the fixture wherein the external electrical coupling device comprises at least one external energy coupler and is configured to detect presence of an electrical medical device implant in a transmission zone of the external electrical coupling device; an electrical medical device implant, wherein the electrical medical device implant comprises at least one implant energy coupler; and wherein the external electrical coupling device is configured to couple to the implantable medical device through a wireless energy transmission between the external energy coupler and the implant energy coupler when presence of the implantable medical device is within a transmission zone.