An implant includes a frame comprising a tubular body formed by a plurality of interconnected struts that are manufactured to reduce stresses and strains resulting from component interaction during chronic use. At least a portion of a longitudinal corner of one or more struts of the frame may be chamfered, rounded, or otherwise modified to distribute stresses experienced at the strut corner throughout the strut body. Chamfering and/or rounding corners along at least a portion of a strut of the frame may reduce stresses on the frame caused by interactions between the frame and other components of the implant. The implant may be manufactured by cutting (e.g., laser cutting) a plurality of struts from a tubular metal alloy, polymer, or the like forming the tubular body, and softening at least a portion of an edge of the strut by cutting, grinding, and/or micro-blasting the edges of the corner.

The invention is directed to a system and methods for treating neurovascular compression. Certain preferred embodiments of the invention generally comprise an apparatus having an elongated body portion including a proximal anchor element and distal anchor element. The apparatus also may include one or more marker elements to facilitate placement of the apparatus by the user. The apparatus may be configured to permit the user, after insertion and deployment of the apparatus in a blood vessel, to move the blood vessel so that the blood vessel is no longer in contact with and compressing a nerve or other parts of the nervous system.

A kit of stents and an adjustable multi-lumen stent for adjustable interventional reduction of blood flow in a blood vessel. The kit includes: a first reduction stent having in an expanded conformation at least one widened section and a narrowed section, the narrowed section defining a central lumen providing reduced fluid communication between an upstream end and a downstream end of the first reduction stent; at least one expandable dilatation stent having a tubular form insertable into and expandable in the central lumen of the first reduction stent to define an enlarged central lumen; at least one second reduction stent having a narrowed tubular section insertable into the central lumen of the first reduction stent or the central lumen of the dilatation stent to define an reduced central lumen, and having an anchoring element at its upstream end.

A stent includes a cylindrical main body portion, a linkage portion, and a marker attachment portion. The main body portion extends in an axial direction. The linkage portion extends from an end of the main body portion in the axial direction. The marker attachment portion is linked to the main body portion through the linkage portion. The linkage portion includes a bent portion tilting the marker attachment portion outward in a radial direction of the main body portion.

Methods and apparatuses relate to treating vessels that have developed an aneurysm or vessels that are expected to develop an aneurysm (e.g., aortic aneurysm). The device may include a conduit having one or more coupling members that serve to couple the conduit and the vessel together. The conduit and coupling member(s) may cooperate to apply an inward radial force (e.g., physical pulling of the vessel wall inward) on the vessel wall, substantially preventing vessel enlargement. In some embodiments, coupling members are disposed at a midpoint region between opposite ends of the conduit, such as regularly along the length of the conduit. When deployed, the device reduces the risk of excessive vessel enlargement which may otherwise lead to undesirable rupture or dissection of the vessel.

An intravascular cell therapy device comprises a scaffold (2, 12) that is radially adjustable between a contracted orientation suitable for transluminal delivery to a vascular locus and an expanded orientation, and a biodegradable matrix provided on at least a portion of the scaffold that is suitable for seeding with cells and degrades in a vascular environment. The scaffold is configured to have a distal piercing tip (5) when in a deployed orientation. The scaffold comprises a plurality of sidewall panels (3, 13, 14) arranged around a longitudinal axis of the scaffold, and adjustable couplings (4) between the panels configured for adjustment between an expanded configuration and a contracted orientation, and in which each sidewall panel comprises a matrix suitable for seeding with cells.

A filter device for implantation in a gallbladder, comprising: a filter portion configured to filter gallstones of a certain minimum size to prevent them from exiting the gallbladder through an opening of the gallbladder; a blocking portion configured to push gallstones of a certain minimum size away from an opening of the gallbladder where the blocking portion is located distally from the filter portion with respect to the opening of the gallbladder; and, where the blocking portion and the filter portion do not attach to, or apply expansive radial force on, a wall of the gallbladder.

The present embodiments provide a stent for use in a medical procedure that comprises a series of proximal apices disposed at a proximal end of the stent and a series of distal apices disposed at a distal end of the stent. In a first embodiment, a first proximal apex comprises a bore for receiving a trigger wire, and a second proximal apex, disposed adjacent to the first proximal apex, comprises at least one barb. In an alternative embodiment, a first proximal apex comprises a first bore and a second, adjacent proximal apex comprises a second bore, such that a single trigger wire may be disposed through the first and second bores to restrain the first and second proximal apices during delivery.

An endoprosthesis may include an expandable framework including an anchoring portion and a body portion extending axially from the anchoring portion, the body portion having a plurality of body cells; and a polymeric cover disposed on at least a portion of the expandable framework. The anchoring portion includes a first transverse flange and a second transverse flange proximate the first transverse flange, the first and second transverse flanges being configured to secure the anchoring portion at an orifice of a body lumen. The body portion includes a window through a side of the body portion, the window occupying space equivalent to at least two of the plurality of body cells. The window is devoid of the polymeric cover and any other structure within a perimeter of the window.

A stent graft includes a tubular aortic component that defines a lumen and a fenestration with a pocket at the fenestration. At least one proximal tunnel graft extends proximally within the lumen from the proximal opening of the pocket and is secured at a proximal end to the tubular component, and at least one distal tunnel graft extends distally within the lumen from the distal opening of the pocket and is secured at a distal end to the tubular aortic component. The stent graft can further include at least one branch stent graft, each of which extends through the fenestration and within at least one of the proximal tunnel graft or the distal tunnel graft. The stent graft can be implanted in a patient to thereby treat an aneurysm, such as a suprarenal or thoracoabdominal aortic aneurysm.