A medical stent having a first end, a second end, and a central longitudinal axis extending from the first end to the second end, may include a plurality of first filaments each extending in a first helical path around the central longitudinal axis in a first direction and a plurality of second filaments each extending in a second helical path around the central longitudinal axis in a second direction. The plurality of first filaments may be interwoven with the plurality of second filaments. The first helical path of at least one of the plurality of first filaments may include a circumferential offset disposed between the first end and the second end.

Expandable medical devices, including implantable medical devices that expand, such as stents and anchors, may be selectively expanded to for treatment purposes, including to hold the expandable medical devices and/or other devices with which the expandable medical devices are used in place within the body of a subject (e.g., within a vessel, a duct, another tubular organ, etc.). Such an expandable medical device may include struts that rotate outwardly as the expandable medical device expands. As the struts rotate outwardly, they may engage a surface against which the expandable medical device is expanded, holding the expanded expandable medical device in place. The expandable medical device may also plastically deform upon while expanded, enabling it to remain in an expanding state once an expanding force is no longer applied thereto.

An endoluminal device can comprise a flexible tubular wall and a frame member. The frame member can be comprised of a shape-memory material having sides with protrusions which are partially or substantially flattened when formed together with the flexible tubular wall to thereby create a bias in the side wall of the endoluminal device that resists deformation from a desired device profile during crush loading and is thereby resistant to invaginations when deployed.

Storage devices, loading devices, delivery systems, kits, and associated methods for implantable medical devices are described. An example embodiment of a storage device includes a storage member, a first cap, and a second cap. The storage member has a first end, a second end, and a main body that defines a first opening, a second opening, a passageway, a separating wall, and a plurality of holes. The passageway has a first portion and a second portion. The first portion extends from the first end of the storage member to the separating wall and the second portion extends from the second end of the storage member to the separating wall. Each hole of the plurality of holes extends through the separating wall and provides access between the first portion and the second portion. Each of the first and second caps is releasably attached to the storage member.

An endoprosthesis delivery system includes a wire holder on a distal section of an elongated shaft with a plurality of wires extending distally from the wire holder and, in a secured position, terminating in a distal receiver attached to the elongated shaft distal to the wire holder. A single wire attached to the wire holder and extending proximally along the delivery system to a point easily accessible by the operator may be pulled proximally to move the wires out of the distal receiver and release the endoprosthesis.

A method for implanting a prosthesis centrally within a curved lumen includes loading a prosthesis into a delivery sheath, advancing the sheath in a patient towards the curved lumen to place at least the proximal end of the prosthesis within the curved lumen, and centering the proximal end of the prosthesis and/or the distal end of the sheath within the curved lumen. In a first advancing step, the outer catheter containing the inner sheath is advanced together towards the curved lumen to a location proximal of the curved lumen and, in a second advancing step, the inner sheath containing the prosthesis is advanced into the curved lumen to place at least the proximal end within the curved lumen while the outer catheter substantially remains at the location. After centering, the proximal end of the prosthesis is deployed centered within the curved lumen.

An endoluminal device can comprise a flexible tubular wall and a frame member. The frame member can be comprised of a shape-memory material having sides with protrusions which are partially or substantially flattened when formed together with the flexible tubular wall to thereby create a bias in the side wall of the endoluminal device that resists deformation from a desired device profile during crush loading and is thereby resistant to invaginations when deployed.

A graft compression system for compressing soft tissue grafts used in connection with reconstructive surgery on the anterior cruciate ligament (ACL). The graft compression system includes a compression chamber having an elongate hollow shaft body having two ends that are threaded to mate with correspondingly threaded collet nuts. Collets are removably inserted into, and engage, the collet nuts fastened to opposing ends of the compression chamber A surgical graft may be inserted into a hollow compression tube having a lumen with a compressible diameter, said compression tube being sized for insertion into the collets and compression chamber. When such collet nuts are tightened by a user of the graft compression system, the inner diameters of the respective collet nuts nested within such collet nuts are decreased, causing the diameter of the lumen of the hollow compression tube to in turn be decreased and compress the surgical graft within.

An endoprosthesis delivery system includes a wire holder on a distal section of an elongated shaft with a plurality of wires extending distally from the wire holder and, in a secured position, terminating in a distal receiver attached to the elongated shaft distal to the wire holder. A single wire attached to the wire holder and extending proximally along the delivery system to a point easily accessible by the operator may be pulled proximally to move the wires out of the distal receiver and release the endoprosthesis

Medical device loading apparatuses, systems, methods and kits are described. A loading apparatus comprises a main body having a proximal end defining a proximal opening, a distal end defining a distal opening, and a passageway extending between the proximal and distal openings. The passageway defines a proximal chamber having a first inner diameter, a distal chamber having a second inner diameter, and a transition chamber disposed between the proximal and distal chambers. The transition chamber has an inner diameter that transitions from the larger second inner diameter to the smaller first inner diameter. The main body has a separable connection that divides the main body between proximal and distal portions when disrupted. An expandable intraluminal medical device can be loaded into a delivery catheter using the loading apparatus by placing the device into the passageway such that it is in a radially-expanded configuration; pulling the device along an axial path through the loading apparatus such that the device transitions from the radially-expanded configuration to a radially-compressed configuration; and pushing the radially-compressed device along the axial path into the delivery catheter.