A tumor tracking system and method which leverages an image generator and an MD6DM model for tracking and monitoring a status of a tumor over time. In particular, the tumor tracking system enables a physician, or a group of physicians, in collaboration, to visualize and interact with an integrated representation of data relating to a patient's tumor and associated treatment history and also to plan future treatments of the tumor. An integrated and interactive tumor board generated by the tumor tracking system provides a single interface that compiles and organizes information from multiple sources to enable efficient tumor tracking and treatment planning.

A method for analyzing a patient based on a volumetric pulmonary scan includes receiving volumetric pulmonary scan data representative of a patient's pulmonary structure. This method also includes determining a level of transpulmonary pressure defining an effort metric based on one or more characteristics from the received volumetric pulmonary scan data. This method further includes determining one or more physiological or anatomical parameters associated with the transpulmonary pressure based on the received volumetric pulmonary scan data and the effort metric. A non-transitory computer readable medium can be programmed with instructions for causing one or more processors to perform the method for analyzing a patient based on a volumetric pulmonary scan.

A method for processing images of lungs, the method comprising defining an inhale region of interest of the lungs at an inhale position and an exhale region of interest of the lungs at an exhale position, determining a spatial transformation of each voxel within the lungs between the lungs at the inhale position and the lungs at the exhale position to provide displacement vector estimates for each voxel within the lungs, and performing volume change inference operations to determine a volume change between the lungs at the inhale position and the lungs at the exhale position based on the inhale region of interest, the exhale region of interest, and the displacement vector estimates for each voxel within the lungs.

The present invention relates to an image processing apparatus for deriving multi-dimensional images of an object and an according system and method. The image processing apparatus comprises an interface configured to provide 3D image data of an object and to provide a sequence of images of the object. The image processing apparatus further comprises a processing unit configured to obtain a personalized 3D model of the object by applying a model-based segmentation to the 3D image data of the object and to adapt the personalized 3D model based on at least a part of the images of the sequence of images of the object.

A method for determining respiratory induced blood mass change from a four-dimensional computed tomography (4D CT) includes receiving a 4D CT image set which contains a first three-dimensional computed tomographic image (3D CT) and a second 3D CT image. The method includes executing a deformable image registration (DIR) function on the received 4D CT image set, and determining a displacement vector field indicative of the lung motion induced by patient respiration. The method further includes segmenting the received 3D CT images into a first segmented image and a second segmented. The method includes determining the change in blood mass between the first 3D CT image and the second 3D CT image from the DIR solution, the segmented images, and measured CT densities.

A system and method for improved image acquisition of multiple pulsed X-ray source-in-motion tomosynthesis imaging apparatus by generating the electrocardiogram (ECG) waveform data using an ECG device. Once a representative cardiac cycle is determined, system will acquire images only at rest period of heart beat. Real time ECG waveform is used as ECG synchronization for image improvement. The imaging apparatus avoids ECG peak pulse for better chest, lung and breast imaging under influence of cardiac periodical motion. As a result, smoother data acquisition, much higher data quality can be achieved. The multiple pulsed X-ray source-in-motion tomosynthesis machine is with distributed multiple X-ray sources that is spanned at wide scan angle. At rest period of one heartbeat, multiple X-ray exposures are acquired from X-ray sources at different angles. The machine itself has capability to acquire as many as 60 actual projection images within about two seconds.

The present invention provides a system and a computer-implemented method for generating at least one 4-dimensional medical image segmentation for at least one structure of a human heart. The method includes the steps of: providing a first n 4-dimensional medical image comprising the at least one structure of the human heart, the medical image being based on a computed tomography scan image; generating a segmentation of at least part of the provided first 4-dimensional medical image using at least one first trained artificial neural network, wherein the at least one first trained artificial neural network is configured as a convolutional processing network with U-net architecture; and generating at least one 4-dimensional medical image segmentation for the at least one structure of the human heart based at least on the segmentation generated by the at least one first trained artificial neural network.

An optical imaging system to image a target object includes a light source configured to emit one or more light rays to illuminate the target object and an image detector configured to capture a three-dimensional topography image of the target object when emitted light is emitted from the target object in response to being illuminated by the light rays emitted by the light source. A fluorescence image detector captures a fluorescence image of the target object when fluorescence is emitted from the target object in response illumination by light rays emitted by the light source. A controller instructs the image detector to capture the 3D topography image and the fluorescence image detector to detect the fluorescence image of the target object intraoperatively and to co-register and simultaneously display intraoperatively the co-registered topography and fluorescence information to the user via a display.

A method of imaging nervous tissue, comprising acquiring functional imaging modality data from a functional imaging modality which images an intrabody volume of a patient having a body part, the patient having been injected with an imaging agent having a nervous tissue uptake by an autonomic nervous system (ANS); and locating the nervous tissue in the intrabody volume based on the functional imaging modality data.

Devices, systems, computer program products and computer implemented methods are provided for dynamically assessing a moving object from a sequence of consecutive volumetric image frames of such object, which images are timely separated by a certain time interval, by: identifying in at least one image of the sequence the object of interest; segmenting the object to identify object contour; propagating the object contour as identified to other images of the sequence; and performing dynamic analysis of the object based on the object contour as propagated.