The disclosure herein relates to systems, methods, and devices for medical image analysis, diagnosis, risk stratification, decision making and/or disease tracking. In some embodiments, the systems, devices, and methods described herein are configured to analyze non-invasive medical images of a subject to automatically and/or dynamically identify one or more features, such as plaque and vessels, and/or derive one or more quantified plaque parameters, such as radiodensity, radiodensity composition, volume, radiodensity heterogeneity, geometry, location, and/or the like. In some embodiments, the systems, devices, and methods described herein are further configured to generate one or more assessments of plaque-based diseases from raw medical images using one or more of the identified features and/or quantified parameters.

A blood vessel detecting apparatus and an image-based blood vessel detecting method are provided. In the method, first to-be-evaluated data is detected through a first detecting model to obtain a first detection result. Second to-be-evaluated data is detected through a second detecting model to obtain a second detection result. The first to-be-evaluated data includes one or more medical images obtained from photographing a blood vessel. The first detection result output by the first detecting model includes one or more pixels in the medical image belonging to the blood vessel. The first detecting model and the second detecting model are constructed based on a machine learning algorithm. The second to-be-evaluated data includes the first detection result. The second detection result output by the second detecting model includes one or more pixels in the medical image belonging to the blood vessel.

Aspects of the disclosure provide for methods, systems, and apparatuses, including computer-readable storage media, for lipid detection by identifying fibrotic caps in medical images of blood vessels. A method includes receiving one or more input images of a blood vessel and processing the one or more input images using a machine learning model trained to identify locations of fibrotic caps in blood vessels. The machine learning model is trained using a plurality of training images each annotated with locations of one or more fibrotic caps. A method includes identifying and characterizing fibrotic caps of lipid pools based on differences in radial signal intensities measured at different locations of an input image. A system can generate one or more output images having segments that are visually annotated representing predicted locations of fibrotic caps covering lipidic plaques.

The present invention teaches a method of predicting the potential for manifestation of various medical conditions by analyzing human placenta comprising and including determining the need for early monitoring, intervention or potential treatment for medical conditions likely to manifest as a child grows older and investigating the potential for various medical conditions. The method includes selecting and identifying a sample of the placenta to analyze by algorithms and preparing the sample to be analyzed. The sample is captured by obtaining a three-dimensional digital image of the chorionic surface of the sample by a selected capturing device. The physician corrects for errors in the digital image and loads the data into a computer for analysis. The digital image data is analyzed using algorithms to determine the vascular structure of the placenta, which is interpreted and analyzed to determine the potential for manifestation of various medical conditions.

A system for automated comprehensive assessment of clinical lumbar MRIs includes a MRI standardization component that reads MRI data from raw lumbar MRI files, uses an artificial intelligence (AI) model to convert the raw MRI data into a standardized format. A core assessment component automatically generates MRI assessment results, including multi-tissue anatomical annotation, multi-pathology detection and multi-pathology progression prediction based on the structured MRI data package. The core assessment component contains a semantic segmentation module that utilizes a deep learning artificial intelligence (AI) model to generate an MRI assessment results that contains multi-tissue anatomical annotation, a pathology detection module to generate multi-pathology detection, and a pathology progression prediction module to generate multi-pathology progression prediction. A model optimization component archives clinical MRI data and MRI assessment results based on comments provided by a specialist, and periodically optimizes the AI deep learning model of the core assessment component.

Systems and methods for image space control of a medical instrument are provided. In one example, a system is configured to display a two-dimensional medical image including a view of at least a distal end of an instrument. The system can determine, based on one or more fiducials on the instrument, a roll estimate of the instrument. The system further can receive a user input comprising a heading command to change a heading of the instrument within a plane of the medical image, or an incline command to change an incline of the instrument into or out of the plane of the medical image. Based on the roll estimate and the user input, the system can generate one or more motor commands configured to cause a robotic system coupled to the medical instrument to move the robotic medical instrument.

A marker-coordinate detecting unit detects coordinates of a stent marker on a new image when the new image is stored in an image-data storage unit; and then a correction-image creating unit creates a correction image from the new image through, for example, image transformation processing, so as to match up the detected coordinates with reference coordinates that are coordinates of the stent marker already detected by the marker-coordinate detecting unit in a first frame. An image post-processing unit then creates an image for display by performing post-processing on the correction image created by the correction-image creating unit, the post-processing including high-frequency noise reduction filtering-processing, low-frequency component removal filtering-processing, and logarithmic-image creating processing; and then a system control unit performs control of displaying a moving image of an enlarged image of a set region that is set in the image for display, together with an original image.

Systems and methods for performing motion artifact correction in medical images. One method includes receiving, with an electronic processor, a medical image associated with a patient, the medical image including at least one motion artifact. The method also includes applying, with the electronic processor, a model developed using machine learning to the medical image for correcting motion artifacts, the model including at least one of a spatial transformer network and an attention mechanism network. The method also includes generating, with the electronic processor, a new version of the medical image, where the new version of the medical image at least partially corrects the at least one motion artifact.

There is provided a computer implemented method for generating a three dimensional (3D) image based of fluorescent illumination, comprising: receiving in parallel by each of at least three imaging sensors positioned at a respective parallax towards an object having a plurality of regions with fluorescent illumination therein, a respective sequence of a plurality of images including fluorescent illumination of the plurality of regions, each of the plurality of images separated by an interval of time; analyzing the respective sequences, to create a volume-dataset indicative of the depth of each respective region of the plurality of regions; and generating a 3D image according to the volume-dataset.

The present disclosure provides a method, device, computer apparatus, and storage medium for training recognition model and recognizing fundus features. The method includes: obtaining a color fundus image sample associated with a label value, inputting the color fundus image sample into a preset recognition model containing initial parameters; extracting a red channel image; inputting the red channel image into the first convolutional neural network to obtain a first recognition result and a feature image of the red channel image; combining the color fundus image sample with the feature image to generate a combined image, and inputting the combined image into the second convolutional neural network to obtain a second recognition result; obtaining a total loss value through a loss function, and when the total loss value is less than or equal to a preset loss threshold, ending the training of the preset recognition model.