Embodiments discussed herein facilitate generation of a prognosis for recurrence or non-recurrence of atrial fibrillation (AF) after pulmonary vein isolation (PVI). A first set of embodiments discussed herein relates to training of a machine learning classifier to determine a prognosis for AF after PVI based on radiographic images, alone or in combination with clinical features. A second set of embodiments discussed herein relates to determination of a prognosis for a patient for AF after PVI based on radiographic images, alone or in combination with clinical features.

Disclosed is a method for generating high resolution point cloud data for electro-anatomical mapping comprising receiving sparsely measured point cloud data having a plurality of data points. Surface mesh data comprising mesh points defining triangles on a myocardial surface is generated. The point cloud data is mapped to the surface mesh data. For each point of the surface mesh data that cannot be mapped to the point cloud data because there is a missing data point in point cloud data, an interpolation operation is performed based on the point cloud data within the neighbourhood of the point to generate a value for the missing data point. The interpolation operation is repeated N times. For every repetition, a difference between the value for the missing data point generated from the current iteration and the value for the missing data point generated from the immediately preceding iteration is compared, until the difference is below a threshold.

Method, executed by a computer, for identifying a coronary sinus of a patient, comprising: receiving a 3D image of a body region of the patient; extracting 2D axial images of the 3D image taken along respective axial planes, 2D sagittal images of the 3D image taken along respective sagittal planes, and 2D coronal images of the 3D image taken along respective coronal planes; applying an axial neural network to each 2D axial image to generate a respective 2D axial probability map, a sagittal neural network to each 2D sagittal image to generate a respective 2D sagittal probability map, and a coronal neural network to each 2D coronal image to generate a respective 2D coronal probability map; generating, based on the 2D probability maps, a 3D mask of the coronary sinus of the patient.

A medical system includes an ultrasound probe for insertion into an organ of a body and a processor. The ultrasound probe includes (i) a two-dimensional (2D) ultrasound transducer array, and (ii) a sensor configured to output signals indicative of a position, direction and orientation of the 2D ultrasound transducer array inside the organ. The processor is configured to (a) using the signals output by the sensor, register multiple ultrasound images of a tissue region, acquired over a given time duration by the 2D ultrasound transducer array, with one another, and (b) generate a map of the tissue region indicative of respective amounts of motion of tissue locations in the tissue region.

Systems and methods for determining a concordance between results of medical assessments are provided. Results of a medical assessment of a first type for an anatomical object of a patient and results of a medical assessment of a second type for the anatomical object are received. The results of the medical assessment of the first type are converted to a hemodynamic measure. A concordance analysis between the results of the medical assessment of the first type and the results of the medical assessment of the second type based on the hemodynamic measure is performed. Results of the concordance analysis are output.

A plurality of radiographic images are captured of a portion of a patient in periodic motion, such as cardiac images (heartbeat motion) or lungs (breathing motion). A first subset of the captured radiographic images are identified as having a common first capture time relative to a phase of the periodic motion. A first 3D image is reconstructed using the first subset of captured radiographic images. Additional subsets of the radiographic images are processed similarly based on their common capture time relative to the phase of the periodic motion.

Provided herein are methods and systems for making patient-specific therapy recommendations of a combination of any two or more therapies selected from a lipid-lowering therapy, an anti-inflammatory therapy for patients with known or suspected cardiovascular disease, such as atherosclerosis.

For three-dimensional segmentation from two-dimensional intracardiac echocardiography imaging, the three-dimension segmentation is output by a machine-learnt multi-task generator. The machine-learnt multi-task generator is trained from 3D information, such as a sparse ICE volume assembled from the 2D ICE images. The machine-learnt multi-task generator is trained to output both the 3D segmentation and a complete volume. The 3D segmentation may be used to project to 2D as an input with an ICE image to another network trained to output a 2D segmentation for the ICE image. Display of the 3D segmentation and/or 2D segmentation may guide ablation of tissue in the patient.

Embodiments of the present disclosure include a method, device and computer readable medium involving receiving image data of one or more coronary arteries, generating a binary segmentation indicating presence of calcium in the one or more coronary arteries from the image data, generating a branch density of the one or more coronary arteries, and assigning a coronary artery label from the branch density to the binary segmentation such that at least one indication of presence of calcium of the binary segmentation is labeled as present in a specific one of the one or more coronary arteries.

Systems and methods for detecting aortic aneurysms using ensemble based deep learning techniques that utilize numerous computed tomography (CT) scans collected from numerous de-identified patients in a database. The system includes software that automates the analysis of a series of CT scans as input (in DICOM file format) and provides output in two dimensions: (1) ranking CT scans by risks of adverse events from aortic aneurysm, (2) providing aortic aneurysm size estimates. A repository of CT scans may be used for training of deep neural networks and additional data may be drawn from localized patient information from institutions and hospitals which grant permission.