A heat exchange module having a heat transfer fluid channel and a heat transfer plate in heat transfer relation with fluid in the channel. The reference side of a thermoelectric cooler (TEC) is in thermal contact with the plate. A heat transfer tile is in thermal contact with a user side of the TEC. The module is configured to be operatively positionable with the tile in heat transfer relation with skin of a patient.

A system includes a treatment cap assembly and a cooling and compression unit coupled to the treatment cap assembly. The treatment cap assembly comprises a fluid circulating pad configured to circulate a cooling fluid; and a compression hood configured to administer compression to a scalp of an individual wearing the treatment cap assembly. The cooling and compression unit is configured to provide the cooling fluid to the fluid circulating pad and to periodically provide compressed gas to the compression hood. The system can be used in a method that includes administering to an individual a dosage of a chemotherapeutic agent; cooling a scalp of the individual to a temperature of less than about 65? F.; and periodically administering compression to the scalp of the individual during the step of administering the dosage of the chemotherapeutic agent.

A composition for use in cooling therapy and treatment of chemically induced alopecia (CIA), said composition containing a reactive oxygen species (ROS) inhibitor.

A thermal pack comprises a first and second plastic sheets that form a sack. The sack contains a flowable thermal material and further includes a plurality of joint lines within the sack that are in contact with the thermal material.

Hypothermic therapy headgear for patients includes a headpiece for engaging the head of the patient and a cooling member engaged to the headpiece for contacting at least one surface portion of the patient. The cooling member includes at least one cooling surface for contacting the surface portion of the patient, and at least two endothermic reaction components. The endothermic reaction components have an initial state where the endothermic reaction components are separated from contact with each other, and a treatment state in which the endothermic reaction components are placed into contact, wherein an endothermic reaction takes place and cools the cooling surface and the corresponding portion of the patient. An activation device selectively places the endothermic reaction components into the treatment state when a patient is in need of hypothermic therapy. A thermal therapy device and a method for administering thermal therapy are also disclosed.

A cooling pack is provided that can both maintain the human body at a suitable, low temperature and ensure a sufficient usage time. The present invention, in one aspect thereof, is directed to a cooling pack that cools a human body. The cold storage layer includes: a freezing medium having a phase transition temperature specified in a range of temperature suitable to maintain the human body at low temperature; and a cold-storage-layer-packaging member containing the freezing medium therein. The buffer layer includes: an antifreeze medium flexible at the phase transition temperature of the freezing medium; and a buffer-layer-packaging member made of a flexible material and containing the antifreeze medium therein. The buffer layer has a prescribed thermal conductivity, thermal diffusivity, thermal effusivity, and heat transmission coefficient. The buffer layer is brought into contact with human skin to transfer heat between the human body and the cold storage layer.

Disclosed is an article consisting of at least two sheets stacked and welded to define a paving including at least three tiles, each having at least three sides and vertices, arranged to define a plane, the tiles being adjacent and connected to each other by at least one of the sides, the tiles including at least one compartment including at least a material absorbent to an aqueous medium or a filler material, the tiles being closed and connected to each other by at least one weld. The weld includes a frangible line with a series of weakening welds and junction points or a pre-cut bordered to either side with a mix weld, the mix weld being broadened close to the vertex of each tile so the corner of the tiles is reinforced by an enlarged weld surface area. Also disclosed are a production method and a device.

Disclosed is a system for regulating body temperature of a subject. The system includes: one or more sensors for monitoring environmental and/or physiological parameters; a multi-layered garment having a plurality of thermoelectric elements distributed throughout the multi-layered garment; a controller for receiving input from the one or more sensors and connected to the plurality of thermoelectric elements to systemically control the thermoelectric elements based on the environmental and/physiological parameters; and a battery for providing power to the one or more sensors, the thermoelectric elements, the controller or a combination of any of these. The system can improve worker safety and comfort in an energy efficient manner.

A heat exchange module alone or part of a system including a control console. The module includes a channel assembly and a heat exchange stack attached thereto, and can be used to directly cool and/or heat tissue or skin. The channel assembly includes a liquid channel. The stack can include a pair of spaced plates with thermoelectric coolers exchangers, heat reflective layers, and a core composite layer which keeps the plates spaced. To provide flexibility of the module to better fit on round body parts the stack can include a thermally-conductive plate construction between the plates which has rotational flexibility axes in the X and/or Y directions between plate portions. Optionally the channel can include windows to which the plate portions are sealed. The heat exchange stack separately or together with the channel assembly can be secured in the thickness direction with mechanical securements such as sewing or tacking to also provide for greater flexibility.

The present invention is directed to a thermo-regulation device for treating an area with in need of thermal regulation. The invention includes a device configured to be fitted over an area in need of thermal regulation; wherein a plurality of cells are integral to the covering body, each cell is equipped with at least one of a plurality of reactants. Each cell of the present invention is in one configuration joined to a neighboring cell by a destructible barrier. The reactants are configured to produce a thermal event when combined with at least one other reactant.