A delivery device can include several different features including, at least: a shuttle and trigger retraction of an outer sheath; an interlock device to prevent actuation of the trigger; a retraction override switch and lock; and an inner shaft adjuster to ensure correct alignment of the inner shaft and the outer sheath prior to device deployment. The inner shaft adjuster may include, at least: a proximal portion of the handle housing having slots therethrough: pins operatively fixed to the inner shaft and extending through and slidable within the slots: and a cap having an inner helical groove that mates with the pins. Rotation of the cap may push the pins and the inner shaft in a proximal-distal direction. The cap may have a distal lip configured to accept a proximal extension of the interlock and retain it in a locked position until the inner shaft has been adjusted or moved.

Distal tips for use with delivery catheters are disclosed that are configured to facilitate deflection of the catheters as they are advanced through the vasculature to a desired treatment site. Distal tips so configured realize one or more of the objectives of safer, more accurate steering of the catheter through the vasculature.

Aspects of the disclosure include delivery devices for transcatheter delivery of a cardiac implant. Delivery devices can include a handle assembly as well as a piston mount connected to the handle assembly and having a distal portion terminating at a nose cap. The distal portion includes a stop extending radially from and fixed to the distal portion. The delivery device further includes a capsule assembly including a biasing element for selectively sheathing the implant and a plurality of retraction members secured about a distal end of the biasing element to control deployment of the implant. In various examples, the biasing element is a helical compression spring and the implant is a prosthetic tricuspid heart valve. Methods of loading a delivery device and delivering an implant are also disclosed.

A stent delivery device that can be inserted into an endoscope. The device includes a guide catheter including a guide tube, an operating wire, and a joint portion that joins the guide tube and the wire. The device also includes a pusher catheter including a first tube through which the wire is inserted and a second tube through which the guide tube is inserted. The device may include a bite prevention portion that can prevent the wire from biting into an inner surface of the second tube. In a state where a distal end of the pusher catheter protrudes from the endoscope channel and the channel includes a curved portion in a curved state, a proximal end of the guide tube, which includes the joint portion, and/or the bite prevention portion can be positioned proximal of a proximal end of the curved portion in the endoscope channel.

Intravascular delivery systems, devices, and methods are disclosed herein. A representative delivery device can include an inner shaft defining a lumen extending along a length of the delivery device, an outer shaft surrounding the inner shaft along at least a portion of the length of the delivery device, and a tip portion distal to the outer shaft. The inner shaft can include a recess configured to receive a self-expandable implant. The outer shaft can be retractable relative to the inner shaft, and can include a functional member that provides increased tensile strength to the outer shaft, and a coil. The tip portion can extend to a distal terminus of the delivery device and include a cross-sectional dimension that tapers in a distal direction.

A stent delivery device that can be inserted into an endoscope. The device includes a guide catheter including a guide tube, an operating wire, and a joint portion that joins the guide tube and the wire. The device also includes a pusher catheter including a first tube through which the wire is inserted and a second tube through which the guide tube is inserted. The device may include a bite prevention portion that can prevent the wire from biting into an inner surface of the second tube. In a state where a distal end of the pusher catheter protrudes from the endoscope channel and the channel includes a curved portion in a curved state, a proximal end of the guide tube, which includes the joint portion, and/or the bite prevention portion can be positioned proximal of a proximal end of the curved portion in the endoscope channel.

Intravascular delivery systems, devices, and methods are disclosed herein. A representative delivery device can include an inner shaft defining a lumen extending along a length of the delivery device, an outer shaft surrounding the inner shaft along at least a portion of the length of the delivery device, and a tip portion distal to the outer shaft. The inner shaft can include a recess configured to receive a self-expandable implant. The outer shaft can be retractable relative to the inner shaft, and can include a functional member that provides increased tensile strength to the outer shaft, and a coil. The tip portion can extend to a distal terminus of the delivery device and include a cross-sectional dimension that tapers in a distal direction.

The present technology is directed to devices, systems, and methods for improving pulmonary function in a human subject. The present technology includes a robotic system configured to assist in delivery and deployment of an implant in an airway of a patient. The robotic system can comprise a workstation for engaging with and receiving instructions from a treatment provider and an arm in operative communication with the workstation. The arm can comprise an instrument driver and an articulatable instrument. The articulatable instrument can comprises an elongate member having a proximal portion coupled to the instrument driver, a distal portion configured for positioning in a bronchial airway of the human subject, and a working channel extending from the proximal portion to the distal portion. The working channel can be configured to receive a delivery system containing the airway implant therethrough.

A delivery catheter comprises an inner shaft and an outer sheath. A stent-graft is held on a region of the inner shaft. An enlarged diameter distal region of the outer sheath constrains the stent-graft. Its retraction allows the stent-graft to deploy. A finger wheel on a handle is used to retract the outer sheath and is coupled to a sliding block with cable(s). The sliding block is coupled to the outer sheath and is held within a sliding track. The wheel can be actuated to tension the cable(s) and deform latch(es) coupled to sliding block, freeing them from slot(s) in the sliding track and allowing retraction of the sliding block and the outer sheath. A reinforcement sleeve is coupled to a smaller diameter proximal region of the outer sheath. A gap between the outer sheath distal region and the reinforcement sleeve allows the distal outer shaft region to be retracted.

A method for manufacturing a tube, comprising the steps of: disposing a first inner cylindrical body (11) and a second inner cylindrical body (12) side by side in a longitudinal direction; disposing a reinforcing layer (13) composed of wire from an outer side of the first inner cylindrical body (11) to an outer side of the second inner cylindrical body (12); disposing an outer layer (14) on an outer side of the reinforcing layer (13) to obtain a tube precursor (15); and heating the tube precursor (15); wherein: a melting point or decomposition point of a resin constituting the first inner cylindrical body (11) is higher than a melting point of a resin constituting the second inner cylindrical body (12) and a melting point of a resin constituting the outer layer (14); and a heating temperature in the step of heating the tube precursor (15) is equal to or higher than the melting point of the resin constituting the second inner cylindrical body (12) and the melting point of the resin constituting the outer layer (14), and lower than the melting point or decomposition point of the resin constituting the first inner cylindrical body (11).