A diametric adjustment mechanism for an implantable medical device including a track defining a series of diametric setpoints, including a first diametric setpoint and a second diametric setpoint, a rider engaged with the track such that the rider is selectively movable along the track from the first diametric setpoint to the second diametric setpoint and from the second diametric setpoint to the first diametric setpoint, and a biasing element biasing the rider toward the first diametric setpoint when the rider is at the second diametric setpoint.

Provided herein are systems and methods for creating and deploying an entirely extraluminal enterogenesis device that is actuated during the enterogenesis period after the surgery is completed via an automatically controlled in-vivo activation of shape memory polymer network. This enterogenesis device operates to grow an extended body lumen without any significant interventions (e.g., via additional surgical intervention) over the period of lumen lengthening. Furthermore, the enterogenesis device operates outside the body lumen to lengthen the lumen without interfering with the lumen's internal activity during the period of the enterogenesis. The extraluminal enterogenesis device operates in an automatically-controlled manner over an extended period of time to provide the correct stimulus to grow the lumen into a lengthened state during the enterogenesis treatment period while providing high-quality continuous lumen activity during the treatment period without further intervention before distraction treatment is completed.

Provided herein are systems and methods for creating and deploying an entirely extraluminal enterogenesis device that is actuated during the enterogenesis period after the surgery is completed via an automatically controlled in-vivo activation of shape memory polymer network. This enterogenesis device operates to grow an extended body lumen without any significant interventions (e.g., via additional surgical intervention) over the period of lumen lengthening. Furthermore, the enterogenesis device operates outside the body lumen to lengthen the lumen without interfering with the lumen's internal activity during the period of the enterogenesis. The extraluminal enterogenesis device operates in an automatically-controlled manner over an extended period of time to provide the correct stimulus to grow the lumen into a lengthened state during the enterogenesis treatment period while providing high-quality continuous lumen activity during the treatment period without further intervention before distraction treatment is completed.

A delivery apparatus can include a handle portion and at least one rotatable drive shaft. The handle portion has an actuation mechanism. The actuation mechanism includes a motor and one or more actuators. The rotatable drive shaft has a proximal end portion and a distal end portion. The proximal end portion is coupled to the motor, and the distal end portion is configured to be releasably coupled to a prosthetic heart valve. The actuation mechanism is configured to control and monitor expansion of the prosthetic heart valve. The handle is configured for actuating the actuation mechanism, tracking a response of native tissue when the prosthetic heart valve is in contact with the native tissue, and stopping expansion of the prosthetic heart valve once a rate of change of expansion of the prosthetic heart valve declines below a threshold.

A delivery apparatus can include a handle portion and at least one rotatable drive shaft. The handle portion has an actuation mechanism. The actuation mechanism includes a motor and one or more actuators. The rotatable drive shaft has a proximal end portion and a distal end portion. The proximal end portion is coupled to the motor, and the distal end portion is configured to be releasably coupled to a prosthetic heart valve. The actuation mechanism is configured to control and monitor expansion of the prosthetic heart valve. The handle is configured for actuating the actuation mechanism, tracking a response of native tissue when the prosthetic heart valve is in contact with the native tissue, and stopping expansion of the prosthetic heart valve once a rate of change of expansion of the prosthetic heart valve declines below a threshold.

An esophageal atresia bridge device including a proximal anchor, a distal anchor, and a brace extending between the proximal anchor and the distal anchor. The brace permits the proximal anchor to move toward the distal anchor to apply a controlled tension that pulls the esophagus together and stretches the esophagus over time. A method of treating esophageal atresia may include inserting an elongate member of an esophageal atresia device into a mouth of a patient, the esophageal atresia device including a rotatable member including a threaded region, and rotating the rotatable member relative to the elongate member to longitudinally move the distal end of the elongate member relative to the rotatable member in order to apply a force to a proximal pouch of the patient's esophagus.

An esophageal atresia bridge device including a proximal anchor, a distal anchor, and a brace extending between the proximal anchor and the distal anchor. The brace permits the proximal anchor to move toward the distal anchor to apply a controlled tension that pulls the esophagus together and stretches the esophagus over time. A method of treating esophageal atresia may include inserting an elongate member of an esophageal atresia device into a mouth of a patient, the esophageal atresia device including a rotatable member including a threaded region, and rotating the rotatable member relative to the elongate member to longitudinally move the distal end of the elongate member relative to the rotatable member in order to apply a force to a proximal pouch of the patient's esophagus.

Excessive dilation of the annulus of a mitral valve may lead to regurgitation of blood during ventricular contraction. This regurgitation may lead to a reduction in cardiac output. Disclosed are systems and methods relating to an implant configured for reshaping a mitral valve. The implant comprises a plurality of struts with anchors for tissue engagement. The implant is compressible to a first, reduced diameter for transluminal navigation and delivery to the left atrium of a heart. The implant may then expand to a second, enlarged diameter to embed its anchors to the tissue surrounding and/or including the mitral valve. The implant may then contract to a third, intermediate diameter, pulling the tissue radially inwardly, thereby reducing the mitral valve and lessening any of the associated symptoms including mitral regurgitation.

A braided stent system includes a stent body having a lumen formed by a plurality of braided members with interstices formed therebetween and a first expansion ring connected to the lumen of the stent body. The first expansion ring may include a frame defined by a plurality of interconnected support assemblies that are selectively positioned to impart an outwardly expanding radial force to the stent body, each support assembly can include a plurality of legs joined at a first intersection and connected to one of the other interconnected support assemblies at a second intersection opposite the first intersection. Each support assembly can include a claw portion mechanically connected to one or more of the interstices of the stent body so that the frame imparts an outward radial expansion force of the stent to facilitate use and delivery of the stent.

A delivery apparatus comprises a handle portion and at least one rotatable drive shaft. The handle portion has an actuation mechanism and a display. The actuation mechanism includes a motor and one or more actuators. The rotatable drive shaft has a proximal end portion and a distal end portion. The proximal end portion is coupled to the motor, and the distal end portion is configured to be releasably coupled to a prosthetic heart valve. The actuation mechanism is configured to control and monitor expansion of the prosthetic heart valve, and the display is configured to display a diameter of the prosthetic heart valve.